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Protein
Submitted name:

Calpain 5

Gene

CAPN5

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei204PROSITE-ProRule annotation1
Active sitei375PROSITE-ProRule annotation1
Active sitei407PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteasePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Calpain 5Imported
Gene namesi
Name:CAPN5Imported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Chromosome 1

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSOCUG00000025830

Interactioni

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000024215

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini149 – 466Calpain catalyticInterPro annotationAdd BLAST318

Sequence similaritiesi

Belongs to the peptidase C2 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0045 Eukaryota
ENOG410XP0B LUCA
GeneTreeiENSGT00760000118971
InParanoidiG1U496
OMAiRPKDICE
OrthoDBiEOG091G030A
TreeFamiTF314748

Family and domain databases

CDDicd04046 C2_Calpain, 1 hit
cd00214 Calpain_III, 1 hit
cd00044 CysPc, 1 hit
Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR033884 C2_Calpain
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR033883 C2_III
IPR022684 Calpain_cysteine_protease
IPR022682 Calpain_domain_III
IPR022683 Calpain_III
IPR036213 Calpain_III_sf
IPR000169 Pept_cys_AS
IPR001300 Peptidase_C2_calpain_cat
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF01067 Calpain_III, 1 hit
PF00648 Peptidase_C2, 1 hit
PRINTSiPR00704 CALPAIN
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00720 calpain_III, 1 hit
SM00230 CysPc, 1 hit
SUPFAMiSSF49758 SSF49758, 1 hit
PROSITEiView protein in PROSITE
PS50203 CALPAIN_CAT, 1 hit
PS00139 THIOL_PROTEASE_CYS, 1 hit

Sequencei

Sequence statusi: Complete.

G1U496-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPLGQQQAA AGEATSVEPC APGKLVHHLG AGLFRPAPLR PGPAQPSPAG
60 70 80 90 100
LGKTNNSGSV AFPADGSLSP RLILMPWGTE VMSARHCSPG LLLLPPGPSS
110 120 130 140 150
RARDWPPVSG AGAPGARPGP AATMFSCVKA YEEQNYAALK RSCLRRKVLF
160 170 180 190 200
EDPHFPATDD SLYYKATPGP AVRWKRPKDI CEDPRLFVDG ISSHDLHQGQ
210 220 230 240 250
VGNCWFVAAC SSLASRESLW QKVIPDWKEQ EWDPEKPDAY AGIFHFHFWR
260 270 280 290 300
FGEWVDVVID DRLPTVNNQL IYCHSNSRRE FWCALVEKAY AKLAGCYQAL
310 320 330 340 350
DGGNTADALV DFTGGVSEPI DLMEGDFAND EAKRNQLFER MLKVHTRGGL
360 370 380 390 400
ISASIKAVTA ADMEARLACG LVKGHAYAVT DVRKVRLGHG LLAFFKSEKL
410 420 430 440 450
DMIRLRNPWG EREWNGPWSD TSEEWQKVSK SEREKMGVTV QDDGEFWMTF
460 470 480 490 500
EDVCRYFTDI IKCRVLNTSY LSIHKTWEEA RLRGAWTRHE DPRQNRSGGC
510 520 530 540 550
INHKDTFFQN PQYLFDVKKP EDEVLICIQQ RPKRSTRREG KGENLAIGFD
560 570 580 590 600
IYKVEENRQY RMHSLQHKAA SSIYINSRSV FLRTEQPEGR YVIIPTTFEP
610 620 630 640 650
GHTGEFLLRV FTDVPANCRE LRLDEPPHTC WSSLCGYPQQ VTQVHVLGAA
660 670 680 690 700
GLKDSPAGAN SYVIIKCEGE AVRSAVQRGT SAPEYNVKGV FYRKKPGQPV
710 720 730 740 750
TVQIWNHRVL KDEFLGQVQL KADPNDLQAL HTLHLRDRSS RQPSDLPGTV
760
AVRVLSSASL TAV
Length:763
Mass (Da):85,291
Last modified:November 13, 2013 - v2
Checksum:iC47B43FD3187DFA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02008263 Genomic DNA No translation available.
AAGW02008264 Genomic DNA No translation available.
AAGW02008265 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSOCUT00000024355; ENSOCUP00000024215; ENSOCUG00000025830

Similar proteinsi

Entry informationi

Entry nameiG1U496_RABIT
AccessioniPrimary (citable) accession number: G1U496
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: November 13, 2013
Last modified: March 28, 2018
This is version 39 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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