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Protein
Submitted name:

Adhesion G protein-coupled receptor L2

Gene

ADGRL2

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Adhesion G protein-coupled receptor L2Imported
Gene namesi
Name:ADGRL2Imported
OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
Taxonomic identifieri61853 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
Proteomesi
  • UP000001073 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei845 – 870HelicalSequence analysisAdd BLAST26
Transmembranei882 – 900HelicalSequence analysisAdd BLAST19
Transmembranei906 – 930HelicalSequence analysisAdd BLAST25
Transmembranei951 – 971HelicalSequence analysisAdd BLAST21
Transmembranei991 – 1014HelicalSequence analysisAdd BLAST24
Transmembranei1051 – 1073HelicalSequence analysisAdd BLAST23
Transmembranei1079 – 1102HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500341988326 – 1474Sequence analysisAdd BLAST1449

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi136 ↔ 318PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Interactioni

Protein-protein interaction databases

STRINGi61853.ENSNLEP00000012007.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 130SUEL-type lectinInterPro annotationAdd BLAST90
Domaini135 – 394Olfactomedin-likeInterPro annotationAdd BLAST260
Domaini468 – 525G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST58
Domaini785 – 836GPSInterPro annotationAdd BLAST52
Domaini847 – 1103G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST257

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3545. Eukaryota.
KOG4193. Eukaryota.
KOG4729. Eukaryota.
ENOG410XSD2. LUCA.
GeneTreeiENSGT00900000140800.
InParanoidiG1RFK7.
OMAiYFNANCS.
OrthoDBiEOG091G00GJ.
TreeFamiTF351999.

Family and domain databases

InterProiView protein in InterPro
IPR032471. GAIN_dom_N.
IPR017981. GPCR_2-like.
IPR036445. GPCR_2_extracell_dom_sf.
IPR001879. GPCR_2_extracellular_dom.
IPR003924. GPCR_2_latrophilin.
IPR003334. GPCR_2_latrophilin_rcpt_C.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
IPR031240. Latrophilin-2.
IPR000922. Lectin_gal-bd_dom.
IPR003112. Olfac-like_dom.
PANTHERiPTHR12011:SF61. PTHR12011:SF61. 1 hit.
PfamiView protein in Pfam
PF00002. 7tm_2. 1 hit.
PF16489. GAIN. 1 hit.
PF02140. Gal_Lectin. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF02354. Latrophilin. 1 hit.
PF02191. OLF. 1 hit.
PRINTSiPR00249. GPCRSECRETIN.
PR01444. LATROPHILIN.
SMARTiView protein in SMART
SM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00284. OLF. 1 hit.
SUPFAMiSSF111418. SSF111418. 1 hit.
PROSITEiView protein in PROSITE
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS51132. OLF. 1 hit.
PS50228. SUEL_LECTIN. 1 hit.

Sequencei

Sequence statusi: Complete.

G1RFK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSSGCRMRS LWFIIVISFL PNSEGFSRAA LPFGLVRREL SCEGYSIDLR
60 70 80 90 100
CPGSDVIMIE SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR
110 120 130 140 150
TQCIVITGSD VFPDPCPGTY KYLEVQYECV PYIFVCPGTL KAIVDSPCIY
160 170 180 190 200
EAEQKAGAWC KDPLQAADKI YFMPWTPYRT DTLIEYASLE DFQNSRQTTT
210 220 230 240 250
YKLPNRVDGT GFVVYDGAVF FNKERTRNIV KFDLRTRIKS GEAIINYANY
260 270 280 290 300
HDTSPYRWGG KTDIDLAVDE NGLWVIYATE QNNGMIVISQ LNPYTLRFEA
310 320 330 340 350
TWETVYDKRA ASNAFMICGV LYVVRSVYQD NESETGKNSI DYIYNTRLNR
360 370 380 390 400
GEYVDVPFPN QYQYIAAVDY NPRDNQLYVW NNNFILRYSL EFGPPDPAQV
410 420 430 440 450
PTTAVTITSS AELFKTTVST TSTTSQKGPM STTVAGSQEG SKGTKPPPAV
460 470 480 490 500
STTKIPPVTN IFPLPERFCE ALDSKGIKWP QTQRGMMVER PCPKGTRGTA
510 520 530 540 550
SYLCMISTGT WNPKGPDLSN CTSHWVNQLA QKIRSGENAA SLANELAKHT
560 570 580 590 600
KGPVFAGDVS SSVRLMEQLV DILDAQLQEL KPSEKDSAGR SYNKLQKREK
610 620 630 640 650
TCRAYLKAIV DTVDNLLRPE ALESWKHMNS SEQAHTATML LDTLEEGAFV
660 670 680 690 700
LADNLLEPTR VSMPTENIVL EVAVLSTEGQ IQDFKFPLGI KGAGSSIQLS
710 720 730 740 750
ANTVKQNSRN GLAKLVFIIY RSLGQFLSTE NATIKLGADF IGRNSTIAVN
760 770 780 790 800
SHVISVSINK ESSRVYLTDP VLFTLPHIDP DNYFNANCSF WNYSERTMMG
810 820 830 840 850
YWSTQGCKLV DTNKTRTTCA CSHLTNFAIL MAHREIAYKD GVHELLLTVI
860 870 880 890 900
TWVGIVISLV CLAICIFTFC FFRGLQSDRN TIHKNLCINL FIAEFIFLIG
910 920 930 940 950
IDKTKYAIAC PIFAGLLHFF FLAAFAWMCL EGVQLYLMLV EVFESEYSRK
960 970 980 990 1000
KYYYVAGYLF PATVVGVSAA IDYKSYGTEK ACWLHVDNYF IWSFIGPVTF
1010 1020 1030 1040 1050
IILLNIIFLV ITLCKMVKHS NTLKPDSSRL ENINNYRVCD GYYNTDLPGS
1060 1070 1080 1090 1100
WVLGAFALLC LLGLTWSFGL LFINEETIVM AYLFTIFNAF QGVFIFIFHC
1110 1120 1130 1140 1150
ALQKKVRKEY GKCFRHSYCC GGLPTESPHS SVKASTTRTS ARYSSGTQSR
1160 1170 1180 1190 1200
IRRMWNDTVR KQSESSFISG DINSTSTLNQ GMTGNYLLTN PLLRPHGTNN
1210 1220 1230 1240 1250
PYNTLLAETV VCNAPSAPVF NSPGHSLNNA RDTSAMDTLP LNGNFNNSYS
1260 1270 1280 1290 1300
LRKGDYNDSV QVVDCGLSLN DTAFEKMIIS ELVHNNLRGS SKTHNLELTL
1310 1320 1330 1340 1350
PVKPVIGGSS SEDDAIVADA SSLMHSDNPG LELHHKELKA PLIPQRTHSL
1360 1370 1380 1390 1400
LYQPQKKVKS EGTDSYVSQL TAEGEDHLQS PNRDSLYTSM PNLRDSPYPE
1410 1420 1430 1440 1450
SSPDMEEDLS PSRRSENEDI YYKSMPNLGA GHQLQMCYQI SRGNSDGYII
1460 1470
PINKEGCIPE GDVREGQMQL VTSL
Length:1,474
Mass (Da):165,031
Last modified:October 19, 2011 - v1
Checksum:iFA1A88899B2F4C30
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01189289 Genomic DNA. No translation available.
ADFV01189290 Genomic DNA. No translation available.
ADFV01189291 Genomic DNA. No translation available.
ADFV01189292 Genomic DNA. No translation available.
ADFV01189293 Genomic DNA. No translation available.
ADFV01189294 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSNLET00000012592; ENSNLEP00000012007; ENSNLEG00000009826.

Similar proteinsi

Entry informationi

Entry nameiG1RFK7_NOMLE
AccessioniPrimary (citable) accession number: G1RFK7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 22, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported