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G1U9S2

- G1U9S2_RABIT

UniProt

G1U9S2 - G1U9S2_RABIT

Protein
Submitted name:

Serum albumin

Gene

ALB

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei174 – 1741Acetate 1Imported
    Binding sitei223 – 2231Acetate 2Imported
    Binding sitei235 – 2351Acetate 2Imported
    Binding sitei281 – 2811Acetate 1Imported

    GO - Molecular functioni

    1. DNA binding Source: Ensembl
    2. fatty acid binding Source: Ensembl
    3. oxygen binding Source: Ensembl
    4. pyridoxal phosphate binding Source: Ensembl
    5. toxic substance binding Source: Ensembl

    GO - Biological processi

    1. cellular response to starvation Source: Ensembl
    2. hemolysis by symbiont of host erythrocytes Source: Ensembl
    3. maintenance of mitochondrion location Source: Ensembl
    4. negative regulation of apoptotic process Source: Ensembl
    5. transport Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Serum albuminImported
    Gene namesi
    Name:ALBImported
    OrganismiOryctolagus cuniculus (Rabbit)Imported
    Taxonomic identifieri9986 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
    ProteomesiUP000001811: Chromosome 15

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. extracellular space Source: Ensembl
    3. extracellular vesicular exosome Source: Ensembl
    4. protein complex Source: Ensembl

    Pathology & Biotechi

    Protein family/group databases

    Allergomei759. Ory c 6.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4F5VX-ray2.27A25-608[»]
    4PO0X-ray2.73A25-608[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000000113.
    OMAiNCDKSLH.
    OrthoDBiEOG7S4X5C.
    TreeFamiTF335561.

    Family and domain databases

    InterProiIPR000264. ALB/AFP/VDB.
    IPR001703. Alpha-fetoprotein.
    IPR020858. Serum_albumin-like.
    IPR021177. Serum_albumin/AFP.
    IPR020857. Serum_albumin_CS.
    IPR014760. Serum_albumin_N.
    [Graphical view]
    PfamiPF00273. Serum_albumin. 3 hits.
    [Graphical view]
    PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
    PRINTSiPR00803. AFETOPROTEIN.
    PR00802. SERUMALBUMIN.
    SMARTiSM00103. ALBUMIN. 3 hits.
    [Graphical view]
    SUPFAMiSSF48552. SSF48552. 3 hits.
    PROSITEiPS00212. ALBUMIN_1. 3 hits.
    PS51438. ALBUMIN_2. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G1U9S2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKWVTFISLL FLFSSAYSRG VFRREAHKSE IAHRFNDVGE EHFIGLVLIT    50
    FSQYLQKCPY EEHAKLVKEV TDLAKACVAD ESAANCDKSL HDIFGDKICA 100
    LPSLRDTYGD VADCCEKKEP ERNECFLHHK DDKPDLPPFA RPEADVLCKA 150
    FHDDEKAFFG HYLYEVARRH PYFYAPELLY YAQKYKAILT ECCEAADKGA 200
    CLTPKLDALK EKALISAAQE RLRCASIQKF GDRAYKAWAL VRLSQRFPKA 250
    DFTDISKIVT DLTKVHKECC HGDLLECADD RADLAKYMCE HQETISSHLK 300
    ECCDKPILEK AHCIYGLHND ETPAGLPAVA EEFVEDKDVC KNYEEAKDLF 350
    LGKFLYEYSR RHPDYSVVLL LRLGKAYEAT LKKCCATDDP HACYAKVLDE 400
    FQPLVDEPKN LVKQNCELYE QLGDYNFQNA LLVRYTKKVP QVSTPTLVEI 450
    SRSLGKVGSK CCKHPEAERL PCVEDYLSVV LNRLCVLHEK TPVSEKVTKC 500
    CSESLVDRRP CFSALGPDET YVPKEFNAET FTFHADICTL PETERKIKKQ 550
    TALVELVKHK PHATNDQLKT VVGEFTALLD KCCSAEDKEA CFAVEGPKLV 600
    ESSKATLG 608
    Length:608
    Mass (Da):68,965
    Last modified:October 19, 2011 - v1
    Checksum:iC24CA502C1801BCE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAGW02023015 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSOCUT00000016292; ENSOCUP00000014006; ENSOCUG00000016287.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAGW02023015 Genomic DNA. No translation available.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4F5V X-ray 2.27 A 25-608 [» ]
    4PO0 X-ray 2.73 A 25-608 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 759. Ory c 6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSOCUT00000016292 ; ENSOCUP00000014006 ; ENSOCUG00000016287 .

    Phylogenomic databases

    GeneTreei ENSGT00390000000113.
    OMAi NCDKSLH.
    OrthoDBi EOG7S4X5C.
    TreeFami TF335561.

    Family and domain databases

    InterProi IPR000264. ALB/AFP/VDB.
    IPR001703. Alpha-fetoprotein.
    IPR020858. Serum_albumin-like.
    IPR021177. Serum_albumin/AFP.
    IPR020857. Serum_albumin_CS.
    IPR014760. Serum_albumin_N.
    [Graphical view ]
    Pfami PF00273. Serum_albumin. 3 hits.
    [Graphical view ]
    PIRSFi PIRSF002520. Serum_albumin_subgroup. 1 hit.
    PRINTSi PR00803. AFETOPROTEIN.
    PR00802. SERUMALBUMIN.
    SMARTi SM00103. ALBUMIN. 3 hits.
    [Graphical view ]
    SUPFAMi SSF48552. SSF48552. 3 hits.
    PROSITEi PS00212. ALBUMIN_1. 3 hits.
    PS51438. ALBUMIN_2. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome Sequence of Oryctolagus cuniculus (European rabbit)."
      The Genome Sequencing Platform
      Di Palma F., Heiman D., Young S., Gnerre S., Johnson J., Lander E.S., Lindblad-Toh K.
      Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ThorbeckeImported.
    2. "A high-resolution map of human evolutionary constraint using 29 mammals."
      Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.
      , Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.
      Nature 478:476-482(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ThorbeckeImported.
    3. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: ThorbeckeImported.
    4. "Structures of bovine, equine and leporine serum albumin."
      Bujacz A.
      Acta Crystallogr. D 68:1278-1289(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.27 ANGSTROMS) OF 25-608.
    5. "Structural studies of bovine, equine, and leporine serum albumin complexes with naproxen."
      Bujacz A., Zielinski K., Sekula B.
      Proteins 0:0-0(2014) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.73 ANGSTROMS) OF 25-608.

    Entry informationi

    Entry nameiG1U9S2_RABIT
    AccessioniPrimary (citable) accession number: G1U9S2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3