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G2MME4

- G2MME4_9ARCH

UniProt

G2MME4 - G2MME4_9ARCH

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Protein

Lysine--tRNA ligase

Gene
lysS, Halar_2699
Organism
halophilic archaeon DL31
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. lysine-tRNA ligase activity Source: UniProtKB-HAMAP
  3. tRNA binding Source: InterPro

GO - Biological processi

  1. lysyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotationImported, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHARC756883:GJDQ-2011-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Lysine--tRNA ligaseUniRule annotation (EC:6.1.1.6UniRule annotation)
Alternative name(s):
Lysyl-tRNA synthetase
Gene namesi
Name:lysSUniRule annotation
ORF Names:Halar_2699Imported
Organismihalophilic archaeon DL31Imported
Taxonomic identifieri756883 [NCBI]
Taxonomic lineageiArchaea
ProteomesiUP000010096: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi41 – 499"HIGH" region By similarityUniRule annotation
Motifi307 – 3115"KMSKS" region By similarityUniRule annotation

Sequence similaritiesi

Phylogenomic databases

KOiK04566.

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00177. Lys_tRNA_synth_class1.
InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR002904. Lys-tRNA-ligase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF01921. tRNA-synt_1f. 1 hit.
[Graphical view]
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00467. lysS_arch. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2MME4-1 [UniParc]FASTAAdd to Basket

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MSSDDRHGDR SFHAFWADTV ADEIEASEPE EPIVIKGGVS PSGIPHLGHF    50
NEILRGHFVA EVLRERGHEV RQVFMSDDRD PLRKLPRRLA DADWNVVELG 100
DVDAGALGKN LGKPYTDIPD PFGECHDSYG EHFADLLSQA ADMVDVPVEV 150
LSNTEMYESG EFEPQIRTIL ENVETAREVL AGYQNSVDES YSPFRVVCQE 200
CGIVTTDVTV TDLGEGIVSY ACTGMTAGGR DIEGCGHEGE ATLRDGKLSW 250
RFEWPAQWSL LGVDFEPFGK DHAEGSWPSG EEIMREVLGE EPPVPMTYEW 300
FTLNGEPLSS SEGNVVTVPE VLELLEPEVL RYFFALDPNK ARDFDVSRLD 350
QLVDDFDRFE RAHFGDVDDE ELTRVAERAY PFVVDEVRAD RVRLPYTFAA 400
VLGMVDDRHL RLQMAQNEGH IPEDAPEWVV DDALARVEKA RAWAERCDNA 450
YNYRLQPDLP DAAFDDAVAA ALDELAAFVE AGNDGEAIQG EIYETAKRHD 500
IEVGDLFAAG YRLFFDQTQG PRLGEFMGEL DREFVVQRLR RDG 543
Length:543
Mass (Da):60,899
Last modified:November 16, 2011 - v1
Checksum:i020D9BB14C6A1BDB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002988 Genomic DNA. Translation: AEN06343.1.
RefSeqiWP_014052114.1. NC_015954.1.
YP_004808716.1. NC_015954.1.

Genome annotation databases

EnsemblBacteriaiAEN06343; AEN06343; Halar_2699.
GeneIDi11096068.
KEGGihah:Halar_2699.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002988 Genomic DNA. Translation: AEN06343.1 .
RefSeqi WP_014052114.1. NC_015954.1.
YP_004808716.1. NC_015954.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEN06343 ; AEN06343 ; Halar_2699 .
GeneIDi 11096068.
KEGGi hah:Halar_2699.

Phylogenomic databases

KOi K04566.

Enzyme and pathway databases

BioCyci HARC756883:GJDQ-2011-MONOMER.

Family and domain databases

Gene3Di 1.10.10.350. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00177. Lys_tRNA_synth_class1.
InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR002904. Lys-tRNA-ligase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF01921. tRNA-synt_1f. 1 hit.
[Graphical view ]
SUPFAMi SSF48163. SSF48163. 1 hit.
TIGRFAMsi TIGR00467. lysS_arch. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of halophilic archaeon DL31."
    US DOE Joint Genome Institute
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Dyall-Smith M., Cavicchioli R., Woyke T.
    Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DL31Imported.

Entry informationi

Entry nameiG2MME4_9ARCH
AccessioniPrimary (citable) accession number: G2MME4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 3, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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