G2LG86 (G2LG86_CHLTF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP-Rule MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP-Rule MF_01401
EC=1.8.4.11 HAMAP-Rule MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP-Rule MF_01401

Gene names

Name:	msrA HAMAP-Rule MF_01401
Ordered Locus Names:	Cabther_A1853 EMBL AEP12599.1

Organism

Chloracidobacterium thermophilum (strain B) [Complete proteome] [HAMAP] EMBL AEP12599.1

Taxonomic identifier

981222 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Fibrobacteres/Acidobacteria group › Acidobacteria › unclassified Acidobacteria › Candidatus Chloracidobacterium › Candidatus Chloracidobacterium thermophilum

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP-Rule MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. SAAS SAAS002569 HAMAP-Rule MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. SAAS SAAS002569 HAMAP-Rule MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP-Rule MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase SAAS SAAS002569 HAMAP-Rule MF_01401 EMBL AEP12599.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cellular protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular_function	peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	14	1	By similarity HAMAP-Rule MF_01401

Sequences

	Sequence		Length	Mass (Da)
	G2LG86 [UniParc]. Last modified November 16, 2011. Version 1. Checksum: A528B3E9A9528266	FASTA	180	20,305
	10 20 30 40 50 60 MTASREVAVL AGGCFWCLEA VYLGMRGVEK VVSGYANGHT PNPTYQQVCS GTTGYAEAVE 70 80 90 100 110 120 ITFDPNEVSY RDLLDVFFVI HDPTTLNRQG ADVGTQYRSG IYYLTPAQHE TARQVVAELT 130 140 150 160 170 180 DKRIFDAPIV TEIEPLRNFY PAEDYHQNYF ARHPYQPYCV AVVAPKVAKF RKHFLEKVKA

References

[1]

"Complete genome of Candidatus Chloracidobacterium thermophilum, a chlorophyll-based photoheterotroph belonging to the phylum Acidobacteria." Garcia Costas A.M., Liu Z., Tomsho L.P., Schuster S.C., Ward D.M., Bryant D.A. Environ. Microbiol. 14:177-190(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: B EMBL AEP12599.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002514 Genomic DNA. Translation: AEP12599.1.
RefSeq	YP_004863115.1. NC_016024.1.
3D structure databases
ProteinModelPortal	G2LG86.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEP12599; AEP12599; Cabther_A1853.
GeneID	11169465.
KEGG	ctm:Cabther_A1853.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K07304.
Enzyme and pathway databases
BioCyc	CTHE981222:GHDQ-2691-MONOMER.
Family and domain databases
Gene3D	3.30.1060.10. 1 hit.
HAMAP	MF_01401. MsrA.
InterPro	IPR002569. Met_Sox_Rdtase_MsrA. [Graphical view]
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. msrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

G2LG86_CHLTF

Accession

Primary (citable) accession number: G2LG86

Entry history

Integrated into UniProtKB/TrEMBL:	November 16, 2011
Last sequence update:	November 16, 2011
Last modified:	April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)