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Protein

Xylose isomerase

Gene

xylA

Organism
Streptomyces sp. (strain SirexAA-E / ActE)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei56UniRule annotation1
Active sitei59UniRule annotation1
Metal bindingi183Magnesium 1UniRule annotation1
Metal bindingi219Magnesium 1UniRule annotation1
Metal bindingi219Magnesium 2UniRule annotation1
Metal bindingi222Magnesium 2UniRule annotation1
Metal bindingi247Magnesium 1UniRule annotation1
Metal bindingi289Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSSP862751:G1GPM-5304-MONOMER
SSP862751:G1GPM-5897-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:SACTE_5230Imported, SACTE_5828Imported
OrganismiStreptomyces sp. (strain SirexAA-E / ActE)Imported
Taxonomic identifieri862751 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000001397 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi862751.SACTE_5828

Structurei

3D structure databases

ProteinModelPortaliG2NRI0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 266AP_endonuc_2InterPro annotationAdd BLAST224

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
KOiK01805
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013453 XylA_actinobac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02631 xylA_Arthro, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

G2NRI0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPERFTPTPE DKFTFGLWTV GWRGNDPFGE PTRPVLDPVE SVERLAELGA
60 70 80 90 100
HGVTFHDDDL IPFGSDDRER ARLVGRFREA LERTGLKVPM ATTNLFTHPV
110 120 130 140 150
FKDGGFTSND RDVRRFALRK VIRNIDLAVE LGAQTYVAWG GREGAESGAA
160 170 180 190 200
KDVRSALDRM KEAFDLLGDY VTEQGYDLRF AIEPKPNEPR GDILLPTIGH
210 220 230 240 250
ALAFIERLER PELVGVNPET GHEQMAGLNF PHGIAQALWA GKLFHIDLNG
260 270 280 290 300
QSGIKYDQDF RFGAGDLRQA FWLVDLLETA GWDGSRHFDF KPVRTDGIDG
310 320 330 340 350
VWESAKNCMR NYLILKERAA AFRADPAVQE ALTASRLDEL ARPTADDGLK
360 370 380
ALLADRTAYE DFDATAAAER SMAFEALDQL AMDHLLNVR
Length:389
Mass (Da):43,444
Last modified:November 16, 2011 - v1
Checksum:i4AD0522DB812E433
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002993 Genomic DNA Translation: AEN13046.1
CP002993 Genomic DNA Translation: AEN13613.1
RefSeqiWP_014048996.1, NC_015953.1

Genome annotation databases

EnsemblBacteriaiAEN13046; AEN13046; SACTE_5230
AEN13613; AEN13613; SACTE_5828
KEGGissx:SACTE_5230
ssx:SACTE_5828
PATRICifig|862751.12.peg.5432

Similar proteinsi

Entry informationi

Entry nameiG2NRI0_STREK
AccessioniPrimary (citable) accession number: G2NRI0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: May 23, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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