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G2MRX8

- G2MRX8_9THEO

UniProt

G2MRX8 - G2MRX8_9THEO

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Protein
Xylose isomerase
Gene
xylA, Thewi_0220
Organism
Thermoanaerobacter wiegelii Rt8.B1
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei100 – 1001 By similarityUniRule annotation
Active sitei103 – 1031 By similarityUniRule annotation
Metal bindingi231 – 2311Magnesium 1 By similarityUniRule annotation
Metal bindingi267 – 2671Magnesium 1 By similarityUniRule annotation
Metal bindingi267 – 2671Magnesium 2 By similarityUniRule annotation
Metal bindingi270 – 2701Magnesium 2 By similarityUniRule annotation
Metal bindingi295 – 2951Magnesium 1 By similarityUniRule annotation
Metal bindingi306 – 3061Magnesium 2 By similarityUniRule annotation
Metal bindingi308 – 3081Magnesium 2 By similarityUniRule annotation
Metal bindingi338 – 3381Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciTWIE697303:GH3A-234-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:Thewi_0220Imported
OrganismiThermoanaerobacter wiegelii Rt8.B1Imported
Taxonomic identifieri697303 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeThermoanaerobacter
ProteomesiUP000008276: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliG2MRX8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2MRX8-1 [UniParc]FASTAAdd to Basket

« Hide

MEYFKNVPQI KYEGPKSNNP YAFKFYNPDE IIDGKPLKEH LRFSVAYWHT    50
FTWSGTDPFG APTMQRPWDH LSDPMDIAKA RVEAAFELFE KLDVPFFCFH 100
DRDIAPEGET LRETNKNLDT IVVMIKDYLK TSKTKVLWGT ANLFSNPRFV 150
HGAATSCNAD VFAYAAAQVK KALEITKELG GQNYVFWGGR EGYETLLNTD 200
MELEFDNLAR FLHMAVEYAQ EIGFEGQFLI EPKPKEPTKH QYDFDAASVH 250
AFLKKYDLDK YFKLNIEANH ATLAGHDFQH ELRYARINNM LGSIDANMGD 300
MLLGWDTDQY PTDIRMTTLA MYEVIKMGGF NKGGLNFDAK VRRASFEPED 350
LFLGHIAGMD AFAKGFKVAY KIVKDGVFDR FIEERYKSYR EGIGAEIVNG 400
KANFKTLEEY ALNNPKIENK SGKQELLESI LNQYLFSE 438
Length:438
Mass (Da):50,287
Last modified:November 16, 2011 - v1
Checksum:i4AEC61D56B32C645
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002991 Genomic DNA. Translation: AEM77724.1.
RefSeqiYP_004819008.1. NC_015958.1.

Genome annotation databases

EnsemblBacteriaiAEM77724; AEM77724; Thewi_0220.
GeneIDi11082441.
KEGGitwi:Thewi_0220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002991 Genomic DNA. Translation: AEM77724.1 .
RefSeqi YP_004819008.1. NC_015958.1.

3D structure databases

ProteinModelPortali G2MRX8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEM77724 ; AEM77724 ; Thewi_0220 .
GeneIDi 11082441.
KEGGi twi:Thewi_0220.

Phylogenomic databases

KOi K01805.

Enzyme and pathway databases

BioCyci TWIE697303:GH3A-234-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Thermoanaerobacter wiegelii Rt8.B1."
    US DOE Joint Genome Institute
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Zeytun A., Daligault H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hemme C., Woyke T.
    Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Rt8.B1Imported.

Entry informationi

Entry nameiG2MRX8_9THEO
AccessioniPrimary (citable) accession number: G2MRX8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: June 11, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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