ID   G2MUR7_9THEO            Unreviewed;       325 AA.
AC   G2MUR7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=ATP-grasp domain-containing protein {ECO:0000259|PROSITE:PS50975};
GN   ORFNames=Thewi_0080 {ECO:0000313|EMBL:AEM77590.1};
OS   Thermoanaerobacter wiegelii Rt8.B1.
OC   Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Thermoanaerobacter.
OX   NCBI_TaxID=697303 {ECO:0000313|EMBL:AEM77590.1, ECO:0000313|Proteomes:UP000008276};
RN   [1] {ECO:0000313|EMBL:AEM77590.1, ECO:0000313|Proteomes:UP000008276}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rt8.B1 {ECO:0000313|EMBL:AEM77590.1,
RC   ECO:0000313|Proteomes:UP000008276};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Zeytun A., Daligault H., Detter J.C., Han C.,
RA   Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hemme C.,
RA   Woyke T.;
RT   "Complete sequence of Thermoanaerobacter wiegelii Rt8.B1.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the D-alanine--D-alanine ligase family.
CC       {ECO:0000256|ARBA:ARBA00010871}.
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DR   EMBL; CP002991; AEM77590.1; -; Genomic_DNA.
DR   AlphaFoldDB; G2MUR7; -.
DR   STRING; 697303.Thewi_0080; -.
DR   KEGG; twi:Thewi_0080; -.
DR   eggNOG; COG1181; Bacteria.
DR   HOGENOM; CLU_2866383_0_0_9; -.
DR   Proteomes; UP000008276; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR011095; Dala_Dala_lig_C.
DR   PANTHER; PTHR23132; D-ALANINE--D-ALANINE LIGASE; 1.
DR   PANTHER; PTHR23132:SF0; D-ALANINE-D-ALANINE LIGASE FAMILY; 1.
DR   Pfam; PF07478; Dala_Dala_lig_C; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409}.
FT   DOMAIN          105..316
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
SQ   SEQUENCE   325 AA;  37119 MW;  0C626B1A8D4F7597 CRC64;
     MKIGVLWRKF RNVEFQRKLT PDKVYDDAYD EAYHHYMAIK EAGFDSVLIE WKEDPLETYE
     TIKKEKVDLI FNASSMKEVA FLEVFNIPYV GSGLDVVATD KRMRKDIVAS HGLPTPKYVI
     AQNPQEIPSV DHLKFPLFAK PISGRGSAGI DEENIIYDKD KLPQVVSKIT DKIGQAALIE
     EFIEGKEVTV GIIGYKHPQV LPLLEVGYNN VKTNTYEHKM FDNEIIKCPM EVSKEVEEKI
     KETALNIYKV LNAKDFARID MILSKDNVPY FLELNTFAGL TMSSSKGEKH VHHGYMGYMA
     KAAGLTRGEF IRKIIESAIE RYKLK
//