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Protein

AMP deaminase

Gene

AMPD3

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

AMP + H2O = IMP + NH3.UniRule annotation

Cofactori

Zn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
AMP deaminaseUniRule annotation (EC:3.5.4.6UniRule annotation)
Gene namesi
Name:AMPD3Imported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Chromosome 1

Expressioni

Gene expression databases

BgeeiENSOCUG00000002805.

Interactioni

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000002432.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini361 – 768A_deaminaseInterPro annotationAdd BLAST408

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili100 – 123Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1096. Eukaryota.
COG1816. LUCA.
GeneTreeiENSGT00390000008190.
InParanoidiG1SIC7.
KOiK01490.
OMAiHSLPYPD.
OrthoDBiEOG091G01OU.
TreeFamiTF300439.

Family and domain databases

CDDicd01319. AMPD. 1 hit.
InterProiView protein in InterPro
IPR006650. A/AMP_deam_AS.
IPR001365. A/AMP_deaminase_dom.
IPR006329. AMPD.
IPR029771. AMPD3.
IPR032466. Metal_Hydrolase.
PANTHERiPTHR11359. PTHR11359. 1 hit.
PTHR11359:SF12. PTHR11359:SF12. 1 hit.
PfamiView protein in Pfam
PF00962. A_deaminase. 1 hit.
PIRSFiPIRSF001251. AMP_deaminase_met. 1 hit.
SFLDiSFLDF00063. AMP_deaminase. 1 hit.
SUPFAMiSSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01429. AMP_deaminase. 1 hit.
PROSITEiView protein in PROSITE
PS00485. A_DEAMINASE. 1 hit.

Sequencei

Sequence statusi: Complete.

G1SIC7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSRALPLQP ACRPQPGCLY PDSAQRPAAG GTWPQRASPS AMETPAPGSA
60 70 80 90 100
EMPRQFPKLN ISEVDEQVRL LAEKVFAKVL REEDSKDALS LFTVPEDCPI
110 120 130 140 150
GQKEAKEREL QKELAEQKSL ETAKRKKSFK MIRSQSLSLQ MPTQQDWKGP
160 170 180 190 200
PTASPAMSPA TPVVAGAASQ PAPAPYAMPE YQRVTISGDY CAGITVEDYE
210 220 230 240 250
QAAKSLAKAL MIREKYARLA YHRFPRTTAQ YLGHRRPDVA PPEDGLPDFY
260 270 280 290 300
PPPRPQEDPY CLDDAPPNLG YLVRMQGGIL FVYDNKKMLE RQEPHSLPYP
310 320 330 340 350
DLETYTVDMS HILALITDGP TKTYCHRRLN FLESKFSLHE MLNEMSEFKE
360 370 380 390 400
LKSNPHRDFY NVRKVDTHIH AAACMNQKHL LRFIKHTYQT EPDRTVAEKR
410 420 430 440 450
GRKITLRQVF DSLHMDPYDL TVDSLDVHAG RQTFHRFDKF NSKYNPVGAS
460 470 480 490 500
ELRDLYLKTE NYLGGEYFAR MVKEVARELE ESKYQYSEPR LSIYGRSPEE
510 520 530 540 550
WPNLARWFIQ HKVYSPNMRW IIQVPRIYDI FRSKKLLPNF GKMLENIFLP
560 570 580 590 600
LFKATIDPQD HRELHLFLKY VTGFDSVDDE SKHSDHMFSD KSPSPDIWTS
610 620 630 640 650
EQNPPYSYYL YYMYANIMVL NNLRRERGLS TFLFRPHCGE AGSITHLVAA
660 670 680 690 700
FLTADNISHG LLLKKSPVLQ YLYYLAQIPI AMSPLSNNSL FLEYSKNPLR
710 720 730 740 750
EFLHKGLHVS LSTDDPMQFH YTKEALMEEY AIAAQVWKLS TCDLCEIARN
760 770 780 790 800
SVLQSGLSHQ EKQKFLGQNY YKEGPEGNDI RKTNVAQIRM AFRYETLCNE
810
LSFLSDAMKS EEITALAK
Length:818
Mass (Da):94,099
Last modified:November 13, 2013 - v2
Checksum:i612AF543C3C6C535
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02007866 Genomic DNA. No translation available.
RefSeqiXP_017200847.1. XM_017345358.1.

Genome annotation databases

EnsembliENSOCUT00000002802; ENSOCUP00000002432; ENSOCUG00000002805.
GeneIDi100351884.
KEGGiocu:100351884.

Similar proteinsi

Entry informationi

Entry nameiG1SIC7_RABIT
AccessioniPrimary (citable) accession number: G1SIC7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: November 13, 2013
Last modified: September 27, 2017
This is version 35 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported