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G1U9S2

- G1U9S2_RABIT

UniProt

G1U9S2 - G1U9S2_RABIT

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Protein
Submitted name:

Serum albumin

Gene

ALB

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: Ensembl
  2. fatty acid binding Source: Ensembl
  3. oxygen binding Source: Ensembl
  4. pyridoxal phosphate binding Source: Ensembl
  5. toxic substance binding Source: Ensembl

GO - Biological processi

  1. cellular response to starvation Source: Ensembl
  2. hemolysis by symbiont of host erythrocytes Source: Ensembl
  3. maintenance of mitochondrion location Source: Ensembl
  4. negative regulation of apoptotic process Source: Ensembl
  5. retina homeostasis Source: Ensembl
  6. transport Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Serum albuminImported
Gene namesi
Name:ALBImported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
ProteomesiUP000001811: Chromosome 15

Subcellular locationi

GO - Cellular componenti

  1. blood microparticle Source: Ensembl
  2. cytoplasm Source: Ensembl
  3. extracellular vesicular exosome Source: Ensembl
  4. nucleus Source: Ensembl
  5. protein complex Source: Ensembl
Complete GO annotation...

Pathology & Biotechi

Protein family/group databases

Allergomei759. Ory c 6.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4F5VX-ray2.27A25-608[»]
4PO0X-ray2.73A25-608[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000000113.
OMAiNCDKSLH.
OrthoDBiEOG7S4X5C.
TreeFamiTF335561.

Family and domain databases

InterProiIPR000264. ALB/AFP/VDB.
IPR001703. Alpha-fetoprotein.
IPR020858. Serum_albumin-like.
IPR021177. Serum_albumin/AFP.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
[Graphical view]
PfamiPF00273. Serum_albumin. 3 hits.
[Graphical view]
PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTSiPR00803. AFETOPROTEIN.
PR00802. SERUMALBUMIN.
SMARTiSM00103. ALBUMIN. 3 hits.
[Graphical view]
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiPS00212. ALBUMIN_1. 3 hits.
PS51438. ALBUMIN_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G1U9S2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKWVTFISLL FLFSSAYSRG VFRREAHKSE IAHRFNDVGE EHFIGLVLIT
60 70 80 90 100
FSQYLQKCPY EEHAKLVKEV TDLAKACVAD ESAANCDKSL HDIFGDKICA
110 120 130 140 150
LPSLRDTYGD VADCCEKKEP ERNECFLHHK DDKPDLPPFA RPEADVLCKA
160 170 180 190 200
FHDDEKAFFG HYLYEVARRH PYFYAPELLY YAQKYKAILT ECCEAADKGA
210 220 230 240 250
CLTPKLDALK EKALISAAQE RLRCASIQKF GDRAYKAWAL VRLSQRFPKA
260 270 280 290 300
DFTDISKIVT DLTKVHKECC HGDLLECADD RADLAKYMCE HQETISSHLK
310 320 330 340 350
ECCDKPILEK AHCIYGLHND ETPAGLPAVA EEFVEDKDVC KNYEEAKDLF
360 370 380 390 400
LGKFLYEYSR RHPDYSVVLL LRLGKAYEAT LKKCCATDDP HACYAKVLDE
410 420 430 440 450
FQPLVDEPKN LVKQNCELYE QLGDYNFQNA LLVRYTKKVP QVSTPTLVEI
460 470 480 490 500
SRSLGKVGSK CCKHPEAERL PCVEDYLSVV LNRLCVLHEK TPVSEKVTKC
510 520 530 540 550
CSESLVDRRP CFSALGPDET YVPKEFNAET FTFHADICTL PETERKIKKQ
560 570 580 590 600
TALVELVKHK PHATNDQLKT VVGEFTALLD KCCSAEDKEA CFAVEGPKLV

ESSKATLG
Length:608
Mass (Da):68,965
Last modified:October 19, 2011 - v1
Checksum:iC24CA502C1801BCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02023015 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSOCUT00000016292; ENSOCUP00000014006; ENSOCUG00000016287.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02023015 Genomic DNA. No translation available.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4F5V X-ray 2.27 A 25-608 [» ]
4PO0 X-ray 2.73 A 25-608 [» ]
ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 759. Ory c 6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSOCUT00000016292 ; ENSOCUP00000014006 ; ENSOCUG00000016287 .

Phylogenomic databases

GeneTreei ENSGT00390000000113.
OMAi NCDKSLH.
OrthoDBi EOG7S4X5C.
TreeFami TF335561.

Family and domain databases

InterProi IPR000264. ALB/AFP/VDB.
IPR001703. Alpha-fetoprotein.
IPR020858. Serum_albumin-like.
IPR021177. Serum_albumin/AFP.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
[Graphical view ]
Pfami PF00273. Serum_albumin. 3 hits.
[Graphical view ]
PIRSFi PIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTSi PR00803. AFETOPROTEIN.
PR00802. SERUMALBUMIN.
SMARTi SM00103. ALBUMIN. 3 hits.
[Graphical view ]
SUPFAMi SSF48552. SSF48552. 3 hits.
PROSITEi PS00212. ALBUMIN_1. 3 hits.
PS51438. ALBUMIN_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome Sequence of Oryctolagus cuniculus (European rabbit)."
    The Genome Sequencing Platform
    Di Palma F., Heiman D., Young S., Gnerre S., Johnson J., Lander E.S., Lindblad-Toh K.
    Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThorbeckeImported.
  2. "A high-resolution map of human evolutionary constraint using 29 mammals."
    Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.
    , Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.
    Nature 478:476-482(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThorbeckeImported.
  3. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: ThorbeckeImported.
  4. "Structures of bovine, equine and leporine serum albumin."
    Bujacz A.
    Acta Crystallogr. D 68:1278-1289(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.27 ANGSTROMS) OF 25-608, ACTIVE SITE.
  5. "Structural studies of bovine, equine, and leporine serum albumin complexes with naproxen."
    Bujacz A., Zielinski K., Sekula B.
    Proteins 82:2199-2208(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.73 ANGSTROMS) OF 25-608, ACTIVE SITE.

Entry informationi

Entry nameiG1U9S2_RABIT
AccessioniPrimary (citable) accession number: G1U9S2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 26, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3