Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

G2MME4

- G2MME4_9ARCH

UniProt

G2MME4 - G2MME4_9ARCH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Lysine--tRNA ligase

Gene

lysS

Organism
halophilic archaeon DL31
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. lysine-tRNA ligase activity Source: UniProtKB-HAMAP
  3. tRNA binding Source: InterPro

GO - Biological processi

  1. lysyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotation, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHARC756883:GJDQ-2011-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Lysine--tRNA ligaseUniRule annotation (EC:6.1.1.6UniRule annotation)
Alternative name(s):
Lysyl-tRNA synthetaseUniRule annotation
Gene namesi
Name:lysSUniRule annotation
ORF Names:Halar_2699Imported
Organismihalophilic archaeon DL31Imported
Taxonomic identifieri756883 [NCBI]
Taxonomic lineageiArchaea
ProteomesiUP000010096: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi41 – 499"HIGH" regionUniRule annotation
Motifi307 – 3115"KMSKS" regionUniRule annotation

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

KOiK04566.

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00177. Lys_tRNA_synth_class1.
InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR002904. Lys-tRNA-ligase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF01921. tRNA-synt_1f. 1 hit.
[Graphical view]
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00467. lysS_arch. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2MME4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSDDRHGDR SFHAFWADTV ADEIEASEPE EPIVIKGGVS PSGIPHLGHF
60 70 80 90 100
NEILRGHFVA EVLRERGHEV RQVFMSDDRD PLRKLPRRLA DADWNVVELG
110 120 130 140 150
DVDAGALGKN LGKPYTDIPD PFGECHDSYG EHFADLLSQA ADMVDVPVEV
160 170 180 190 200
LSNTEMYESG EFEPQIRTIL ENVETAREVL AGYQNSVDES YSPFRVVCQE
210 220 230 240 250
CGIVTTDVTV TDLGEGIVSY ACTGMTAGGR DIEGCGHEGE ATLRDGKLSW
260 270 280 290 300
RFEWPAQWSL LGVDFEPFGK DHAEGSWPSG EEIMREVLGE EPPVPMTYEW
310 320 330 340 350
FTLNGEPLSS SEGNVVTVPE VLELLEPEVL RYFFALDPNK ARDFDVSRLD
360 370 380 390 400
QLVDDFDRFE RAHFGDVDDE ELTRVAERAY PFVVDEVRAD RVRLPYTFAA
410 420 430 440 450
VLGMVDDRHL RLQMAQNEGH IPEDAPEWVV DDALARVEKA RAWAERCDNA
460 470 480 490 500
YNYRLQPDLP DAAFDDAVAA ALDELAAFVE AGNDGEAIQG EIYETAKRHD
510 520 530 540
IEVGDLFAAG YRLFFDQTQG PRLGEFMGEL DREFVVQRLR RDG
Length:543
Mass (Da):60,899
Last modified:November 16, 2011 - v1
Checksum:i020D9BB14C6A1BDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002988 Genomic DNA. Translation: AEN06343.1.
RefSeqiWP_014052114.1. NC_015954.1.
YP_004808716.1. NC_015954.1.

Genome annotation databases

EnsemblBacteriaiAEN06343; AEN06343; Halar_2699.
GeneIDi11096068.
KEGGihah:Halar_2699.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002988 Genomic DNA. Translation: AEN06343.1 .
RefSeqi WP_014052114.1. NC_015954.1.
YP_004808716.1. NC_015954.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEN06343 ; AEN06343 ; Halar_2699 .
GeneIDi 11096068.
KEGGi hah:Halar_2699.

Phylogenomic databases

KOi K04566.

Enzyme and pathway databases

BioCyci HARC756883:GJDQ-2011-MONOMER.

Family and domain databases

Gene3Di 1.10.10.350. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00177. Lys_tRNA_synth_class1.
InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR002904. Lys-tRNA-ligase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF01921. tRNA-synt_1f. 1 hit.
[Graphical view ]
SUPFAMi SSF48163. SSF48163. 1 hit.
TIGRFAMsi TIGR00467. lysS_arch. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of halophilic archaeon DL31."
    US DOE Joint Genome Institute
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Dyall-Smith M., Cavicchioli R., Woyke T.
    Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DL31Imported.

Entry informationi

Entry nameiG2MME4_9ARCH
AccessioniPrimary (citable) accession number: G2MME4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: October 29, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3