SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

G2NNB6

- G2NNB6_9ACTO

UniProt

G2NNB6 - G2NNB6_9ACTO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable DNA ligase

Gene
lig, SACTE_0610
Organism
Streptomyces sp. SirexAA-E
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity.UniRule annotation

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

Cofactori

Divalent metal cations By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei208 – 2081ATP By similarityUniRule annotation
Active sitei210 – 2101N6-AMP-lysine intermediate By similarityUniRule annotation
Binding sitei215 – 2151ATP By similarityUniRule annotation
Binding sitei230 – 2301ATP By similarityUniRule annotation
Binding sitei259 – 2591ATP By similarityUniRule annotation
Binding sitei299 – 2991ATP By similarityUniRule annotation
Binding sitei377 – 3771ATP By similarityUniRule annotation
Binding sitei383 – 3831ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
  4. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. DNA ligation involved in DNA repair Source: InterPro
  4. DNA recombination Source: UniProtKB-HAMAP
  5. DNA replication Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

Cell cycle, Cell divisionUniRule annotation, DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSSP862751:GHMW-611-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]
Gene namesi
Name:ligUniRule annotation
ORF Names:SACTE_0610Imported
OrganismiStreptomyces sp. SirexAA-EImported
Taxonomic identifieri862751 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000001397: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK01971.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPiMF_00407. DNA_ligase.
InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2NNB6-1 [UniParc]FASTAAdd to Basket

« Hide

MLLARLAHVS LEVAATSARN RKVALLAGLF RETGPDDVPT VIPYLAGRLP    50
QGRLGIGWSA LSDPPRPADT PVLTVAEAHA ELTAVGALSG PGSQAARKER 100
LRRLFAAATA DEQHFLRGLL TGELRQGALE ALAADALAAA TGAPPADVRR 150
AVMLAGSLQS VARALLADGP EALAAFRLTV GRPVLPMLAH TAGSVTEAVD 200
KLGPCAVEEK LDGIRVQVHR DGAGVRIYTR TLDDITDRLP EPATAVARFP 250
GERFVLDGEV IALGPDGRPR PFQETAARVG SRRDVATAAA AVPVVAVFFD 300
VLALDGRELI DLPFTERHTA LDTLVPEPMR VRRVTVTDPR DPAARRAAEE 350
FFEAALGRGH EGVVAKGASA PYSAGRRGAS WLKVKPVHTL DLVVLAAEWG 400
HGRRTGKLSN LHLGARRPDG TFAMLGKTFK GLTDTMLAWQ TERLLELSTG 450
DDGHVVTVRP ELVVEIAYDG LQDSTRYPAG VTLRFARVLG YREDKPPEEA 500
DTVDTVLSRR A 511
Length:511
Mass (Da):54,502
Last modified:November 16, 2011 - v1
Checksum:i4362F0B5505FDDB3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002993 Genomic DNA. Translation: AEN08547.1.
RefSeqiYP_004801087.1. NC_015953.1.

Genome annotation databases

EnsemblBacteriaiAEN08547; AEN08547; SACTE_0610.
GeneIDi11102866.
KEGGissx:SACTE_0610.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002993 Genomic DNA. Translation: AEN08547.1 .
RefSeqi YP_004801087.1. NC_015953.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEN08547 ; AEN08547 ; SACTE_0610 .
GeneIDi 11102866.
KEGGi ssx:SACTE_0610.

Phylogenomic databases

KOi K01971.

Enzyme and pathway databases

BioCyci SSP862751:GHMW-611-MONOMER.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPi MF_00407. DNA_ligase.
InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Biochemical Properties and Atomic Resolution Structure of a Proteolytically Processed beta-Mannanase from Cellulolytic Streptomyces sp. SirexAA-E."
    Takasuka T.E., Acheson J.F., Bianchetti C.M., Prom B.M., Bergeman L.F., Book A.J., Currie C.R., Fox B.G.
    PLoS ONE 9:E94166-E94166(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SirexAA-EImported.

Entry informationi

Entry nameiG2NNB6_9ACTO
AccessioniPrimary (citable) accession number: G2NNB6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 3, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi