Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

G2N8X6

- G2N8X6_MYCTX

UniProt

G2N8X6 - G2N8X6_MYCTX

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamate decarboxylase

Gene

gadB

Organism
Mycobacterium tuberculosis CTRI-2
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciMTUB707235:GLGU-3499-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadBImported
ORF Names:MTCTRI2_3500Imported
OrganismiMycobacterium tuberculosis CTRI-2Imported
Taxonomic identifieri707235 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000008531: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiG2N8X6.

Structurei

3D structure databases

ProteinModelPortaliG2N8X6.
SMRiG2N8X6. Positions 12-447.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.
OMAiPTFQINF.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

G2N8X6 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRSHPSVPA HSIAPAYTGR MFTAPVPALR MPDESMDPEA AYRFIHDELM
60 70 80 90 100
LDGSSRLNLA TFVTTWMDPE AEKLMAETFD KNMIDKDEYP ATAAIEARCV
110 120 130 140 150
SMVADLFHAE GLRDHDPTSA TGVSTIGSSE AVMLGGLALK WRWRQRVGSW
160 170 180 190 200
KGRMPNLVMG SNVQVVWEKF CRYFDVEPRY LPMERGRYVI TPEQVLAAVD
210 220 230 240 250
ENTIGVVAIL GTTYTGELEP IAEICAALDK LAAGGGVDVP VHVDAASGGF
260 270 280 290 300
VVPFLHPDLV WDFRLPRVVS INVSGHKYGL TYPGVGFVVW RGPEHLPEDL
310 320 330 340 350
VFRVNYLGGD MPTFTLNFSR PGNQVVGQYY NFLRLGRDGY TKVMQALSHT
360 370 380 390 400
ARWLGDQLRE VDHCEVISDG SAIPVVSFRL AGDRGYTEFD VSHELRTFGW
410 420 430 440 450
QVPAYTMPDN ATDVAVLRIV VREGLSADLA RALHDDAVTA LAALDKVKPG
460
GHFDAQHFAH
Length:460
Mass (Da):50,780
Last modified:November 16, 2011 - v1
Checksum:iB5DA3156D4C7CB4F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002992 Genomic DNA. Translation: AEN01899.1.
RefSeqiYP_005918520.1. NC_017524.1.

Genome annotation databases

EnsemblBacteriaiAEN01899; AEN01899; MTCTRI2_3500.
GeneIDi12508670.
KEGGimto:MTCTRI2_3500.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002992 Genomic DNA. Translation: AEN01899.1 .
RefSeqi YP_005918520.1. NC_017524.1.

3D structure databases

ProteinModelPortali G2N8X6.
SMRi G2N8X6. Positions 12-447.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi G2N8X6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEN01899 ; AEN01899 ; MTCTRI2_3500 .
GeneIDi 12508670.
KEGGi mto:MTCTRI2_3500.

Phylogenomic databases

KOi K01580.
OMAi PTFQINF.

Enzyme and pathway databases

BioCyci MTUB707235:GLGU-3499-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CTRI-2Imported.

Entry informationi

Entry nameiG2N8X6_MYCTX
AccessioniPrimary (citable) accession number: G2N8X6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 29, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3