G2HKM8 (G2HKM8_9PROT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydroorotase EMBL BAK69901.1

Gene names

ORF Names:

ABED_0184 EMBL BAK69901.1

Organism

Arcobacter butzleri ED-1 EMBL BAK69901.1

Taxonomic identifier

944546 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Arcobacter › Arcobacter butzleri

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. SAAS SAAS002195
Cofactor	Binds 2 zinc ions per subunit By similarity. SAAS SAAS002195
Pathway	Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. SAAS SAAS002195

Ontologies

Keywords
Biological process	Pyrimidine biosynthesis SAAS SAAS002195
Ligand	Metal-binding SAAS SAAS004721 Zinc SAAS SAAS002195
Molecular function	Hydrolase SAAS SAAS004721
Gene Ontology (GO)
Biological_process	'de novo' UMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway pyrimidine nucleobase biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	dihydroorotase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G2HKM8 [UniParc]. Last modified November 16, 2011. Version 1. Checksum: D434DF1B55E6026E	FASTA	341	38,482
	10 20 30 40 50 60 MSSFKTFELN EPLDMHLHLR DADMLKLVGP LTSKTFSGAL VMPNLVPPIT TKEALLSYKQ 70 80 90 100 110 120 RIKEACKNDQ FEPFVTLFFK NDYSYEFLKD IKDEIIAIKL YPAGITTNSE TGVSSMDIEV 130 140 150 160 170 180 LRPTLESMSK LEIPLCIHGE TNGFVMDREK EFMPIYESIA KAFPKLKIIM EHITTKDAIE 190 200 210 220 230 240 LLDKYDNLFA TVTLHHLLIT LDDVAGGMLQ PHLFCKPIAK TPIDRTALLN AALKAHPKLM 250 260 270 280 290 300 FGSDSAPHPK HKKECCGCAA GVFTSPIALQ VLTQLFEKHN ALENLNAFVS LNAQKIYNLK 310 320 330 340 LDKKIIKLVK KDFVVPAIYE YKEEKVVPMY AGETLSWSLE D

References

[1]	"Complete Genome Sequences of Arcobacter butzleri ED-1 and Arcobacter sp. Strain L, Both Isolated from a Microbial Fuel Cell." Toh H., Sharma V.K., Oshima K., Kondo S., Hattori M., Ward F.B., Free A., Taylor T.D. J. Bacteriol. 193:6411-6412(2011) Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP012047 Genomic DNA. Translation: BAK69901.1.
RefSeq	YP_005537711.1. NC_017187.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAK69901; BAK69901; ABED_0184.
GeneID	12128621.
KEGG	abt:ABED_0184.
Phylogenomic databases
KO	K01465.
Enzyme and pathway databases
UniPathway	UPA00070; UER00117.
Family and domain databases
InterPro	IPR006992. Amidohydro_2. IPR004721. DHOdimr. IPR002195. Dihydroorotase_CS. [Graphical view]
Pfam	PF04909. Amidohydro_2. 1 hit. [Graphical view]
PIRSF	PIRSF001237. DHOdimr. 1 hit.
TIGRFAMs	TIGR00856. pyrC_dimer. 1 hit.
PROSITE	PS00482. DIHYDROOROTASE_1. 1 hit. PS00483. DIHYDROOROTASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G2HKM8_9PROT

Accession

Primary (citable) accession number: G2HKM8

Entry history

Integrated into UniProtKB/TrEMBL:	November 16, 2011
Last sequence update:	November 16, 2011
Last modified:	April 3, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)