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G2LRL6 (G2LRL6_9XANT) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE HAMAP-Rule MF_01813

EC=2.1.1.163 HAMAP-Rule MF_01813
EC=2.1.1.201 HAMAP-Rule MF_01813
Alternative name(s):
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase HAMAP-Rule MF_01813
Demethylmenaquinone methyltransferase HAMAP-Rule MF_01813
Gene names
Name:ubiE HAMAP-Rule MF_01813 EMBL AEO40950.1
ORF Names:XACM_0645 EMBL AEO40950.1
OrganismXanthomonas axonopodis pv. citrumelo F1 [Complete proteome] EMBL AEO40950.1
Taxonomic identifier981368 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length253 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) By similarity. HAMAP-Rule MF_01813

Catalytic activity

A demethylmenaquinone + S-adenosyl-L-methionine = a menaquinol + S-adenosyl-L-homocysteine. HAMAP-Rule MF_01813

S-adenosyl-L-methionine + 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol = S-adenosyl-L-homocysteine + 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol. HAMAP-Rule MF_01813

Pathway

Cofactor biosynthesis; menaquinone biosynthesis; menaquinone-2 from chorismate: step 8/8. HAMAP-Rule MF_01813

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP-Rule MF_01813

Sequence similarities

Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiE family. HAMAP-Rule MF_01813

Sequences

Sequence LengthMass (Da)Tools
G2LRL6 [UniParc].

Last modified November 16, 2011. Version 1.
Checksum: B95CAE1C30428CC2

FASTA25327,980
        10         20         30         40         50         60 
MSESPYTSGT THFGFRDVAA KDKQKLVGEV FTSVARNYDL MNDLMSLGVH RAWKRYFVAT 

        70         80         90        100        110        120 
AQVKPGDRVL DLAGGTGDIA VLLKERVGNE GAVVLGDINA GMLSVGRDRL TNRGLVSGFD 

       130        140        150        160        170        180 
YVQCNAEALP FPDQSFDLVT ISFGLRNVTD KDAALREMYR VLKVGGQARV LEFSEVTAEW 

       190        200        210        220        230        240 
FKPIYDFHSF KILPKLGQLF ARDADSYQYL AESIRKHPPQ ESLKGMMGEA GFARCHFKNL 

       250 
TGGIVAIHSG YKI 

« Hide

References

[1]"Comparative Genomic Analysis of Xanthomonas axonopodis pv. citrumelo F1, Which Causes Citrus Bacterial Spot Disease, and Related Strains Provides Insights into Virulence and Host Specificity."
Jalan N., Aritua V., Kumar D., Yu F., Jones J.B., Graham J.H., Setubal J.C., Wang N.
J. Bacteriol. 193:6342-6357(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: F1 EMBL AEO40950.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002914 Genomic DNA. Translation: AEO40950.1.
RefSeqYP_004850248.1. NC_016010.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEO40950; AEO40950; XACM_0645.
GeneID11133135.
KEGGxax:XACM_0645.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK03183.

Enzyme and pathway databases

BioCycXALF981368:GH9H-645-MONOMER.
UniPathwayUPA00079; UER00169.
UPA00232.

Family and domain databases

HAMAPMF_01813. UbiE_methyltran.
InterProIPR004033. UbiE/COQ5_MeTrFase.
IPR023576. UbiE/COQ5_MeTrFase_CS.
[Graphical view]
PfamPF01209. Ubie_methyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01934. MenG_MenH_UbiE. 1 hit.
PROSITEPS51608. SAM_MT_UBIE. 1 hit.
PS01183. UBIE_1. 1 hit.
PS01184. UBIE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG2LRL6_9XANT
AccessionPrimary (citable) accession number: G2LRL6
Entry history
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: March 19, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)