Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase

Gene

gpmA1

Organism
Lactobacillus sanfranciscensis (strain TMW 1.1304)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.UniRule annotation

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei19 – 191Tele-phosphohistidine intermediateUniRule annotation
Binding sitei25 – 2512-phospho-D-glycerateUniRule annotation
Binding sitei70 – 7012-phospho-D-glycerateUniRule annotation
Binding sitei108 – 10812-phospho-D-glycerateUniRule annotation
Active sitei186 – 1861UniRule annotation

GO - Molecular functioni

  1. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciLSAN714313:GIWZ-473-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutaseUniRule annotation (EC:5.4.2.11UniRule annotation)
Short name:
BPG-dependent PGAMUniRule annotation
Short name:
PGAMUniRule annotation
Short name:
PhosphoglyceromutaseUniRule annotation
Short name:
dPGMUniRule annotation
Gene namesi
Name:gpmA1Imported
Synonyms:gpmAUniRule annotation
Ordered Locus Names:LSA_04440Imported
OrganismiLactobacillus sanfranciscensis (strain TMW 1.1304)Imported
Taxonomic identifieri714313 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000001285: Chromosome

Structurei

3D structure databases

ProteinModelPortaliG2KV03.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni31 – 3222-phospho-D-glycerate bindingUniRule annotation
Regioni97 – 10042-phospho-D-glycerate bindingUniRule annotation
Regioni124 – 12522-phospho-D-glycerate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.UniRule annotation

Phylogenomic databases

KOiK01834.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2KV03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKRVSEVDY MSKLVLMRHG ESVANYNHTF TGWSDVSLTD EGRREAHEAG
60 70 80 90 100
RKLNELQIKF DDAHTSYLKR AIISENIVLS EINQLWIPQH KTWRLNERHY
110 120 130 140 150
GALRGQNKQK VRAEVGDEQF MMWRRSFEAV PPRLEVVPDL RRYHDAGIDE
160 170 180 190 200
PRAESLKMAY QRLVPYWIDE IAPRLMNNHN QLVIAHGSSL RALIKYLENI
210 220 230
DDLGIDGVEV GNAEPIIYTL DHDLRILKKE ILN
Length:233
Mass (Da):27,196
Last modified:November 16, 2011 - v1
Checksum:i95CAF36FC1E1B45E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002461 Genomic DNA. Translation: AEN98892.1.
RefSeqiWP_014081750.1. NC_015978.1.
YP_004840824.1. NC_015978.1.

Genome annotation databases

EnsemblBacteriaiAEN98892; AEN98892; LSA_04440.
GeneIDi11149961.
KEGGilsn:LSA_04440.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002461 Genomic DNA. Translation: AEN98892.1.
RefSeqiWP_014081750.1. NC_015978.1.
YP_004840824.1. NC_015978.1.

3D structure databases

ProteinModelPortaliG2KV03.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEN98892; AEN98892; LSA_04440.
GeneIDi11149961.
KEGGilsn:LSA_04440.

Phylogenomic databases

KOiK01834.

Enzyme and pathway databases

BioCyciLSAN714313:GIWZ-473-MONOMER.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genomic analysis reveals Lactobacillus sanfranciscensis as stable element in traditional sourdoughs."
    Vogel R.F., Pavlovic M., Ehrmann M.A., Wiezer A., Liesegang H., Offschanka S., Voget S., Angelov A., Bocker G., Liebl W.
    Microb. Cell Fact. 10:S6-S6(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TMW 1.1304Imported.

Entry informationi

Entry nameiG2KV03_LACSM
AccessioniPrimary (citable) accession number: G2KV03
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: February 4, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.