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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Pseudomonas aeruginosa M18
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei140 – 1401UniRule annotation
Active sitei545 – 5451UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciPAER941193:GLIQ-1270-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
ORF Names:PAM18_1259Imported
OrganismiPseudomonas aeruginosa M18Imported
Taxonomic identifieri941193 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000009043: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2KYX0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPEIDARLRE DVHQLGELLG DTIREQYGPR FLDKIELIRK GAKAARRGSA
60 70 80 90 100
EGAQQLTATL DGLEEDELLP VARAFNQFLN LANIAEQYHR IRRRRPNEPE
110 120 130 140 150
PFENLVLEEL LGRLKDAGHA PGQLARQLAG LEIELVLTAH PTEVARRTLI
160 170 180 190 200
QKYDAITAQL AAKDHADLLP EERSRIQQRL QRLVAEAWHT DEIRKVRPTP
210 220 230 240 250
VDEAKWGFAV IEHSLWQALP NVLRHVDEVL LRSTGERLPL TAAPLRFASW
260 270 280 290 300
MGGDRDGNPN VTASVTREVL LLARWMAADL YLRDIDRLAA ELSMQQASPQ
310 320 330 340 350
LLARVGDSAE PYRALLKQLR ERLRVTRNWT HQALAGEVPA AEGVLEHNRD
360 370 380 390 400
LVEPLQLCHE SLHACGMGVI ADGALLDCLR RAATFGLFLV RLDVRQDSAR
410 420 430 440 450
HAAALSEITE YLELGSYDEW DEKTRLEFLL EELNSRRPLL PAHYQPSADT
460 470 480 490 500
AEVLATCRAI AAAPPASLGS YVISMAGQPS DVLAVQLLLK ESGVDWPMRV
510 520 530 540 550
VPLFETLDDL DNAGPCMERL LTLPGYRSRL SGVQEVMIGY SDSAKDAGTL
560 570 580 590 600
TAAWAQYRAQ EKLVEICRQH EVELLLFHGR GGTVGRGGGP AHAAILSQPP
610 620 630 640 650
GSVAGRFRVT EQGEMIRFKF GLPDIAEQNL NLYLAAVLEA TLMPPPAPEP
660 670 680 690 700
AWRAQMDRLA KDALLAYRRV VRDDPQFVEY FRLATPEQEL GRLPLGSRPA
710 720 730 740 750
KRREGGVESL RAIPWIFAWT QTRLMLPAWL GWETALLNAI ERGEGALLGQ
760 770 780 790 800
MRERWPFFTT RIDMLEMVLA KADADIARLY DERLVPLELR PLGRRLRDLL
810 820 830 840 850
SQAVRVVLGL TGQSLLLAHA SETRESISVR NSYLDPLHLL QAELLARSRR
860 870
CRGDACGGLE QALLVTVAGV AAGLRNTG
Length:878
Mass (Da):97,868
Last modified:November 16, 2011 - v1
Checksum:i51D1324A719258DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002496 Genomic DNA. Translation: AEO73746.1.
RefSeqiYP_005973848.1. NC_017548.1.

Genome annotation databases

EnsemblBacteriaiAEO73746; AEO73746; PAM18_1259.
GeneIDi12565288.
KEGGipaf:PAM18_1259.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002496 Genomic DNA. Translation: AEO73746.1.
RefSeqiYP_005973848.1. NC_017548.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEO73746; AEO73746; PAM18_1259.
GeneIDi12565288.
KEGGipaf:PAM18_1259.

Phylogenomic databases

KOiK01595.

Enzyme and pathway databases

BioCyciPAER941193:GLIQ-1270-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genomic analysis and temperature-dependent transcriptome profiles of the rhizosphere originating strain Pseudomonas aeruginosa M18."
    Wu D.Q., Ye J., Ou H.Y., Wei X., Huang X., He Y.W., Xu Y.
    BMC Genomics 12:438-438(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M18Imported.

Entry informationi

Entry nameiG2KYX0_PSEAI
AccessioniPrimary (citable) accession number: G2KYX0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: February 4, 2015
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.