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G1TN72

- G1TN72_RABIT

UniProt

G1TN72 - G1TN72_RABIT

Protein

40S ribosomal protein S3a

Gene

LOC100340708

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    May play a role during erythropoiesis through regulation of transcription factor DDIT3.UniRule annotation

    GO - Molecular functioni

    1. structural constituent of ribosome Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cell differentiation Source: UniProtKB-KW
    2. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal proteinUniRule annotationSAAS annotation

    Keywords - Biological processi

    DifferentiationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S3aUniRule annotation
    Gene namesi
    Name:LOC100340708Imported
    Synonyms:RPS3AUniRule annotation
    OrganismiOryctolagus cuniculus (Rabbit)Imported
    Taxonomic identifieri9986 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
    ProteomesiUP000001811: Unplaced

    Subcellular locationi

    Cytoplasm UniRule annotation. Nucleus UniRule annotation
    Note: Localized in cytoplasmic mRNP granules containing untranslated mRNAs.UniRule annotation

    GO - Cellular componenti

    1. cytosolic small ribosomal subunit Source: UniProtKB-HAMAP
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation, NucleusUniRule annotation

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedUniRule annotation

    Interactioni

    Subunit structurei

    Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.UniRule annotation

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4KZXX-ray7.81B1-264[»]
    4KZYX-ray7.01B1-264[»]
    4KZZX-ray7.03B1-264[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S3Ae family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00390000018433.
    OMAiPERSFRK.
    OrthoDBiEOG7Q5HDW.
    TreeFamiTF300037.

    Family and domain databases

    HAMAPiMF_03122. Ribosomal_S3Ae_euk.
    InterProiIPR027500. Ribosomal_S1/3_euk.
    IPR001593. Ribosomal_S3Ae.
    IPR018281. Ribosomal_S3Ae_CS.
    [Graphical view]
    PfamiPF01015. Ribosomal_S3Ae. 1 hit.
    [Graphical view]
    PROSITEiPS01191. RIBOSOMAL_S3AE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    G1TN72-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVGKNKRLT KGGKKGAKKK VVDPFSKKDW YDVKAPAMFN IRNIGKTLVT    50
    RTQGTKIASD GLKGRVFEVS LADLQNDEVA FRKFKLITED VQGKNCLTNF 100
    HGMDLTRDKM CSMVKKWQTM IEAHVDVKTT DGYLLHLFCV GFTKKCNNQI 150
    RKTSYAQHQQ VRQIRKKMME IMTREVQTND LKEVVNKLIP DSIGKDIEKA 200
    CQSIYPLHDV FVRKVKMLKK PKFELGKLME LHGEGSSSGK ATGDETGAKV 250
    ERADGYEPPV QESV 264
    Length:264
    Mass (Da):29,873
    Last modified:October 19, 2011 - v1
    Checksum:iB812224E085F63CB
    GO

    Sequence databases

    UniGeneiOcu.8137.

    Genome annotation databases

    EnsembliENSOCUT00000031254; ENSOCUP00000018441; ENSOCUG00000024968.

    Cross-referencesi

    Sequence databases

    UniGenei Ocu.8137.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4KZX X-ray 7.81 B 1-264 [» ]
    4KZY X-ray 7.01 B 1-264 [» ]
    4KZZ X-ray 7.03 B 1-264 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSOCUT00000031254 ; ENSOCUP00000018441 ; ENSOCUG00000024968 .

    Phylogenomic databases

    GeneTreei ENSGT00390000018433.
    OMAi PERSFRK.
    OrthoDBi EOG7Q5HDW.
    TreeFami TF300037.

    Family and domain databases

    HAMAPi MF_03122. Ribosomal_S3Ae_euk.
    InterProi IPR027500. Ribosomal_S1/3_euk.
    IPR001593. Ribosomal_S3Ae.
    IPR018281. Ribosomal_S3Ae_CS.
    [Graphical view ]
    Pfami PF01015. Ribosomal_S3Ae. 1 hit.
    [Graphical view ]
    PROSITEi PS01191. RIBOSOMAL_S3AE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome Sequence of Oryctolagus cuniculus (European rabbit)."
      The Genome Sequencing Platform
      Di Palma F., Heiman D., Young S., Gnerre S., Johnson J., Lander E.S., Lindblad-Toh K.
      Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ThorbeckeImported.
    2. "A high-resolution map of human evolutionary constraint using 29 mammals."
      Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.
      , Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.
      Nature 478:476-482(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ThorbeckeImported.
    3. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: ThorbeckeImported.
    4. "The initiation of mammalian protein synthesis and mRNA scanning mechanism."
      Lomakin I.B., Steitz T.A.
      Nature 500:307-311(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (7.01 ANGSTROMS).

    Entry informationi

    Entry nameiG1TN72_RABIT
    AccessioniPrimary (citable) accession number: G1TN72
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3