POU1F1

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
DNA bindingⁱ	254 – 313	HomeoboxPROSITE-ProRule annotationAdd BLAST		60

GO - Molecular functionⁱ

RNA polymerase II activating transcription factor binding Source: Ensembl
RNA polymerase II transcription coactivator activity Source: Ensembl
RNA polymerase II transcription factor activity, sequence-specific DNA binding Source: Ensembl
sequence-specific DNA binding Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological process	Transcription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: POU domain proteinUniRule annotation
Gene namesⁱ	Name:POU1F1Imported
Organismⁱ	Ailuropoda melanoleuca (Giant panda)Imported
Taxonomic identifierⁱ	9646 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Laurasiatheria › Carnivora › Caniformia › Ursidae › Ailuropoda
Proteomesⁱ	UP000008912 Componentⁱ: Unassembled WGS sequence

Keywords - Cellular componentⁱ

NucleusPROSITE-ProRule annotationSAAS annotation

Interactionⁱ

GO - Molecular functionⁱ

RNA polymerase II activating transcription factor binding Source: Ensembl

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	9646.ENSAMEP00000007676

STRINGⁱ

9646.ENSAMEP00000007676

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	164 – 238	POU-specificInterPro annotationAdd BLAST		75
Domainⁱ	252 – 312	HomeoboxInterPro annotationAdd BLAST		61

Sequence similaritiesⁱ

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domainⁱ

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG3802 Eukaryota ENOG410XQ7X LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118935
InParanoidⁱ	G1LL54
OMAⁱ	MSCQPFT
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0U0S
TreeFamⁱ	TF316413

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00086 homeodomain, 1 hit
InterProⁱ	View protein in InterPro IPR009057 Homeobox-like_sf IPR017970 Homeobox_CS IPR001356 Homeobox_dom IPR010982 Lambda_DNA-bd_dom_sf IPR015586 Pit_1 IPR013847 POU IPR000327 POU_dom
PANTHERⁱ	PTHR11636:SF84 PTHR11636:SF84, 2 hits
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00046 Homeobox, 1 hit PF00157 Pou, 1 hit
PRINTSⁱ	PR00028 POUDOMAIN
SMARTⁱ	View protein in SMART SM00389 HOX, 1 hit SM00352 POU, 1 hit
SUPFAMⁱ	SSF46689 SSF46689, 1 hit SSF47413 SSF47413, 1 hit
PROSITEⁱ	View protein in PROSITE PS00027 HOMEOBOX_1, 1 hit PS50071 HOMEOBOX_2, 1 hit PS00035 POU_1, 1 hit PS00465 POU_2, 1 hit PS51179 POU_3, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

G1LL54-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
GEQQFSSVFY CLVGMSCQPF TSADTFIPLN SEASATLPLI MHHSAAECLP 
        60         70         80         90        100
VSNHATNVMS TVPSILSLIQ TPKCLRAYFS VPTLGNTATG LHYSVPSCHY 
       110        120        130        140        150
GNQPSTYGVM AGSLTPCLYK FPDHTLSHGF PPMHQPLLAE DPTVTDFKQE 
       160        170        180        190        200
LRRKSKLVEE PIDMDSPEIR ELEKFANEFK VRRIKLGYTQ TNVGEALAAV 
       210        220        230        240        250
HGSEFSQTTI CRFENLQLSF KNACKLKAIL SKWLEEAEQV GALYNEKVGV 
       260        270        280        290        300
NERKRKRRTT ISIAAKDALE RHFGEQNKPS SQEIMRMAEE LNLEKEVVRV 
       310        320        330 
WFCNRRQREK RVKTSLNQSL FTISKEHLEC R

Length:331

Mass (Da):37,418

Last modified:October 19, 2011 - v1

Checksum:ⁱ19EA346A9FAACDBC

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	ACTA01186731 Genomic DNA No translation available. ACTA01194729 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

ACTA01186731 Genomic DNA No translation available.
ACTA01194729 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENSAMET00000007997; ENSAMEP00000007676; ENSAMEG00000007286

Ensemblⁱ

ENSAMET00000007997; ENSAMEP00000007676; ENSAMEG00000007286

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
G1LL54	D2HHQ5	Ailuropoda melanoleuca (Giant panda)	331	UniRef100_G1LL54	Cluster: POU domain protein	2

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
G1LL54	P28069-2 A0A2J8QLC5 H2QMY4 G3TH87 H0WQ72 UPI0001512F73 D2HHQ5 W5Q6G9 UPI0005FBC485 D3JXK1 +89	Pan troglodytes (Chimpanzee) Loxodonta africana (African elephant) Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby) Ailuropoda melanoleuca (Giant panda) Ovis aries (Sheep) Capra hircus (Goat) Echinops telfairi (Lesser hedgehog tenrec) Rattus norvegicus (Rat) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti) And more	317	UniRef90_P28069-2	Cluster: Isoform A of Pituitary-specific positive transcription factor 1	100

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
G1LL54	P28069-2 A0A2J8QLC5 H2QMY4 G3TH87 D2HHQ5 H0WQ72 UPI0001512F73 W5Q6G9 UPI0005FBC485 D3JXK1 +329	Pan troglodytes (Chimpanzee) Loxodonta africana (African elephant) Ailuropoda melanoleuca (Giant panda) Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby) Ovis aries (Sheep) Capra hircus (Goat) Echinops telfairi (Lesser hedgehog tenrec) Pteropus vampyrus (Large flying fox) Pan paniscus (Pygmy chimpanzee) (Bonobo) Mus musculus (Mouse) And more	317	UniRef50_P28069-2	Cluster: Isoform A of Pituitary-specific positive transcription factor 1	340

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	ACTA01186731 Genomic DNA No translation available. ACTA01194729 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

ACTA01186731 Genomic DNA No translation available.
ACTA01194729 Genomic DNA No translation available.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9646.ENSAMEP00000007676

STRINGⁱ

9646.ENSAMEP00000007676

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSAMET00000007997; ENSAMEP00000007676; ENSAMEG00000007286

Ensemblⁱ

ENSAMET00000007997; ENSAMEP00000007676; ENSAMEG00000007286

Phylogenomic databases

eggNOGⁱ	KOG3802 Eukaryota ENOG410XQ7X LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118935
InParanoidⁱ	G1LL54
OMAⁱ	MSCQPFT
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0U0S
TreeFamⁱ	TF316413

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00086 homeodomain, 1 hit
InterProⁱ	View protein in InterPro IPR009057 Homeobox-like_sf IPR017970 Homeobox_CS IPR001356 Homeobox_dom IPR010982 Lambda_DNA-bd_dom_sf IPR015586 Pit_1 IPR013847 POU IPR000327 POU_dom
PANTHERⁱ	PTHR11636:SF84 PTHR11636:SF84, 2 hits
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00046 Homeobox, 1 hit PF00157 Pou, 1 hit
PRINTSⁱ	PR00028 POUDOMAIN
SMARTⁱ	View protein in SMART SM00389 HOX, 1 hit SM00352 POU, 1 hit
SUPFAMⁱ	SSF46689 SSF46689, 1 hit SSF47413 SSF47413, 1 hit
PROSITEⁱ	View protein in PROSITE PS00027 HOMEOBOX_1, 1 hit PS50071 HOMEOBOX_2, 1 hit PS00035 POU_1, 1 hit PS00465 POU_2, 1 hit PS51179 POU_3, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	G1LL54_AILME
Accessionⁱ	G1LL54Primary (citable) accession number: G1LL54
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 19, 2011
	Last sequence update:	October 19, 2011
	Last modified:	March 28, 2018
	This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - G1LL54 (G1LL54_AILME)

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POU domain protein

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Functionⁱ

Regions

GO - Molecular functionⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Nucleus

Nucleus

Keywords - Cellular componentⁱ

Interactionⁱ

GO - Molecular functionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - G1LL54 (G1LL54_AILME)

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POU domain protein

POU1F1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ