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Protein

Glutamate decarboxylase

Gene

Strvi_8912

Organism
Streptomyces violaceusniger Tu 4113
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciSVIO653045:GHK6-8734-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:Strvi_8912Imported
OrganismiStreptomyces violaceusniger Tu 4113Imported
Taxonomic identifieri653045 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000008703: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

G2P1E8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALHKGTRGR RDREERPEIS INPLYGEANP VSGMTGKPPR RRLPDEPMAA
60 70 80 90 100
TTAYQFVHDE LMLDGNARQN LATFVTTWME PQAGKLMSDC RDKNMIDKDE
110 120 130 140 150
YPRTAELERR CVVMLAHLWH APDPDTVVGC STTGSSEACM LAGMAFKRRW
160 170 180 190 200
AQRNPVSYPA TARPNLIMGT NVQVCWEKFC NFWEVEARQV PMEGNRFHLD
210 220 230 240 250
PQAAAELCDE NTIGVVTILG STFDGSYEPV AEVCRALDDL QERTGLDIPV
260 270 280 290 300
HVDGASGAMI APFLDQDLVW DFQLPRVASI NTSGHKYGLV YPGVGWALWR
310 320 330 340 350
TSDALPEDLV FRVDYLGGDM PTFSLNFSRP GAQVAAQYYT FVRLGREGFR
360 370 380 390 400
AVQQNTRDVA RSLAERIEAF GDFTMLSRGD ELPVFAFTTA EGVGTFDVYD
410 420 430 440 450
VSRRLRERGW LVPAYTFPPN REDLSVLRVV CRNGFSEDLA DLFLNDLESL
460 470
LPELRSQPAP LGKVVKAFHH
Length:470
Mass (Da):52,705
Last modified:November 16, 2011 - v1
Checksum:i33A58D9950D36235
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002994 Genomic DNA. Translation: AEM88213.1.
RefSeqiYP_004818493.1. NC_015957.1.

Genome annotation databases

EnsemblBacteriaiAEM88213; AEM88213; Strvi_8912.
GeneIDi11090931.
KEGGisvl:Strvi_8912.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002994 Genomic DNA. Translation: AEM88213.1.
RefSeqiYP_004818493.1. NC_015957.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEM88213; AEM88213; Strvi_8912.
GeneIDi11090931.
KEGGisvl:Strvi_8912.

Phylogenomic databases

KOiK01580.

Enzyme and pathway databases

BioCyciSVIO653045:GHK6-8734-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Streptomyces violaceusniger Tu 4113."
    US DOE Joint Genome Institute
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Ivanova N., Daligault H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hagen A.
    , Katz L., Fiedler H.-P., Keasling J., Fortman J., Woyke T.
    Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Tu 4113Imported.

Entry informationi

Entry nameiG2P1E8_STRVO
AccessioniPrimary (citable) accession number: G2P1E8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: February 4, 2015
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.