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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Pseudogulbenkiania sp. (strain NH8B)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei137 – 1371UniRule annotation
Active sitei567 – 5671UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciPSP748280:GHJ9-94-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:NH8B_0094Imported
OrganismiPseudogulbenkiania sp. (strain NH8B)Imported
Taxonomic identifieri748280 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesChromobacteriaceaePseudogulbenkiania
ProteomesiUP000001274: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2IUI6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTDQDKDLPL RASIARLERL LGEVLLEQEG EQVYEEVRAI PADALTGGER
60 70 80 90 100
SRSVLERLSP GATTALVRAC GLYSQLFNIA EDLHHTRRRR AHQIAGSAPQ
110 120 130 140 150
QGSLAGALAR LKQDGVGFGQ LAATLADASV VAVLTAHPTE VQRQSVLDGH
160 170 180 190 200
RAVRKFLSQL NSPELTPEEE SELEAKLKRV MLTLWQTSEI RPFKLSIRDE
210 220 230 240 250
IENGVAYHPL TFFSAMPKLY ERLGRLIADH WEQQVELPSF LRVGSWIGGD
260 270 280 290 300
RDGNPNVDAG VMRHAITRQA EEAFRHYFYE LAGLYRELSL SERHVSVSAA
310 320 330 340 350
VQALSAASPD LAESRREEPY RRALATIEGR LSASAARLGV EARGRWTLGE
360 370 380 390 400
PYADCAALVA DLQALVDSLR EHGSGLLAEG RLGRLLRSLD VFGFFLMPLD
410 420 430 440 450
MRQHAAIHEA VVGELFARAG LEEYVALDEA ARVRVLLREL ATPRLLYSPY
460 470 480 490 500
LTYSAEAEKE LAIFREAARI QREFGVDAIA QSIISNCATV SDILALALLL
510 520 530 540 550
KEAGLIRLDN GIPQASINLV PLFETIADLQ NATLVMDALF ALPWYQQLLK
560 570 580 590 600
SRGMIQEVML GYSDSNKDGG YLTSQWELYL AEQRLVQSFA AAGVKLKLFH
610 620 630 640 650
GRGGSVGRGG GPSYEAIMAQ PAGSVAGRIR ITEQGEVIAS KYSDPDIGAR
660 670 680 690 700
NLEALVAATL EASLSPHACH AVDEEVFNEL SGHAFTAYRE LVETPGFMQY
710 720 730 740 750
FLEATPISAI AKLNIGSRPA SRKSLNSIRD LRAIPWVFSW AQSRVMLPGW
760 770 780 790 800
YGFGSAVSAY LGRHGDEGLA RLQQAYASSP FFQVVLSNME QVMAKGDLNI
810 820 830 840 850
AKGFADLVSD RRLADNLFGR ISEEWHKTQQ AFFAISGQQK LLEKNPTLGR
860 870 880 890 900
SLDIRLPYLD ALNLLQTELL RRLREQPEDA EALYAIHLTI NGISAGLRNS

G
Length:901
Mass (Da):99,183
Last modified:November 16, 2011 - v1
Checksum:iD244AFFF20CD0FAE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012224 Genomic DNA. Translation: BAK74943.1.
RefSeqiWP_014085557.1. NC_016002.1.
YP_004845357.1. NC_016002.1.

Genome annotation databases

EnsemblBacteriaiBAK74943; BAK74943; NH8B_0094.
GeneIDi11154224.
KEGGipse:NH8B_0094.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012224 Genomic DNA. Translation: BAK74943.1.
RefSeqiWP_014085557.1. NC_016002.1.
YP_004845357.1. NC_016002.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAK74943; BAK74943; NH8B_0094.
GeneIDi11154224.
KEGGipse:NH8B_0094.

Phylogenomic databases

KOiK01595.

Enzyme and pathway databases

BioCyciPSP748280:GHJ9-94-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the denitrifying and N(2)O-reducing bacterium Pseudogulbenkiania sp. strain NH8B."
    Ishii S., Tago T., Nishizawa T., Oshima K., Hattori M., Senoo K.
    J. Bacteriol. 193:6395-6396(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NH8BImported.

Entry informationi

Entry nameiG2IUI6_PSEUL
AccessioniPrimary (citable) accession number: G2IUI6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: February 4, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.