Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Lysine--tRNA ligase

Gene

lysS

Organism
halophilic archaeon DL31
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHARC756883:G1GZU-1922-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Lysine--tRNA ligaseUniRule annotation (EC:6.1.1.6UniRule annotation)
Alternative name(s):
Lysyl-tRNA synthetaseUniRule annotation
Short name:
LysRSUniRule annotation
Gene namesi
Name:lysSUniRule annotation
ORF Names:Halar_2699Imported
Organismihalophilic archaeon DL31Imported
Taxonomic identifieri756883 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHaloferacales
Proteomesi
  • UP000010096 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi756883.Halar_2699

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi41 – 49"HIGH" regionUniRule annotation9
Motifi307 – 311"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00485 Archaea
COG1384 LUCA
KOiK04566
OrthoDBiPOG093Z01CB

Family and domain databases

Gene3Di1.10.10.350, 1 hit
2.30.30.300, 1 hit
3.40.50.620, 2 hits
HAMAPiMF_00177 Lys_tRNA_synth_class1, 1 hit
InterProiView protein in InterPro
IPR008925 aa-tRNA-synth_I_codon-bd
IPR020751 aa-tRNA-synth_I_codon-bd_sub2
IPR001412 aa-tRNA-synth_I_CS
IPR002904 Lys-tRNA-ligase
IPR023386 Lys-tRNA-ligase_insertion_sf
IPR014729 Rossmann-like_a/b/a_fold
PANTHERiPTHR37940 PTHR37940, 1 hit
SUPFAMiSSF48163 SSF48163, 1 hit
TIGRFAMsiTIGR00467 lysS_arch, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

G2MME4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDDRHGDR SFHAFWADTV ADEIEASEPE EPIVIKGGVS PSGIPHLGHF
60 70 80 90 100
NEILRGHFVA EVLRERGHEV RQVFMSDDRD PLRKLPRRLA DADWNVVELG
110 120 130 140 150
DVDAGALGKN LGKPYTDIPD PFGECHDSYG EHFADLLSQA ADMVDVPVEV
160 170 180 190 200
LSNTEMYESG EFEPQIRTIL ENVETAREVL AGYQNSVDES YSPFRVVCQE
210 220 230 240 250
CGIVTTDVTV TDLGEGIVSY ACTGMTAGGR DIEGCGHEGE ATLRDGKLSW
260 270 280 290 300
RFEWPAQWSL LGVDFEPFGK DHAEGSWPSG EEIMREVLGE EPPVPMTYEW
310 320 330 340 350
FTLNGEPLSS SEGNVVTVPE VLELLEPEVL RYFFALDPNK ARDFDVSRLD
360 370 380 390 400
QLVDDFDRFE RAHFGDVDDE ELTRVAERAY PFVVDEVRAD RVRLPYTFAA
410 420 430 440 450
VLGMVDDRHL RLQMAQNEGH IPEDAPEWVV DDALARVEKA RAWAERCDNA
460 470 480 490 500
YNYRLQPDLP DAAFDDAVAA ALDELAAFVE AGNDGEAIQG EIYETAKRHD
510 520 530 540
IEVGDLFAAG YRLFFDQTQG PRLGEFMGEL DREFVVQRLR RDG
Length:543
Mass (Da):60,899
Last modified:November 16, 2011 - v1
Checksum:i020D9BB14C6A1BDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002988 Genomic DNA Translation: AEN06343.1
RefSeqiWP_014052114.1, NC_015954.1

Genome annotation databases

EnsemblBacteriaiAEN06343; AEN06343; Halar_2699
GeneIDi11096068
KEGGihah:Halar_2699

Similar proteinsi

Entry informationi

Entry nameiG2MME4_9EURY
AccessioniPrimary (citable) accession number: G2MME4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 25, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health