ID   G2P1W5_STRV4            Unreviewed;       486 AA.
AC   G2P1W5;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   24-JAN-2024, entry version 50.
DE   SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:AEM81278.1};
GN   ORFNames=Strvi_1538 {ECO:0000313|EMBL:AEM81278.1};
OS   Streptomyces violaceusniger (strain Tu 4113).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
OX   NCBI_TaxID=653045 {ECO:0000313|EMBL:AEM81278.1, ECO:0000313|Proteomes:UP000008703};
RN   [1] {ECO:0000313|EMBL:AEM81278.1, ECO:0000313|Proteomes:UP000008703}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tu 4133 {ECO:0000313|Proteomes:UP000008703};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ivanova N., Daligault H., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hagen A., Katz L.,
RA   Fiedler H.-P., Keasling J., Fortman J., Woyke T.;
RT   "Complete sequence of chromosome of Streptomyces violaceusniger Tu 4113.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002994; AEM81278.1; -; Genomic_DNA.
DR   RefSeq; WP_014054789.1; NC_015957.1.
DR   AlphaFoldDB; G2P1W5; -.
DR   KEGG; svl:Strvi_1538; -.
DR   eggNOG; COG2206; Bacteria.
DR   HOGENOM; CLU_000445_92_14_11; -.
DR   Proteomes; UP000008703; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   InterPro; IPR006675; HDIG_dom.
DR   NCBIfam; TIGR00277; HDIG; 1.
DR   PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR   PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AEM81278.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        65..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        106..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        151..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          244..439
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   DOMAIN          266..388
FT                   /note="HD"
FT                   /evidence="ECO:0000259|PROSITE:PS51831"
FT   REGION          438..486
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   486 AA;  50463 MW;  C235809E7AEE67E5 CRC64;
     MRALPHGARA YVLCAVLAGG LCAAPAVRPG AAVPWATAAL LAVVHAVGSR VRARWPEWCS
     PVLLAGAFLL PPAAAALVAV PGALLARVER PPAGTRRAWR AARLSLAVWA ASCAFAALGG
     SRALSALWAL GGGAQDPAAQ LAVAEASGTP GFAYALAAAV AAALVLGLTA TALEGGVLVT
     AERHSPRAAW CGRLPGALAP YLVHGPAGLA MAVLWRSPYG PAAALLVLLP MYVCACGFVL
     YRRESAAHQA TIRALVQAVD IKDRYTRGHS ERVGRASAMI ARELGMSGDR LEVVRIAGIL
     HDVGKLGVPT RLLRKNGPLT PDERRVIELH PEYGDEMVRG IGFLGEARAA ILHHHERLDG
     SGYPYGLAGA QIPEFARVVA VADAFDAMTS TRTYRRARPV DTAVEELKRC AGSQFDPRMV
     RALSTALDRH GWHAAVTADA PEERGNVPPD PLSPPLELPP LVRAAASGSA DGPEPRPGLG
     APGGGP
//