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Protein
Submitted name:

Serum albumin

Gene

ALB

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei264BilirubinUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Serum albuminImported
Gene namesi
Name:ALBImported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Chromosome 15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedPROSITE-ProRule annotation

Pathology & Biotechi

Protein family/group databases

Allergomei759 Ory c 6

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500342413919 – 608Sequence analysisAdd BLAST590

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi32 ↔ 78PROSITE-ProRule annotation
Disulfide bondi77 ↔ 86UniRule annotationCombined sources
Disulfide bondi99 ↔ 115UniRule annotationCombined sources
Disulfide bondi114 ↔ 125UniRule annotationCombined sources
Disulfide bondi148 ↔ 193UniRule annotationCombined sources
Disulfide bondi192 ↔ 201UniRule annotationCombined sources
Disulfide bondi224 ↔ 270UniRule annotationCombined sources
Disulfide bondi269 ↔ 277UniRule annotationCombined sources
Disulfide bondi289 ↔ 303UniRule annotationCombined sources
Disulfide bondi302 ↔ 313UniRule annotationCombined sources
Disulfide bondi340 ↔ 385UniRule annotationCombined sources
Disulfide bondi384 ↔ 393UniRule annotationCombined sources
Disulfide bondi416 ↔ 462UniRule annotationCombined sources
Disulfide bondi461 ↔ 472UniRule annotationCombined sources
Disulfide bondi461 ↔ 469PROSITE-ProRule annotation
Disulfide bondi485 ↔ 501UniRule annotationCombined sources
Disulfide bondi500 ↔ 511UniRule annotationCombined sources
Disulfide bondi538 ↔ 583UniRule annotationCombined sources
Disulfide bondi582 ↔ 591UniRule annotationCombined sources

Keywords - PTMi

Disulfide bondUniRule annotation

Expressioni

Gene expression databases

BgeeiENSOCUG00000016287

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4F5VX-ray2.27A25-608[»]
4PO0X-ray2.73A25-608[»]
SMRiG1U9S2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 211AlbuminInterPro annotationAdd BLAST193
Domaini212 – 403AlbuminInterPro annotationAdd BLAST192
Domaini404 – 601AlbuminInterPro annotationAdd BLAST198

Sequence similaritiesi

Belongs to the ALB/AFP/VDB family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IIRZ Eukaryota
ENOG410Z40H LUCA
GeneTreeiENSGT00390000000113
OMAiKTCVADE
OrthoDBiEOG091G0F5F
TreeFamiTF335561

Family and domain databases

CDDicd00015 ALBUMIN, 3 hits
InterProiView protein in InterPro
IPR000264 ALB/AFP/VDB
IPR020858 Serum_albumin-like
IPR021177 Serum_albumin/AFP/Afamin
IPR020857 Serum_albumin_CS
IPR014760 Serum_albumin_N
PANTHERiPTHR11385 PTHR11385, 1 hit
PfamiView protein in Pfam
PF00273 Serum_albumin, 3 hits
PIRSFiPIRSF002520 Serum_albumin_subgroup, 1 hit
PRINTSiPR00803 AFETOPROTEIN
PR00802 SERUMALBUMIN
SMARTiView protein in SMART
SM00103 ALBUMIN, 3 hits
SUPFAMiSSF48552 SSF48552, 3 hits
PROSITEiView protein in PROSITE
PS00212 ALBUMIN_1, 2 hits
PS51438 ALBUMIN_2, 3 hits

Sequencei

Sequence statusi: Complete.

G1U9S2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWVTFISLL FLFSSAYSRG VFRREAHKSE IAHRFNDVGE EHFIGLVLIT
60 70 80 90 100
FSQYLQKCPY EEHAKLVKEV TDLAKACVAD ESAANCDKSL HDIFGDKICA
110 120 130 140 150
LPSLRDTYGD VADCCEKKEP ERNECFLHHK DDKPDLPPFA RPEADVLCKA
160 170 180 190 200
FHDDEKAFFG HYLYEVARRH PYFYAPELLY YAQKYKAILT ECCEAADKGA
210 220 230 240 250
CLTPKLDALK EKALISAAQE RLRCASIQKF GDRAYKAWAL VRLSQRFPKA
260 270 280 290 300
DFTDISKIVT DLTKVHKECC HGDLLECADD RADLAKYMCE HQETISSHLK
310 320 330 340 350
ECCDKPILEK AHCIYGLHND ETPAGLPAVA EEFVEDKDVC KNYEEAKDLF
360 370 380 390 400
LGKFLYEYSR RHPDYSVVLL LRLGKAYEAT LKKCCATDDP HACYAKVLDE
410 420 430 440 450
FQPLVDEPKN LVKQNCELYE QLGDYNFQNA LLVRYTKKVP QVSTPTLVEI
460 470 480 490 500
SRSLGKVGSK CCKHPEAERL PCVEDYLSVV LNRLCVLHEK TPVSEKVTKC
510 520 530 540 550
CSESLVDRRP CFSALGPDET YVPKEFNAET FTFHADICTL PETERKIKKQ
560 570 580 590 600
TALVELVKHK PHATNDQLKT VVGEFTALLD KCCSAEDKEA CFAVEGPKLV

ESSKATLG
Length:608
Mass (Da):68,965
Last modified:October 19, 2011 - v1
Checksum:iC24CA502C1801BCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02023015 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSOCUT00000016292; ENSOCUP00000014006; ENSOCUG00000016287

Similar proteinsi

Entry informationi

Entry nameiG1U9S2_RABIT
AccessioniPrimary (citable) accession number: G1U9S2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: May 23, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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