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Protein
Submitted name:

Cytochrome P450 family 2 subfamily S member 1

Gene

CYP2S1

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 family 2 subfamily S member 1Imported
Gene namesi
Name:CYP2S1Imported
OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
Taxonomic identifieri61853 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
Proteomesi
  • UP000001073 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei296 – 319HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500342108023 – 563Sequence analysisAdd BLAST541

Interactioni

Protein-protein interaction databases

STRINGi61853.ENSNLEP00000016805.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00880000137861.
InParanoidiG1RU80.
OMAiQLRKFTM.
OrthoDBiEOG091G0BT8.
TreeFamiTF352043.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008067. Cyt_P450_E_grp-I_CYP2A-like.
IPR036396. Cyt_P450_sf.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR01684. EP450ICYP2A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

G1RU80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEATGTWALL LALALLLLLT LALSGTRARG HLPPGPTPLP LLGNLLQLRP
60 70 80 90 100
GALYSGLMRL SKKYGPVFTI YLGPWRPVVV LVGQEAVREA LGGQAEEFSG
110 120 130 140 150
RGTVAMLERT FDGHGVFFSN GERWRQLRKF TMLALRDLGM GKREGEELIQ
160 170 180 190 200
AEARCLLEAF QETEGRPFDP SLLLAQATSN VVCSLLFGLR FSYEDKEFQA
210 220 230 240 250
VVRAAGGTLL GVSSRGGQTY EMFSWFLRPL PGPHKQLLHH ISTLAAFTVQ
260 270 280 290 300
QVQQHQGNLD ASVPTRDLVD AFLLKMAQEE QNPDTEFTNK NMLMTVIYLL
310 320 330 340 350
FAGTMTVSAT VGYTLLLLMK YPHVQKRVRE ELNRELGAGQ APSLGDRIRL
360 370 380 390 400
PYTDAVLHEA QRLLALVPMG IPRTLMRTTR FRGYTLPQGT EVFPLLGSIL
410 420 430 440 450
HDPNIFKHPE EFNPDRFLEA DGRFRKHEAF PFSLGKRVCL GEGLAKAELF
460 470 480 490 500
LFFTTILQAF SLESPCPPGT LSLKPTISGL FNIPPAFQVG MDRVNVSRVY
510 520 530 540 550
TAGSRIYTPA AVFRSLSHGP HTHLTHAAKI YNHTAIHNYK GQKATDALAF
560
HRHKYSPSAI TST
Length:563
Mass (Da):62,459
Last modified:October 19, 2011 - v1
Checksum:i9CEEF9CB169D3E7E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01054888 Genomic DNA. No translation available.
ADFV01054889 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSNLET00000017657; ENSNLEP00000016805; ENSNLEG00000013841.

Similar proteinsi

Entry informationi

Entry nameiG1RU80_NOMLE
AccessioniPrimary (citable) accession number: G1RU80
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: October 25, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported