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G2HG38

- G2HG38_PANTR

UniProt

G2HG38 - G2HG38_PANTR

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Protein
Submitted name:

Egl nine homolog 2

Gene

EGLN2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. L-ascorbic acid binding Source: InterPro
  3. oxygen sensor activity Source: Ensembl
  4. peptidyl-proline 4-dioxygenase activity Source: Ensembl

GO - Biological processi

  1. cell redox homeostasis Source: Ensembl
  2. peptidyl-proline hydroxylation to 4-hydroxy-L-proline Source: Ensembl
  3. positive regulation of protein catabolic process Source: Ensembl
  4. regulation of neuron apoptotic process Source: Ensembl
  5. response to hypoxia Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Egl nine homolog 2Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:EGLN2Imported
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
ProteomesiUP000002277: Chromosome 19

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: Ensembl
Complete GO annotation...

Interactioni

Structurei

3D structure databases

ProteinModelPortaliG2HG38.
SMRiG2HG38. Positions 176-387.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000001936.
InParanoidiG2HG38.
KOiK09592.
OMAiGGELWPL.
OrthoDBiEOG7TBC2W.
TreeFamiTF314595.

Family and domain databases

InterProiIPR005123. Oxoglu/Fe-dep_dioxygenase.
IPR006620. Pro_4_hyd_alph.
[Graphical view]
PfamiPF13640. 2OG-FeII_Oxy_3. 1 hit.
[Graphical view]
SMARTiSM00702. P4Hc. 1 hit.
[Graphical view]
PROSITEiPS51471. FE2OG_OXY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2HG38-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MDSPCQPQPL SQALPQLPGS SSEPLEPEPG RARMGVESYL PCPLLPSYHC
60 70 80 90 100
PGVPSEASAG SGTPRATATS TTASPLRDGF GGQDGGELRP LQSEGAAALV
110 120 130 140 150
TKGCQRLAAQ GARPEAPKRK WAEDGGDAPS PSKRPWARQE NQEAEREGGM
160 170 180 190 200
SCSCSSGSGE ASAGLMEEAL PSAPERLALD YIVPCMRYYG ICVKDSFLGA
210 220 230 240 250
ALGGRVLAEV EALKRGGRLR DGQLVSQRAI PPRSIRGDQI AWVEGHEPGC
260 270 280 290 300
RSIGALMAHV DAVIRHCAGR LGSYVINGRT KAMVACYPGN GLGYVRHVDN
310 320 330 340 350
PHGDGRCITC IYYLNQNWDV KVHGGLLQIF PEGRPVVANI EPLFDRLLIF
360 370 380 390 400
WSDRRNPHEV KPAYATRYAI TVWYFDAKER AAAKDKYQLA SGQKGVQVPV

SQPPTPT
Length:407
Mass (Da):43,650
Last modified:November 16, 2011 - v1
Checksum:iF172E9B0482C9CF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03119300 Genomic DNA. No translation available.
AACZ03119301 Genomic DNA. No translation available.
AK305702 mRNA. Translation: BAK62696.1.
GABC01008794 mRNA. Translation: JAA02544.1.
GABE01004764 mRNA. Translation: JAA39975.1.
RefSeqiNP_001233442.1. NM_001246513.1.

Genome annotation databases

EnsembliENSPTRT00000020431; ENSPTRP00000044177; ENSPTRG00000011010.
GeneIDi456049.
KEGGiptr:456049.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03119300 Genomic DNA. No translation available.
AACZ03119301 Genomic DNA. No translation available.
AK305702 mRNA. Translation: BAK62696.1 .
GABC01008794 mRNA. Translation: JAA02544.1 .
GABE01004764 mRNA. Translation: JAA39975.1 .
RefSeqi NP_001233442.1. NM_001246513.1.

3D structure databases

ProteinModelPortali G2HG38.
SMRi G2HG38. Positions 176-387.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi G2HG38.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPTRT00000020431 ; ENSPTRP00000044177 ; ENSPTRG00000011010 .
GeneIDi 456049.
KEGGi ptr:456049.

Organism-specific databases

CTDi 112398.

Phylogenomic databases

GeneTreei ENSGT00390000001936.
InParanoidi G2HG38.
KOi K09592.
OMAi GGELWPL.
OrthoDBi EOG7TBC2W.
TreeFami TF314595.

Miscellaneous databases

NextBioi 20837257.

Family and domain databases

InterProi IPR005123. Oxoglu/Fe-dep_dioxygenase.
IPR006620. Pro_4_hyd_alph.
[Graphical view ]
Pfami PF13640. 2OG-FeII_Oxy_3. 1 hit.
[Graphical view ]
SMARTi SM00702. P4Hc. 1 hit.
[Graphical view ]
PROSITEi PS51471. FE2OG_OXY. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
    Chimpanzee sequencing and analysis consortium
    Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  4. "De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
    Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
    Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Adipose stromalImported and Skeletal muscleImported.

Entry informationi

Entry nameiG2HG38_PANTR
AccessioniPrimary (citable) accession number: G2HG38
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 26, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3