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Protein

40S ribosomal protein S3a

Gene

RPS3A

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May play a role during erythropoiesis through regulation of transcription factor DDIT3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal proteinUniRule annotationSAAS annotation

Keywords - Biological processi

DifferentiationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S3aUniRule annotation
Gene namesi
Name:RPS3AUniRule annotation
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Nucleus UniRule annotation

  • Note: Localized in cytoplasmic mRNP granules containing untranslated mRNAs.UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation, NucleusUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedUniRule annotation

Interactioni

Subunit structurei

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.UniRule annotation

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000018441.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4KZXX-ray7.81B1-264[»]
4KZYX-ray7.01B1-264[»]
4KZZX-ray7.03B1-264[»]
5K0Yelectron microscopy5.80i19-233[»]
SMRiG1TN72.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S3Ae family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1628. Eukaryota.
COG1890. LUCA.
GeneTreeiENSGT00390000018433.
InParanoidiG1TN72.
OMAiNDEDHAY.
OrthoDBiEOG091G0HTU.
TreeFamiTF300037.

Family and domain databases

HAMAPiMF_03122. Ribosomal_S3Ae_euk. 1 hit.
InterProiIPR027500. Ribosomal_S1/3_euk.
IPR001593. Ribosomal_S3Ae.
IPR018281. Ribosomal_S3Ae_CS.
[Graphical view]
PfamiPF01015. Ribosomal_S3Ae. 1 hit.
[Graphical view]
SMARTiSM01397. Ribosomal_S3Ae. 1 hit.
[Graphical view]
PROSITEiPS01191. RIBOSOMAL_S3AE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

G1TN72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVGKNKRLT KGGKKGAKKK VVDPFSKKDW YDVKAPAMFN IRNIGKTLVT
60 70 80 90 100
RTQGTKIASD GLKGRVFEVS LADLQNDEVA FRKFKLITED VQGKNCLTNF
110 120 130 140 150
HGMDLTRDKM CSMVKKWQTM IEAHVDVKTT DGYLLHLFCV GFTKKCNNQI
160 170 180 190 200
RKTSYAQHQQ VRQIRKKMME IMTREVQTND LKEVVNKLIP DSIGKDIEKA
210 220 230 240 250
CQSIYPLHDV FVRKVKMLKK PKFELGKLME LHGEGSSSGK ATGDETGAKV
260
ERADGYEPPV QESV
Length:264
Mass (Da):29,873
Last modified:October 19, 2011 - v1
Checksum:iB812224E085F63CB
GO

Genome annotation databases

EnsembliENSOCUT00000031254; ENSOCUP00000018441; ENSOCUG00000024968.

Cross-referencesi

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4KZXX-ray7.81B1-264[»]
4KZYX-ray7.01B1-264[»]
4KZZX-ray7.03B1-264[»]
5K0Yelectron microscopy5.80i19-233[»]
SMRiG1TN72.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000018441.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOCUT00000031254; ENSOCUP00000018441; ENSOCUG00000024968.

Phylogenomic databases

eggNOGiKOG1628. Eukaryota.
COG1890. LUCA.
GeneTreeiENSGT00390000018433.
InParanoidiG1TN72.
OMAiNDEDHAY.
OrthoDBiEOG091G0HTU.
TreeFamiTF300037.

Family and domain databases

HAMAPiMF_03122. Ribosomal_S3Ae_euk. 1 hit.
InterProiIPR027500. Ribosomal_S1/3_euk.
IPR001593. Ribosomal_S3Ae.
IPR018281. Ribosomal_S3Ae_CS.
[Graphical view]
PfamiPF01015. Ribosomal_S3Ae. 1 hit.
[Graphical view]
SMARTiSM01397. Ribosomal_S3Ae. 1 hit.
[Graphical view]
PROSITEiPS01191. RIBOSOMAL_S3AE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiG1TN72_RABIT
AccessioniPrimary (citable) accession number: G1TN72
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 30, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.