G1NR93 (G1NR93_MELGA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

Name:

LOC100551140 Ensembl ENSMGAP00000016474

Organism

Meleagris gallopavo (Common turkey) [Reference proteome] Ensembl ENSMGAP00000016474

Taxonomic identifier

9103 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Meleagridinae › Meleagris

Protein attributes

Sequence length	912 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMGAP00000016474

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA recombination Inferred from electronic annotation. Source: Compara DNA ligation involved in DNA repair Inferred from electronic annotation. Source: Compara DNA replication Inferred from electronic annotation. Source: UniProtKB-KW T cell differentiation in thymus Inferred from electronic annotation. Source: Compara T cell receptor V(D)J recombination Inferred from electronic annotation. Source: Compara cell proliferation Inferred from electronic annotation. Source: Compara central nervous system development Inferred from electronic annotation. Source: Compara chromosome organization Inferred from electronic annotation. Source: Compara double-strand break repair via nonhomologous end joining Inferred from electronic annotation. Source: Compara immunoglobulin V(D)J recombination Inferred from electronic annotation. Source: Compara in utero embryonic development Inferred from electronic annotation. Source: Compara isotype switching Inferred from electronic annotation. Source: Compara negative regulation of neuron apoptotic process Inferred from electronic annotation. Source: Compara neuron apoptotic process Inferred from electronic annotation. Source: Compara nucleotide-excision repair, DNA gap filling Inferred from electronic annotation. Source: Compara positive regulation of fibroblast proliferation Inferred from electronic annotation. Source: Compara positive regulation of neurogenesis Inferred from electronic annotation. Source: Compara pro-B cell differentiation Inferred from electronic annotation. Source: Compara response to X-ray Inferred from electronic annotation. Source: Compara response to gamma radiation Inferred from electronic annotation. Source: Compara single strand break repair Inferred from electronic annotation. Source: Compara somatic stem cell maintenance Inferred from electronic annotation. Source: Compara
Cellular_component	DNA ligase IV complex Inferred from electronic annotation. Source: Compara DNA-dependent protein kinase-DNA ligase 4 complex Inferred from electronic annotation. Source: Compara condensed chromosome Inferred from electronic annotation. Source: Compara cytoplasm Inferred from electronic annotation. Source: Compara focal adhesion Inferred from electronic annotation. Source: Compara plasma membrane Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: Compara DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G1NR93 [UniParc]. Last modified October 19, 2011. Version 1. Checksum: 3C27F093A84A20D1	FASTA	912	104,286
	10 20 30 40 50 60 MASAPASQLS PKRTVASHVP FADLCSTLER IQKCKSRPEK TKYFKDFLDS WRKFHSALHQ 70 80 90 100 110 120 KEKDVTDSFY PAMRLILPQL ERERMAYGIK ETMLAKLYIE LLNLPKDGKD AVKLLNYRTP 130 140 150 160 170 180 TGSRGDAGDF AMIAYFVLKP RSPKRGRLTV EQVNELLDAI ANNNAAKNKG LVKKSLLQLI 190 200 210 220 230 240 TQSTALEQKW LIRMIIKDLK LGVSQQTIFS IFHPDAAELH NVTTDLEKVC RQLHDPSVSL 250 260 270 280 290 300 SDVSIMLFSA FKPMLAAIAD VQQIEKQMNN QVFYIETKLD GERMQMHKDG DVYKYFSRNG 310 320 330 340 350 360 FDYTQQFGAS PLDGSLTPFI HNVFKNDIQN CILDGEMMAY NPETQTFMQK GNKFDIKRMV 370 380 390 400 410 420 EDSDLQTCFC VFDVLMINDQ KLGHESLSKR YKILNNVFTP VTGRIHVVHK KSARTRKEVI 430 440 450 460 470 480 DALNEAIDNR EEGIMIKDPM STYKPDKRGE GWLKIKPEYV NGLMDELDLL IVGGYWGKGS 490 500 510 520 530 540 RGGMMSHFLC AIAETPAPNE KPTAFHSICR VGSGYTMKEL YDLGLKLAKH WKPYNRKDPP 550 560 570 580 590 600 CNILCGTEKP EMYIEPCNSV IVQIKAAEIV DSDMYKTDCT LRFPRIEKIR EDKEWYECMT 610 620 630 640 650 660 LDMLEHLRSR AEGKLASKHL YIDEYDEPQE KKRRTVPKVK KVIGIAEQFK APDLSNVNKV 670 680 690 700 710 720 SSVFEDVEFC VMTGTGRYSK SELESKIAEC GGSVVQNPGP DTYCVIVGAE NVRVKNIIAS 730 740 750 760 770 780 NKYDVVKAEW LLQCFQSKML VPWQPAFMIH MSPDTKEHFA REYDCYGDSY TADTDVAQLK 790 800 810 820 830 840 EVFSRVKDNK RMPLDLIAEL EERYSWNSCQ LCIFRGNTIY VDYYATINKP STKIHGTRLS 850 860 870 880 890 900 VRALELRFYG AKVVPLLEEG VSHVVIGEDH SRVKEVKALR RMFGKKFKIV SELWVTVSIK 910 EGAPKNENQF LI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis." Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A., Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K., Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C., Frederickson K.M. , Flicek P., Florea L., Folkerts O., Groenen M.A., Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P., Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T., Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M., Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D., Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C., Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J., Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P., Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X., Zhang Y., Reed K.M. PLoS Biol. 8:E1000475-E1000475(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (SEP-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
RefSeq	XP_003203267.1. XM_003203219.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMGAT00000017448; ENSMGAP00000016474; ENSMGAG00000015532.
GeneID	100551140.
KEGG	mgp:100551140.
Phylogenomic databases
GeneTree	ENSGT00700000104500.
KO	K10777.
OMA	HMCPSTK.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit.
InterPro	IPR001357. BRCT_dom. IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR021536. DNA_ligase_IV. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF00533. BRCT. 1 hit. PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. PF11411. DNA_ligase_IV. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 2 hits. [Graphical view]
SUPFAM	SSF52113. BRCT. 2 hits. SSF50249. Nucleic_acid_OB. 1 hit. SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS50172. BRCT. 2 hits. PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G1NR93_MELGA

Accession

Primary (citable) accession number: G1NR93

Entry history

Integrated into UniProtKB/TrEMBL:	October 19, 2011
Last sequence update:	October 19, 2011
Last modified:	April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)