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G2I0J7 (G2I0J7_GLUXN) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 10. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Thymidylate synthase ThyX HAMAP-Rule MF_01408
Short name=TS HAMAP-Rule MF_01408
Short name=TSase HAMAP-Rule MF_01408
EC=2.1.1.148 HAMAP-Rule MF_01408
Gene names
Name:thyX HAMAP-Rule MF_01408 EMBL BAK84455.1
Ordered Locus Names:GLX_20430 EMBL BAK84455.1
OrganismGluconacetobacter xylinus (strain NBRC 3288 / BCRC 11682 / LMG 1693) [Complete proteome] [HAMAP]
Taxonomic identifier634177 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Gluconacetobacter ›

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate By similarity. HAMAP-Rule MF_01408

Catalytic activity

5,10-methylenetetrahydrofolate + dUMP + NADPH = dTMP + tetrahydrofolate + NADP+. HAMAP-Rule MF_01408

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP-Rule MF_01408

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01408

Sequence similarities

Belongs to the thymidylate synthase ThyX family. HAMAP-Rule MF_01408

Contains 1 thyX (flavin-dependent thymidylate synthase) domain. HAMAP-Rule MF_01408

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain78 – 300223ThyX By similarity HAMAP-Rule MF_01408

Sequences

Sequence LengthMass (Da)Tools
G2I0J7 [UniParc].

Last modified November 16, 2011. Version 1.
Checksum: 70809CF1FFFB65C0

FASTA35239,701
        10         20         30         40         50         60 
MQGAGPGSHL GEDMAHMVSP ASFAIAMIDT DGTGRHMFST EQKSAIEAAR AGWAQTRRLV 

        70         80         90        100        110        120 
VPAVEDVLYS PIPVLETGFV RAVDYMGGDS GIVQGARVSY GKGTRSTSDD RGLIRYLMRH 

       130        140        150        160        170        180 
RHTSPFELAV LKLHVRAPIF VTRQWFRHRT ASINEYSARY SVLEKEFYFP RPEDIAAQST 

       190        200        210        220        230        240 
NNKQGRADTL PPEQAQQVLD ILRDDAARCY DHYLDLLNED ENGEKRDPDR PAIARELARM 

       250        260        270        280        290        300 
NLPVNIMTQF YWQINLWNLL HFLRLRADSH AQYEIRAYAD AILQIVEKWA PLTFEAFTDY 

       310        320        330        340        350 
MRDAVLLSGP ALRVLRAAMG SGPVDPAGEG LSKREIRELA DMFPEIAPRL RG

« Hide

References

[1]"Complete genome sequence of NBRC 3288, a unique cellulose-nonproducing strain of Gluconacetobacter xylinus isolated from vinegar."
Ogino H., Azuma Y., Hosoyama A., Nakazawa H., Matsutani M., Hasegawa A., Otsuyama K., Matsushita K., Fujita N., Shirai M.
J. Bacteriol. 193:6997-6998(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NBRC 3288 / BCRC 11682 / LMG 1693.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP012159 Genomic DNA. Translation: BAK84455.1.
RefSeqYP_004868825.1. NC_016027.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAK84455; BAK84455; GLX_20430.
GeneID11163639.
KEGGgxy:GLX_20430.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK03465.

Enzyme and pathway databases

BioCycGXYL634177:GHBT-3174-MONOMER.

Family and domain databases

HAMAPMF_01408. ThyX.
InterProIPR003669. Thymidylate_synthase_ThyX.
[Graphical view]
PfamPF02511. Thy1. 1 hit.
[Graphical view]
SUPFAMSSF69796. Thy1. 1 hit.
TIGRFAMsTIGR02170. thyX. 1 hit.
PROSITEPS51331. THYX. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG2I0J7_GLUXN
AccessionPrimary (citable) accession number: G2I0J7
Entry history
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 3, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info