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G2MME4 (G2MME4_9ARCH) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Lysine--tRNA ligase HAMAP-Rule MF_00177

EC=6.1.1.6 HAMAP-Rule MF_00177
Alternative name(s):
Lysyl-tRNA synthetase HAMAP-Rule MF_00177
Gene names
Name:lysS HAMAP-Rule MF_00177
ORF Names:Halar_2699 EMBL AEN06343.1
Organismhalophilic archaeon DL31 [Complete proteome] EMBL AEN06343.1
Taxonomic identifier756883 [NCBI]
Taxonomic lineageArchaea

Protein attributes

Sequence length543 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP-Rule MF_00177

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00177.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. RuleBase RU003489 HAMAP-Rule MF_00177

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif41 – 499"HIGH" region By similarity HAMAP-Rule MF_00177
Motif307 – 3115"KMSKS" region By similarity HAMAP-Rule MF_00177

Sequences

Sequence LengthMass (Da)Tools
G2MME4 [UniParc].

Last modified November 16, 2011. Version 1.
Checksum: 020D9BB14C6A1BDB

FASTA54360,899
        10         20         30         40         50         60 
MSSDDRHGDR SFHAFWADTV ADEIEASEPE EPIVIKGGVS PSGIPHLGHF NEILRGHFVA 

        70         80         90        100        110        120 
EVLRERGHEV RQVFMSDDRD PLRKLPRRLA DADWNVVELG DVDAGALGKN LGKPYTDIPD 

       130        140        150        160        170        180 
PFGECHDSYG EHFADLLSQA ADMVDVPVEV LSNTEMYESG EFEPQIRTIL ENVETAREVL 

       190        200        210        220        230        240 
AGYQNSVDES YSPFRVVCQE CGIVTTDVTV TDLGEGIVSY ACTGMTAGGR DIEGCGHEGE 

       250        260        270        280        290        300 
ATLRDGKLSW RFEWPAQWSL LGVDFEPFGK DHAEGSWPSG EEIMREVLGE EPPVPMTYEW 

       310        320        330        340        350        360 
FTLNGEPLSS SEGNVVTVPE VLELLEPEVL RYFFALDPNK ARDFDVSRLD QLVDDFDRFE 

       370        380        390        400        410        420 
RAHFGDVDDE ELTRVAERAY PFVVDEVRAD RVRLPYTFAA VLGMVDDRHL RLQMAQNEGH 

       430        440        450        460        470        480 
IPEDAPEWVV DDALARVEKA RAWAERCDNA YNYRLQPDLP DAAFDDAVAA ALDELAAFVE 

       490        500        510        520        530        540 
AGNDGEAIQG EIYETAKRHD IEVGDLFAAG YRLFFDQTQG PRLGEFMGEL DREFVVQRLR 


RDG 

« Hide

References

[1]"Complete sequence of chromosome of halophilic archaeon DL31."
US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Dyall-Smith M., Cavicchioli R., Woyke T.
Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DL31 EMBL AEN06343.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002988 Genomic DNA. Translation: AEN06343.1.
RefSeqYP_004808716.1. NC_015954.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEN06343; AEN06343; Halar_2699.
GeneID11096068.
KEGGhah:Halar_2699.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK04566.

Enzyme and pathway databases

BioCycHARC756883:GJDQ-2011-MONOMER.

Family and domain databases

Gene3D1.10.10.350. 1 hit.
3.40.50.620. 2 hits.
HAMAPMF_00177. Lys_tRNA_synth_class1.
InterProIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR002904. Lys-tRNA-ligase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01921. tRNA-synt_1f. 1 hit.
[Graphical view]
SUPFAMSSF48163. SSF48163. 1 hit.
TIGRFAMsTIGR00467. lysS_arch. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG2MME4_9ARCH
AccessionPrimary (citable) accession number: G2MME4
Entry history
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: June 11, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)