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Protein
Submitted name:

Serum albumin

Gene

ALB

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Serum albuminImported
Gene namesi
Name:ALBImported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
ProteomesiUP000001811 Componenti: Chromosome 15

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Protein family/group databases

Allergomei759. Ory c 6.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi77 ↔ 86Combined sources
Disulfide bondi99 ↔ 115Combined sources
Disulfide bondi114 ↔ 125Combined sources
Disulfide bondi148 ↔ 193Combined sources
Disulfide bondi192 ↔ 201Combined sources
Disulfide bondi224 ↔ 270Combined sources
Disulfide bondi269 ↔ 277Combined sources
Disulfide bondi289 ↔ 303Combined sources
Disulfide bondi302 ↔ 313Combined sources
Disulfide bondi340 ↔ 385Combined sources
Disulfide bondi384 ↔ 393Combined sources
Disulfide bondi416 ↔ 462Combined sources
Disulfide bondi461 ↔ 472Combined sources
Disulfide bondi485 ↔ 501Combined sources
Disulfide bondi500 ↔ 511Combined sources
Disulfide bondi538 ↔ 583Combined sources
Disulfide bondi582 ↔ 591Combined sources

Interactioni

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000014006.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4F5VX-ray2.27A25-608[»]
4PO0X-ray2.73A25-608[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000000113.
OMAiNRLCVLH.
OrthoDBiEOG7S4X5C.
TreeFamiTF335561.

Family and domain databases

InterProiIPR000264. ALB/AFP/VDB.
IPR020858. Serum_albumin-like.
IPR021177. Serum_albumin/AFP/Afamin.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
[Graphical view]
PfamiPF00273. Serum_albumin. 3 hits.
[Graphical view]
PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTSiPR00803. AFETOPROTEIN.
PR00802. SERUMALBUMIN.
SMARTiSM00103. ALBUMIN. 3 hits.
[Graphical view]
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiPS00212. ALBUMIN_1. 3 hits.
PS51438. ALBUMIN_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G1U9S2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWVTFISLL FLFSSAYSRG VFRREAHKSE IAHRFNDVGE EHFIGLVLIT
60 70 80 90 100
FSQYLQKCPY EEHAKLVKEV TDLAKACVAD ESAANCDKSL HDIFGDKICA
110 120 130 140 150
LPSLRDTYGD VADCCEKKEP ERNECFLHHK DDKPDLPPFA RPEADVLCKA
160 170 180 190 200
FHDDEKAFFG HYLYEVARRH PYFYAPELLY YAQKYKAILT ECCEAADKGA
210 220 230 240 250
CLTPKLDALK EKALISAAQE RLRCASIQKF GDRAYKAWAL VRLSQRFPKA
260 270 280 290 300
DFTDISKIVT DLTKVHKECC HGDLLECADD RADLAKYMCE HQETISSHLK
310 320 330 340 350
ECCDKPILEK AHCIYGLHND ETPAGLPAVA EEFVEDKDVC KNYEEAKDLF
360 370 380 390 400
LGKFLYEYSR RHPDYSVVLL LRLGKAYEAT LKKCCATDDP HACYAKVLDE
410 420 430 440 450
FQPLVDEPKN LVKQNCELYE QLGDYNFQNA LLVRYTKKVP QVSTPTLVEI
460 470 480 490 500
SRSLGKVGSK CCKHPEAERL PCVEDYLSVV LNRLCVLHEK TPVSEKVTKC
510 520 530 540 550
CSESLVDRRP CFSALGPDET YVPKEFNAET FTFHADICTL PETERKIKKQ
560 570 580 590 600
TALVELVKHK PHATNDQLKT VVGEFTALLD KCCSAEDKEA CFAVEGPKLV

ESSKATLG
Length:608
Mass (Da):68,965
Last modified:October 19, 2011 - v1
Checksum:iC24CA502C1801BCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02023015 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSOCUT00000016292; ENSOCUP00000014006; ENSOCUG00000016287.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02023015 Genomic DNA. No translation available.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4F5VX-ray2.27A25-608[»]
4PO0X-ray2.73A25-608[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000014006.

Protein family/group databases

Allergomei759. Ory c 6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOCUT00000016292; ENSOCUP00000014006; ENSOCUG00000016287.

Phylogenomic databases

GeneTreeiENSGT00390000000113.
OMAiNRLCVLH.
OrthoDBiEOG7S4X5C.
TreeFamiTF335561.

Family and domain databases

InterProiIPR000264. ALB/AFP/VDB.
IPR020858. Serum_albumin-like.
IPR021177. Serum_albumin/AFP/Afamin.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
[Graphical view]
PfamiPF00273. Serum_albumin. 3 hits.
[Graphical view]
PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTSiPR00803. AFETOPROTEIN.
PR00802. SERUMALBUMIN.
SMARTiSM00103. ALBUMIN. 3 hits.
[Graphical view]
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiPS00212. ALBUMIN_1. 3 hits.
PS51438. ALBUMIN_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome Sequence of Oryctolagus cuniculus (European rabbit)."
    The Genome Sequencing Platform
    Di Palma F., Heiman D., Young S., Gnerre S., Johnson J., Lander E.S., Lindblad-Toh K.
    Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThorbeckeImported.
  2. "A high-resolution map of human evolutionary constraint using 29 mammals."
    Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.
    , Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.
    Nature 478:476-482(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThorbeckeImported.
  3. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: ThorbeckeImported.
  4. "Structures of bovine, equine and leporine serum albumin."
    Bujacz A.
    Acta Crystallogr. D 68:1278-1289(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.27 ANGSTROMS) OF 25-608, DISULFIDE BONDS.
  5. "Structural studies of bovine, equine, and leporine serum albumin complexes with naproxen."
    Bujacz A., Zielinski K., Sekula B.
    Proteins 82:2199-2208(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.73 ANGSTROMS) OF 25-608, DISULFIDE BONDS.

Entry informationi

Entry nameiG1U9S2_RABIT
AccessioniPrimary (citable) accession number: G1U9S2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 24, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.