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Protein

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

Gene

NDUFA12

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chainUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12UniRule annotation
Gene namesi
Name:NDUFA12Imported
OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
Taxonomic identifieri61853 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
Proteomesi
  • UP000001073 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.UniRule annotation

Protein-protein interaction databases

STRINGi61853.ENSNLEP00000006986.

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFA12 subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3382. Eukaryota.
ENOG4111XVR. LUCA.
GeneTreeiENSGT00390000005848.
InParanoidiG1R1B4.
KOiK11352.
OMAiWHGWIHH.
OrthoDBiEOG091G0XDC.
TreeFamiTF106106.

Family and domain databases

InterProiView protein in InterPro
IPR007763. NDUFA12.
PANTHERiPTHR12910. PTHR12910. 1 hit.
PfamiView protein in Pfam
PF05071. NDUFA12. 1 hit.

Sequencei

Sequence statusi: Complete.

G1R1B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELVQVLKRG LQQITGHGGL RGYLRVFFRT NDARVGTLVG EDKYGNKYYE
60 70 80 90 100
DNKQFFGRHR WVVYTTEMNG KNTFWDVDGS MVPPEWHRWL HSMTDDPPTT
110 120 130 140
KPPTARKFIW TNHKFNVTGT PEQYVPYSTT RKKIQEWIPP STPYK
Length:145
Mass (Da):17,126
Last modified:October 19, 2011 - v1
Checksum:i69470842EFA69717
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01186749 Genomic DNA. No translation available.
ADFV01186750 Genomic DNA. No translation available.
ADFV01186751 Genomic DNA. No translation available.
ADFV01186752 Genomic DNA. No translation available.
ADFV01186753 Genomic DNA. No translation available.
RefSeqiXP_012355740.1. XM_012500286.1.

Genome annotation databases

EnsembliENSNLET00000007333; ENSNLEP00000006986; ENSNLEG00000005766.
GeneIDi100579680.
KEGGinle:100579680.

Similar proteinsi

Entry informationi

Entry nameiG1R1B4_NOMLE
AccessioniPrimary (citable) accession number: G1R1B4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: July 5, 2017
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported