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G1MFD2

- G1MFD2_AILME

UniProt

G1MFD2 - G1MFD2_AILME

Protein
Submitted name:

Uncharacterized protein

Gene

HK2

Organism
Ailuropoda melanoleuca (Giant panda)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. hexokinase activity Source: Ensembl

    GO - Biological processi

    1. apoptotic mitochondrial changes Source: Ensembl
    2. glucose metabolic process Source: Ensembl
    3. glycolytic process Source: UniProtKB-KW
    4. regulation of glucose import Source: Ensembl

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotation, Transferase

    Keywords - Biological processi

    GlycolysisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:HK2Imported
    OrganismiAiluropoda melanoleuca (Giant panda)Imported
    Taxonomic identifieri9646 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeAiluropoda
    ProteomesiUP000008912: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial outer membrane Source: Ensembl

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the hexokinase family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00390000017159.
    KOiK00844.
    OMAiHHLGLES.
    OrthoDBiEOG7S21X5.
    TreeFamiTF314238.

    Family and domain databases

    InterProiIPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view]
    PANTHERiPTHR19443. PTHR19443. 1 hit.
    PfamiPF00349. Hexokinase_1. 2 hits.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view]
    PRINTSiPR00475. HEXOKINASE.
    PROSITEiPS00378. HEXOKINASES. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G1MFD2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIASHLLAYF FTELNHDQVQ KVDQYLYHMR LSDENLLEIS KRFRKEMEKG    50
    LGATTHPTAS VKMLPTFVRS TPDGTEHGEF LALDLGGTNF RVLRVRVTDN 100
    GLQKVEMENQ IYAIPEDLMR GSGTQLFDHI AECLANFMDK LQIKDKKLPL 150
    GFTFSFPCVQ TKLDESFLVS WTKGFKSSGV EGKDVVTLIR KAIQRRGDFD 200
    IDIVAVVNDT VGTMMTCGYD DQNCEIGLIV GTGSNACYME EMRHIDMVEG 250
    DEGRMCINME WGAFGDDGTL DDFRTEFDQE IDMGSLNPGK QLFEKMISGM 300
    YMGELVRLIL VKMAKEELLF GGKVSPGLLT TGQFETKDVS DIEGEKDGTR 350
    KAREVLLRLG MDPTQEDCVA THRICQIVST RSASLCAATL AAVLRRIKEN 400
    KGEERLRSTI GVDGSVYKKH PHFAKRLHKA VRRLVPDCDV RFLRSEDGSG 450
    KGAAMVTAVA YRLADQHRAR QNTLESLKLS REQLLEVKRR MNVEMERGLS 500
    KETHAIAPVK MLPTYVCATP DGTEKGDFLA LDLGGTNFRV LLVRVRNGKR 550
    RGVEMHNKIY SIPQEVMHGT GDELFDHIVQ CIADFLEYMG MKGVSLPLGF 600
    TFSFPCQQNS LDESILLKWT KGFKASGCEG EDVVMLLKEA IHRREEFDLD 650
    VVAVVNDTVG TMMTCGYEDP HCEVGLIVGT GSNACYMEEM RNVELVEGEE 700
    GRMCVNMEWG AFGDNGCLDD FRTEFDVAVD ELSLNPGRQR FEKMISGMYL 750
    GEIVRNILID FTKRGLLFRG RISERLKTRG IFETKFLSQI ESDCLALLQV 800
    RAILRHLGLE STCDDSIIVK EVCTVVARRA AQLCGAGMAA VVDKIRENRG 850
    LDTLKVTVGV DGTLYKLHPH FAKVMHETVK DLAPKCDVSF LESEDGSGKG 900
    AALITAVACR IREAGQR 917
    Length:917
    Mass (Da):102,485
    Last modified:October 19, 2011 - v1
    Checksum:iDA0431CD20CE5F49
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ACTA01035702 Genomic DNA. No translation available.
    ACTA01043701 Genomic DNA. No translation available.
    ACTA01051701 Genomic DNA. No translation available.
    RefSeqiXP_002921507.1. XM_002921461.1.

    Genome annotation databases

    EnsembliENSAMET00000018793; ENSAMEP00000018062; ENSAMEG00000017077.
    GeneIDi100470774.
    KEGGiaml:100470774.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ACTA01035702 Genomic DNA. No translation available.
    ACTA01043701 Genomic DNA. No translation available.
    ACTA01051701 Genomic DNA. No translation available.
    RefSeqi XP_002921507.1. XM_002921461.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSAMET00000018793 ; ENSAMEP00000018062 ; ENSAMEG00000017077 .
    GeneIDi 100470774.
    KEGGi aml:100470774.

    Phylogenomic databases

    GeneTreei ENSGT00390000017159.
    KOi K00844.
    OMAi HHLGLES.
    OrthoDBi EOG7S21X5.
    TreeFami TF314238.

    Family and domain databases

    InterProi IPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view ]
    PANTHERi PTHR19443. PTHR19443. 1 hit.
    Pfami PF00349. Hexokinase_1. 2 hits.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view ]
    PRINTSi PR00475. HEXOKINASE.
    PROSITEi PS00378. HEXOKINASES. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence and de novo assembly of the giant panda genome."
      Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.
      , Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L., Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J., Wang J.
      Nature 463:311-317(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiG1MFD2_AILME
    AccessioniPrimary (citable) accession number: G1MFD2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3