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G2IV57 (G2IV57_PSEUL) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:NH8B_0174 EMBL BAK75023.1
OrganismPseudogulbenkiania sp. (strain NH8B) [Complete proteome] [HAMAP]
Taxonomic identifier748280 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNeisserialesChromobacteriaceaePseudogulbenkiania

Protein attributes

Sequence length303 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain103 – 298196ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding129 – 18456ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2521Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2651Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2651Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2671Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
G2IV57 [UniParc].

Last modified November 16, 2011. Version 1.
Checksum: FD64ECBFB817C400

FASTA30332,483
        10         20         30         40         50         60 
MKQYGKVAVM MGGTSAEREV SLMSGGGVLK ALQSQGVDAH AFDPAEKPLA ALKDEGFERV 

        70         80         90        100        110        120 
FIALHGPFGE DGTLQGALET MGMPYTGCGV MASAIGMDKW RTKLLWQGAG LPIPAFVLLA 

       130        140        150        160        170        180 
DDSDFAVVEA QLGLPLFVKP ATEGSSIGVT KVKHPGELRA AYEEARRYDK LVIAEAFVGG 

       190        200        210        220        230        240 
GEYTCAIIGD KALPTIKIEP ATEFYDYQAK YFRDDTVYRC PSGLSAEVEQ RARELALTAF 

       250        260        270        280        290        300 
EVLGGRGWGR VDFLMDEAGG IYLLEVNTSP GMTSHSLVPM AARVEGLSYE ELCLAILDMA 


HVG 

« Hide

References

[1]"Complete genome sequence of the denitrifying and N(2)O-reducing bacterium Pseudogulbenkiania sp. strain NH8B."
Ishii S., Tago T., Nishizawa T., Oshima K., Hattori M., Senoo K.
J. Bacteriol. 193:6395-6396(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NH8B.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP012224 Genomic DNA. Translation: BAK75023.1.
RefSeqYP_004845437.1. NC_016002.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAK75023; BAK75023; NH8B_0174.
GeneID11154285.
KEGGpse:NH8B_0174.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycPSP748280:GHJ9-174-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG2IV57_PSEUL
AccessionPrimary (citable) accession number: G2IV57
Entry history
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: July 9, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)