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Protein
Submitted name:

Glutathione S-transferase Mu 3

Gene

GSTM3

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. glutathione binding Source: Ensembl
  2. glutathione transferase activity Source: Ensembl

GO - Biological processi

  1. cellular detoxification of nitrogen compound Source: Ensembl
  2. glutathione metabolic process Source: Ensembl
  3. nitrobenzene metabolic process Source: Ensembl
  4. response to estrogen Source: Ensembl
  5. xenobiotic catabolic process Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione S-transferase Mu 3Imported
Submitted name:
Glutathione S-transferase mu 3 (Brain)Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:GSTM3Imported
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
ProteomesiUP000002277 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
  3. nucleus Source: Ensembl
  4. sperm fibrous sheath Source: Ensembl
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliG2HFY3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GST superfamily.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00550000074559.
InParanoidiG2HFY3.
KOiK00799.
OMAiMSCESSM.
OrthoDBiEOG7KH9M3.
TreeFamiTF353040.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR003081. GST_mu.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
PRINTSiPR01267. GSTRNSFRASEM.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2HFY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCESSMVLG YWDIRGLAHA IRLLLEFTDT SYEEKRYTCG EAPDYDRSQW
60 70 80 90 100
LDVKFKLDLD FPNLPYLLDG KNKITQSNAI LRYIARKHNM CGETEEEKIR
110 120 130 140 150
VDIIENQVMD FRTQLIRLCY SSDHEKLKPQ YLEELPGQLK QFSMFLGKFS
160 170 180 190 200
WFAGEKLTFV DFLTYDILDQ NRIFDPKCLD EFPNLKAFMC RFEALEKIAA
210 220
YLQSDQFFKM PINNKMAQWG NKPVC
Length:225
Mass (Da):26,604
Last modified:November 15, 2011 - v1
Checksum:i790F87D1ECEF5396
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03006994 Genomic DNA. No translation available.
AK305647 mRNA. Translation: BAK62641.1.
GABC01008753 mRNA. Translation: JAA02585.1.
RefSeqiNP_001233497.1. NM_001246568.1.
XP_009427417.1. XM_009429142.1.

Genome annotation databases

EnsembliENSPTRT00000001999; ENSPTRP00000001838; ENSPTRG00000001063.
GeneIDi457128.
KEGGiptr:457128.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03006994 Genomic DNA. No translation available.
AK305647 mRNA. Translation: BAK62641.1.
GABC01008753 mRNA. Translation: JAA02585.1.
RefSeqiNP_001233497.1. NM_001246568.1.
XP_009427417.1. XM_009429142.1.

3D structure databases

ProteinModelPortaliG2HFY3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000001999; ENSPTRP00000001838; ENSPTRG00000001063.
GeneIDi457128.
KEGGiptr:457128.

Organism-specific databases

CTDi2947.

Phylogenomic databases

GeneTreeiENSGT00550000074559.
InParanoidiG2HFY3.
KOiK00799.
OMAiMSCESSM.
OrthoDBiEOG7KH9M3.
TreeFamiTF353040.

Miscellaneous databases

NextBioi20838001.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR003081. GST_mu.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
PRINTSiPR01267. GSTRNSFRASEM.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
    Chimpanzee sequencing and analysis consortium
    Nature 437:69-87(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.
  3. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  4. "De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
    Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
    Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Adipose stromalImported.

Entry informationi

Entry nameiG2HFY3_PANTR
AccessioniPrimary (citable) accession number: G2HFY3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 15, 2011
Last sequence update: November 15, 2011
Last modified: March 31, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.