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G2HG38

- G2HG38_PANTR

UniProt

G2HG38 - G2HG38_PANTR

Protein
Submitted name:

Egl nine homolog 2

Gene

EGLN2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. iron ion binding Source: InterPro
    2. L-ascorbic acid binding Source: InterPro
    3. oxygen sensor activity Source: Ensembl
    4. peptidyl-proline 4-dioxygenase activity Source: Ensembl

    GO - Biological processi

    1. cell redox homeostasis Source: Ensembl
    2. peptidyl-proline hydroxylation to 4-hydroxy-L-proline Source: Ensembl
    3. positive regulation of protein catabolic process Source: Ensembl
    4. regulation of neuron apoptotic process Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Egl nine homolog 2Imported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:EGLN2Imported
    OrganismiPan troglodytes (Chimpanzee)
    Taxonomic identifieri9598 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
    ProteomesiUP000002277: Chromosome 19

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: Ensembl

    Structurei

    3D structure databases

    ProteinModelPortaliG2HG38.
    SMRiG2HG38. Positions 176-387.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000001936.
    KOiK09592.
    OMAiGGELWPL.
    OrthoDBiEOG7TBC2W.
    TreeFamiTF314595.

    Family and domain databases

    InterProiIPR005123. Oxoglu/Fe-dep_dioxygenase.
    IPR006620. Pro_4_hyd_alph.
    [Graphical view]
    PfamiPF13640. 2OG-FeII_Oxy_3. 1 hit.
    [Graphical view]
    SMARTiSM00702. P4Hc. 1 hit.
    [Graphical view]
    PROSITEiPS51471. FE2OG_OXY. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G2HG38-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDSPCQPQPL SQALPQLPGS SSEPLEPEPG RARMGVESYL PCPLLPSYHC    50
    PGVPSEASAG SGTPRATATS TTASPLRDGF GGQDGGELRP LQSEGAAALV 100
    TKGCQRLAAQ GARPEAPKRK WAEDGGDAPS PSKRPWARQE NQEAEREGGM 150
    SCSCSSGSGE ASAGLMEEAL PSAPERLALD YIVPCMRYYG ICVKDSFLGA 200
    ALGGRVLAEV EALKRGGRLR DGQLVSQRAI PPRSIRGDQI AWVEGHEPGC 250
    RSIGALMAHV DAVIRHCAGR LGSYVINGRT KAMVACYPGN GLGYVRHVDN 300
    PHGDGRCITC IYYLNQNWDV KVHGGLLQIF PEGRPVVANI EPLFDRLLIF 350
    WSDRRNPHEV KPAYATRYAI TVWYFDAKER AAAKDKYQLA SGQKGVQVPV 400
    SQPPTPT 407
    Length:407
    Mass (Da):43,650
    Last modified:November 16, 2011 - v1
    Checksum:iF172E9B0482C9CF3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACZ03119300 Genomic DNA. No translation available.
    AACZ03119301 Genomic DNA. No translation available.
    AK305702 mRNA. Translation: BAK62696.1.
    GABC01008794 mRNA. Translation: JAA02544.1.
    GABE01004764 mRNA. Translation: JAA39975.1.
    RefSeqiNP_001233442.1. NM_001246513.1.

    Genome annotation databases

    EnsembliENSPTRT00000020431; ENSPTRP00000044177; ENSPTRG00000011010.
    GeneIDi456049.
    KEGGiptr:456049.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACZ03119300 Genomic DNA. No translation available.
    AACZ03119301 Genomic DNA. No translation available.
    AK305702 mRNA. Translation: BAK62696.1 .
    GABC01008794 mRNA. Translation: JAA02544.1 .
    GABE01004764 mRNA. Translation: JAA39975.1 .
    RefSeqi NP_001233442.1. NM_001246513.1.

    3D structure databases

    ProteinModelPortali G2HG38.
    SMRi G2HG38. Positions 176-387.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSPTRT00000020431 ; ENSPTRP00000044177 ; ENSPTRG00000011010 .
    GeneIDi 456049.
    KEGGi ptr:456049.

    Organism-specific databases

    CTDi 112398.

    Phylogenomic databases

    GeneTreei ENSGT00390000001936.
    KOi K09592.
    OMAi GGELWPL.
    OrthoDBi EOG7TBC2W.
    TreeFami TF314595.

    Miscellaneous databases

    NextBioi 20837257.

    Family and domain databases

    InterProi IPR005123. Oxoglu/Fe-dep_dioxygenase.
    IPR006620. Pro_4_hyd_alph.
    [Graphical view ]
    Pfami PF13640. 2OG-FeII_Oxy_3. 1 hit.
    [Graphical view ]
    SMARTi SM00702. P4Hc. 1 hit.
    [Graphical view ]
    PROSITEi PS51471. FE2OG_OXY. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
      Chimpanzee sequencing and analysis consortium
      Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: TestisImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
    4. "De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
      Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
      Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Adipose stromalImported and Skeletal muscleImported.

    Entry informationi

    Entry nameiG2HG38_PANTR
    AccessioniPrimary (citable) accession number: G2HG38
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3