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Protein
Submitted name:

Chromodomain helicase DNA binding protein 4

Gene

CHD4

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Chromodomain helicase DNA binding protein 4Imported
Gene namesi
Name:CHD4Imported
OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
Taxonomic identifieri61853 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
Proteomesi
  • UP000001073 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini425 – 472PHD-typeInterPro annotationAdd BLAST48
Domaini504 – 551PHD-typeInterPro annotationAdd BLAST48
Domaini584 – 641ChromoInterPro annotationAdd BLAST58
Domaini677 – 712ChromoInterPro annotationAdd BLAST36
Domaini793 – 977Helicase ATP-bindingInterPro annotationAdd BLAST185
Domaini1109 – 1258Helicase C-terminalInterPro annotationAdd BLAST150

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1343 – 1363Sequence analysisAdd BLAST21
Coiled coili1710 – 1731Sequence analysisAdd BLAST22
Coiled coili1901 – 1921Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0383. Eukaryota.
COG0553. LUCA.
GeneTreeiENSGT00760000119067.

Family and domain databases

CDDicd00024. CHROMO. 2 hits.
cd00079. HELICc. 1 hit.
Gene3Di3.30.40.10. 2 hits.
InterProiView protein in InterPro
IPR012957. CHD_C2.
IPR012958. CHD_N.
IPR016197. Chromo-like_dom_sf.
IPR000953. Chromo/chromo_shadow_dom.
IPR023780. Chromo_domain.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR009462. DUF1086.
IPR009463. DUF1087.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000330. SNF2_N.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF08074. CHDCT2. 1 hit.
PF08073. CHDNT. 1 hit.
PF00385. Chromo. 1 hit.
PF06461. DUF1086. 1 hit.
PF06465. DUF1087. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00628. PHD. 2 hits.
PF00176. SNF2_N. 1 hit.
SMARTiView protein in SMART
SM00298. CHROMO. 2 hits.
SM00487. DEXDc. 1 hit.
SM01146. DUF1086. 1 hit.
SM01147. DUF1087. 1 hit.
SM00490. HELICc. 1 hit.
SM00249. PHD. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF54160. SSF54160. 3 hits.
SSF57903. SSF57903. 1 hit.
PROSITEiView protein in PROSITE
PS50013. CHROMO_2. 2 hits.
PS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 2 hits.

Sequencei

Sequence statusi: Complete.

G1QWK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGERRQGSGQ LPEVGLVWPG RPISGIYSSL FVCFCPGYQL PSVQSIAVLF
60 70 80 90 100
RGIWDKRWGI KSKASGLGPN LLLLIFSLPT TLCQIYVENE EDPEEDLSET
110 120 130 140 150
ETPKLKKKKK PKKPRDPKIP KSKRQKKERM LLCRQLGDSS GEGPEFVEEE
160 170 180 190 200
EEVALRSDSE GSDYTPGKKK KKKLGPKKEK KSKSKRKEEE EEDDDDDDSK
210 220 230 240 250
EPKSSAQLLE DWGMEDIDHV FSEEDYRTLT NYKAFSQFVR PLIAAKEFHQ
260 270 280 290 300
IAVSKMMMVL GAKWREFSTN NPFKGSSGAS VAAAAAAAVA VVESMVTATE
310 320 330 340 350
VAPPPPPVEV PIRKAKTKEG KGPNARRKPK GSPRVPDAKK PKPKKVAPLK
360 370 380 390 400
IKLGGFGSKR KRSSSEDDDL DVESDFDDAS INSYSVSDGS TSRSSRSRKK
410 420 430 440 450
LRTTKKKKKG EEEVTAVDGY ETDHQDYCEV CQQGGEIILC DTCPRAYHMV
460 470 480 490 500
CLDPDMEKAP EGKWSCPHCE KEGIQWEAKE DNSEGEEILE EVGGDLEEED
510 520 530 540 550
DHHMEFCRVC KDGGELLCCD TCPSSYHIHC LNPPLPEIPN GEWLCPRCTC
560 570 580 590 600
PALKGKVQKI LIWKWGQPPS PTPVPRPPDA DPNTPSPKPL EGRPERQFFV
610 620 630 640 650
KWQGMSYWHC SWVSELQLEL HCQVMFRNYQ RKNDMDEPPS GDFGGDEEKS
660 670 680 690 700
RKRKNKDPKF AEMEERFYRY GIKPEWMMIH RILNHSVDKK GHVHYLIKWR
710 720 730 740 750
DLPYDQASWE SEDVEIQDYD LFKQSYWNHR ELMRGEEGRP GKKLKKVKLR
760 770 780 790 800
KLERPPETPT VDPTVKYERQ PEYLDATGGT LHPYQMEGLN WLRFSWAQGT
810 820 830 840 850
DTILADEMGL GKTVQTAVFL YSLYKEGHSK GPFLVSAPLS TIINWEREFE
860 870 880 890 900
MWAPDMYVVT YVGDKDSRAI IRENEFSFED NAIRGGKKAS RMKKEASVKF
910 920 930 940 950
HVLLTSYELI TIDMAILGSI DWACLIVDEA HRLKNNQSKF FRVLNGYSLQ
960 970 980 990 1000
HKLLLTGTPL QNNLEELFHL LNFLTPERFH NLEGFLEEFA DIAKEDQIKK
1010 1020 1030 1040 1050
LHDMLGPHML RRLKADVFKN MPSKTELIVR VELSPMQKKY YKYILTRNFE
1060 1070 1080 1090 1100
ALNARGGGNQ VSLLNVVMDL KKCCNHPYLF PVAAMEAPKM PNGMYDGSAL
1110 1120 1130 1140 1150
IRASGKLLLL QKMLKNLKEG GHRVLIFSQM TKMLDLLEDF LEHEGYKYER
1160 1170 1180 1190 1200
IDGGITGNMR QEAIDRFNAP GAQQFCFLLS TRAGGLGINL ATADTVIIYD
1210 1220 1230 1240 1250
SDWNPHNDIQ AFSRAHRIGQ NKKVMIYRFV TRASVEERIT QVAKKKMMLT
1260 1270 1280 1290 1300
HLVVRPGLGS KTGSMSKQEL DDILKFGTEE LFKDEATDGG GDNKEGEDSS
1310 1320 1330 1340 1350
VIHYDDKAIE RLLDRNQDET EDTELQGMNE YLSSFKVAQY VVREEEMGEE
1360 1370 1380 1390 1400
EEVEREIIKQ EESVDPDYWE KLLRHHYEQQ QEDLARNLGK GKRIRKQVNY
1410 1420 1430 1440 1450
NDGSQEDRDW QDDQSDNQSD YSVASEEGDE DFDERSEAPR RPSRKGLRND
1460 1470 1480 1490 1500
KDKPLPPLLA RVGGNIEVLG FNARQRKAFL NAIMRYGMPP QDAFTTQWLV
1510 1520 1530 1540 1550
RDLRGKSEKE FKAYVSLFMR HLCEPGADGA ETFADGVPRE GLSRQHVLTR
1560 1570 1580 1590 1600
IGVMSLIRKK VQEFEHVNGR WSMELAEVEE NKKMSQPGSP SPKTPTPSTP
1610 1620 1630 1640 1650
GDTQPNTPAP VPPAEDGIKI EENSLKEEES IEGEKEVKSA APETAIECTQ
1660 1670 1680 1690 1700
APAPASEDEK VVVEPPEGEE KVEKAEVKER TEEPMETEPK GAADVEKVEE
1710 1720 1730 1740 1750
KSAIDLTPIV VEDKEEKKEE EEKKEVMLQN GETPKDLNDE KQKKNIKQRF
1760 1770 1780 1790 1800
MFNIADGGFT ELHSLWQNEE RAATVTKKTY EIWHRRHDYW LLAGIINHGY
1810 1820 1830 1840 1850
ARWQDIQNDP RYAILNEPFK GEMNRGNFLE IKNKFLARRF KLLEQALVIE
1860 1870 1880 1890 1900
EQLRRAAYLN MSEDPSHPSM ALNTRFAEVE CLAESHQHLS KESMAGNKPA
1910 1920 1930 1940 1950
NAVLHKVLKQ LEELLSDMKA DVTRLPATIA RIPPVAVRLQ MSERNILSRL
1960
ANRAPEPTPQ QVAQQQ
Length:1,966
Mass (Da):224,326
Last modified:May 1, 2013 - v2
Checksum:i2052D5B6AAADD823
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01078470 Genomic DNA. No translation available.
ADFV01078471 Genomic DNA. No translation available.
ADFV01078472 Genomic DNA. No translation available.
ADFV01078473 Genomic DNA. No translation available.
ADFV01078474 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSNLET00000005598; ENSNLEP00000005322; ENSNLEG00000004330.

Similar proteinsi

Entry informationi

Entry nameiG1QWK1_NOMLE
AccessioniPrimary (citable) accession number: G1QWK1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: May 1, 2013
Last modified: December 20, 2017
This is version 44 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported