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Protein
Submitted name:

Capping actin protein of muscle Z-line alpha subunit 1

Gene

CAPZA1

Organism
Myotis lucifugus (Little brown bat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin cappingSAAS annotation, Actin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Capping actin protein of muscle Z-line alpha subunit 1Imported
Gene namesi
Name:CAPZA1Imported
OrganismiMyotis lucifugus (Little brown bat)Imported
Taxonomic identifieri59463 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaChiropteraMicrochiropteraVespertilionidaeMyotis
Proteomesi
  • UP000001074 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Subunit structurei

Heterodimer of an alpha and a beta subunit.SAAS annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi59463.ENSMLUP00000008929.

Family & Domainsi

Sequence similaritiesi

Belongs to the F-actin-capping protein alpha subunit family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0836. Eukaryota.
ENOG410ZAWX. LUCA.
GeneTreeiENSGT00390000006476.
InParanoidiG1PEI5.
OMAiACDSALR.
OrthoDBiEOG091G0KST.
TreeFamiTF314822.

Family and domain databases

InterProiView protein in InterPro
IPR002189. CapZ_alpha.
IPR037282. CapZ_alpha/beta.
IPR017865. F-actin_cap_asu_CS.
PANTHERiPTHR10653. PTHR10653. 1 hit.
PfamiView protein in Pfam
PF01267. F-actin_cap_A. 1 hit.
PRINTSiPR00191. FACTINCAPA.
SUPFAMiSSF90096. SSF90096. 1 hit.
PROSITEiView protein in PROSITE
PS00748. F_ACTIN_CAPPING_A_1. 1 hit.
PS00749. F_ACTIN_CAPPING_A_2. 1 hit.

Sequencei

Sequence statusi: Complete.

G1PEI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADFEDRVSD EEKVRIAAKF ITHAPPGEFN EVFNDVRLLL SNDNLLREGA
60 70 80 90 100
AHAFAQYNMD QFTPVKIEGY EDQVLITEHG DLGNSRFLDP RNKISFKFDH
110 120 130 140 150
LRKEASDPQP EEVDGGLKSW RESCDSALRA YVKDHYSSGF CTVVYAKTID
160 170 180 190 200
GQQTIIACIE SHQFQPKNFW NGRWRSEWKF TITPPTAQVV GVLKIQVHYY
210 220 230 240 250
EDGNVQLVSH KDVQDSVTVS NEAQTAKEFI KIIEHAENEY QTAISENYQT
260 270 280
MSDTTFKALR RQLPVTRTKI DWNKILSYKI GKEMQNA
Length:287
Mass (Da):33,019
Last modified:October 19, 2011 - v1
Checksum:i29B9366CCB41776B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAPE02024709 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMLUT00000009794; ENSMLUP00000008929; ENSMLUG00000009796.

Similar proteinsi

Entry informationi

Entry nameiG1PEI5_MYOLU
AccessioniPrimary (citable) accession number: G1PEI5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 22, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported