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Protein

Glutathione S-transferase

Gene

GSTM3

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferaseUniRule annotation (EC:2.5.1.18UniRule annotation)
Gene namesi
Name:GSTM3Imported
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSPTRG00000001063.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000001838.

Structurei

3D structure databases

ProteinModelPortaliG2HFY3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 92GST N-terminalInterPro annotationAdd BLAST88
Domaini94 – 212GST C-terminalInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the GST superfamily. Mu family.UniRule annotation
Contains 1 GST C-terminal domain.UniRule annotation
Contains 1 GST N-terminal domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IN5J. Eukaryota.
ENOG4110YU0. LUCA.
GeneTreeiENSGT00550000074559.
KOiK00799.
OMAiQVMDFRM.
OrthoDBiEOG091G0K2E.
TreeFamiTF353040.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR003081. GST_mu.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
PRINTSiPR01267. GSTRNSFRASEM.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G2HFY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCESSMVLG YWDIRGLAHA IRLLLEFTDT SYEEKRYTCG EAPDYDRSQW
60 70 80 90 100
LDVKFKLDLD FPNLPYLLDG KNKITQSNAI LRYIARKHNM CGETEEEKIR
110 120 130 140 150
VDIIENQVMD FRTQLIRLCY SSDHEKLKPQ YLEELPGQLK QFSMFLGKFS
160 170 180 190 200
WFAGEKLTFV DFLTYDILDQ NRIFDPKCLD EFPNLKAFMC RFEALEKIAA
210 220
YLQSDQFFKM PINNKMAQWG NKPVC
Length:225
Mass (Da):26,604
Last modified:November 16, 2011 - v1
Checksum:i790F87D1ECEF5396
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03006994 Genomic DNA. No translation available.
AK305647 mRNA. Translation: BAK62641.1.
GABC01008753 mRNA. Translation: JAA02585.1.
RefSeqiNP_001233497.1. NM_001246568.1.
XP_009427417.1. XM_009429142.1.
XP_016781448.1. XM_016925959.1.

Genome annotation databases

EnsembliENSPTRT00000001999; ENSPTRP00000001838; ENSPTRG00000001063.
GeneIDi107968137.
457128.
KEGGiptr:457128.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03006994 Genomic DNA. No translation available.
AK305647 mRNA. Translation: BAK62641.1.
GABC01008753 mRNA. Translation: JAA02585.1.
RefSeqiNP_001233497.1. NM_001246568.1.
XP_009427417.1. XM_009429142.1.
XP_016781448.1. XM_016925959.1.

3D structure databases

ProteinModelPortaliG2HFY3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000001838.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000001999; ENSPTRP00000001838; ENSPTRG00000001063.
GeneIDi107968137.
457128.
KEGGiptr:457128.

Organism-specific databases

CTDi2947.

Phylogenomic databases

eggNOGiENOG410IN5J. Eukaryota.
ENOG4110YU0. LUCA.
GeneTreeiENSGT00550000074559.
KOiK00799.
OMAiQVMDFRM.
OrthoDBiEOG091G0K2E.
TreeFamiTF353040.

Gene expression databases

BgeeiENSPTRG00000001063.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR003081. GST_mu.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
PRINTSiPR01267. GSTRNSFRASEM.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiG2HFY3_PANTR
AccessioniPrimary (citable) accession number: G2HFY3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 2, 2016
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.