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Protein
Submitted name:

Ryanodine receptor 2

Gene

RYR2

Organism
Ailuropoda melanoleuca (Giant panda)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Ryanodine receptor 2Imported
Gene namesi
Name:RYR2Imported
OrganismiAiluropoda melanoleuca (Giant panda)Imported
Taxonomic identifieri9646 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeAiluropoda
Proteomesi
  • UP000008912 Componenti: Unassembled WGS sequence

Subcellular locationi

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 66MIRInterPro annotationAdd BLAST56
Domaini73 – 118MIRInterPro annotationAdd BLAST46
Domaini126 – 181MIRInterPro annotationAdd BLAST56
Domaini187 – 244MIRInterPro annotationAdd BLAST58
Domaini252 – 309MIRInterPro annotationAdd BLAST58
Domaini500 – 710B30.2/SPRYInterPro annotationAdd BLAST211
Domaini926 – 1123B30.2/SPRYInterPro annotationAdd BLAST198
Domaini1238 – 1463B30.2/SPRYInterPro annotationAdd BLAST226

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG2243. Eukaryota.
ENOG410YCNW. LUCA.
GeneTreeiENSGT00760000119152.

Family and domain databases

CDDicd12877. SPRY1_RyR. 1 hit.
cd12878. SPRY2_RyR. 1 hit.
cd12879. SPRY3_RyR. 1 hit.
Gene3Di1.25.10.30. 2 hits.
InterProiView protein in InterPro
IPR001870. B30.2/SPRY.
IPR013320. ConA-like_dom_sf.
IPR014821. Ins145_P3_rcpt.
IPR035910. IP3R_RIH_dom_sf.
IPR036300. MIR_dom_sf.
IPR016093. MIR_motif.
IPR000699. RIH_dom.
IPR013333. Ryan_recept.
IPR003032. Ryanodine_rcpt.
IPR015925. Ryanodine_recept-rel.
IPR035761. SPRY1_RyR.
IPR035764. SPRY2_RyR.
IPR035762. SPRY3_RyR.
IPR003877. SPRY_dom.
PANTHERiPTHR13715. PTHR13715. 1 hit.
PfamiView protein in Pfam
PF08709. Ins145_P3_rec. 1 hit.
PF02815. MIR. 1 hit.
PF01365. RYDR_ITPR. 2 hits.
PF02026. RyR. 4 hits.
PF00622. SPRY. 3 hits.
PRINTSiPR00795. RYANODINER.
SMARTiView protein in SMART
SM00472. MIR. 4 hits.
SM00449. SPRY. 3 hits.
SUPFAMiSSF100909. SSF100909. 2 hits.
SSF49899. SSF49899. 3 hits.
SSF82109. SSF82109. 2 hits.
PROSITEiView protein in PROSITE
PS50188. B302_SPRY. 3 hits.
PS50919. MIR. 5 hits.

Sequencei

Sequence statusi: Complete.

G1L869-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
FFPQTAQGGG HRTLLYGHAI LLRHSYSGMY LCCLSTSRSS TDKLAFDVGL
60 70 80 90 100
QEDTTGEACW WTIHPASKQR SEGEKVRVGD DLILVSVSSE RYLHLSYGNG
110 120 130 140 150
SLHVDAAFQQ TLWSVAPISS GSEAAQGYLI GGDVLRLLHG HMDECLTVPS
160 170 180 190 200
GEHGEEQRRT VHYEGGAVSV HARSLWRLET LRVAWSGSHI RWGQPFRLRH
210 220 230 240 250
VTTGKYLSLM EDKSLLLMDK EKADVKSTAF TFRSSKEKLD VGVRKEVDGM
260 270 280 290 300
GTSEIKYGDS VCYIQHINTG LWLTYQSVDV KSVRMGSIQR KAIMHHEGHM
310 320 330 340 350
DDGLNLSRSQ HEESRTARVI RSTVFLFNRF IRGLDALSKK VKASTVDLPI
360 370 380 390 400
ESVSLSLQDL IGYFHPPDEH LEHEDKQNRL RALKNRQNLF QEEGMINLVL
410 420 430 440 450
ECIDRLHVYS SAAHFADVAG REAGESWKSI LNSLYELLAA LIRGNRKNCA
460 470 480 490 500
QFSGSLDWLI SRLERLEASS GILEVLHCVL VESPEALNII KEGHIKSIIS
510 520 530 540 550
LLDKHGRNHK VLDVLCSLCV CHGVAVRSNQ HLICDNLLPG RDLLLQTRLV
560 570 580 590 600
NHVSSMRPNI FLGVSEGSAQ YKKWYYELMV DHTEPFVTAE ATHLRVGWAS
610 620 630 640 650
TEGYSPYPGG GEEWGGNGVG DDLFSYGFDG LHLWSGCIAR TVSSPNQHLL
660 670 680 690 700
RTDDVISCCL DLSAPSISFR INGQPVQGMF ENFNIDGLFF PVVSFSAGIK
710 720 730 740 750
VRFLLGGRHG EFKFLPPPGY APCYEAVLPK EKLKVEHSRE YKQERTYTRD
760 770 780 790 800
LLGPTVSLTQ AAFTPIPVDT SQIVLPPHLE RIREKLAENI HELWVMNKIE
810 820 830 840 850
LGWQYGPVRD DNKRQHPCLV EFSKLPEQER NYNLQMSLET LKTLLALGCH
860 870 880 890 900
VGISDEHAEE KVKKMKLPKN YQLTSGYKPA PMDLSFIKLT PSQEAMVDKL
910 920 930 940 950
AENAHNVWAR DRIRQGWTYG IQQDVKNRRN PRLVPYALLD DRTKKSNKDS
960 970 980 990 1000
LREAVRTLLG YGYNLEAPDQ DPGARAEVCS GTGERFRIFR AEKTYAVKAG
1010 1020 1030 1040 1050
RWYFEFEAVT AGDMRVGWSR PGCQPDQELG SDERAFAFDG FKAQRWHQGN
1060 1070 1080 1090 1100
EHYGRSWQAG DVVGCMVDMT EHTMLFTLNG EILLDDSGSE LAFKDFDVGD
1110 1120 1130 1140 1150
GFIPVCSLGV AQVGRMNFGK DVSTLKYFTI CGLQEGYEPF AVNTNRDITM
1160 1170 1180 1190 1200
WLSKRLPQFL QVPSNHEHIE VTRIDGTIDS SPCLKVTQKS FGSQNSSTDI
1210 1220 1230 1240 1250
MFYRLSMPIE CAEVFSKTVA GGLPGAGLFG PKNDLEDYDA DSDFEVLMKT
1260 1270 1280 1290 1300
AHGHLVPDRV DKDKEATKPE FNNHKDYAQE KPSRLKQRFL LRRTKPDYST
1310 1320 1330 1340 1350
SHSARLTEDV LADDRDDYDY LMQTSTYYYS VRIFPGQEPA NVWVGWITSD
1360 1370 1380 1390 1400
FHQYDTGFDL DRVRTVTVTL GDEKGKVHES IKRSNCYMVC AGESMSPGQG
1410 1420 1430 1440 1450
RNNNGLEIGC VVDAASGLLT FTANGKELGT YYQVEPSTKL FPAVFAQATS
1460 1470 1480 1490 1500
PNVFQFELGR IKNVMPLSAG LFKSEHKNPV PQCPPRLHVQ FLSHVLWSRM
1510 1520 1530 1540 1550
PNQFLKVDVS RISERQGWLV QCLDPLQFMS LHIPEENRSV DILELTEQEE
1560 1570 1580 1590 1600
LLKFHYHTLR LYSAVCALGN HRVAHALCSH VDEPQLLYAI ENKYMPGLLR
1610 1620 1630 1640 1650
AGYYDLLIDI HLSSYATARL MMNSEFIVPM TEETKSITLF PDENKKHGLP
1660 1670 1680 1690 1700
GIGLSTSLRP RIQFSSPSFV SINNECYQYS PEFPLDILKA KTIQMLTEAV
1710 1720 1730 1740 1750
KEGSLHARDP VGGTTEFLFV PLIKLFYTLL IMGIFHNEDL KHILRLIEPS
1760 1770 1780 1790 1800
VFKEAATPDE ETDVLEKEPS PEDARPEGAG EEEAKGGKRP KEGLLQMKLP
1810 1820 1830 1840 1850
EPVKLQMCLL LQYLCDCQVR HRIEAIVAFS DDFVAKLQDN QRFRYNEVMQ
1860 1870 1880 1890 1900
ALNMSAALTA RKTKEFRSPP QEQINMLLNF KDDKSECPCP EEIRDQLLDF
1910 1920 1930 1940 1950
HEDLMTHCGI ELDEDGSLDG NSDLTIRGRL LSLVEKVTYL KKKQAEKPVE
1960 1970 1980 1990 2000
SDSKKSSTLQ QLISETMVRW AQESVIEDPE LVRAMFVLLH RQYDGIGGLV
2010 2020 2030 2040 2050
RALPKTYTIN GVSVEDTINL LASLGQIRSL LSVRMGKEEE KLMIRGLGDI
2060 2070 2080 2090 2100
MNNKVFYQHP NLMRALGMHE TVMEVMVNVL GGGESKEITF PKMVANCCRF
2110 2120 2130 2140 2150
LCYFCRISRQ NQKAMFDHLS YLLENSSVGL ASPAMRGSTP LDVAAASVMD
2160 2170 2180 2190 2200
NNELALALRE PDLEKVVRYL AGCGLQSCQM LVSKGYPDIG WNPVEGERYL
2210 2220 2230 2240 2250
DFLRFAVFCN GESVEENANV VVRLLIRRPE CFGPALRGEG GNGLLAAMEE
2260 2270 2280 2290 2300
AIKIAEDPSR DGPSPTSGSS KTLDTEEEED DTIHMGNAIM TFYAALIDLL
2310 2320 2330 2340 2350
GRCAPEMHLI HAGKGEAIRI RSILRSLIPL GDLVGVISIG FQMPTIAKDG
2360 2370 2380 2390 2400
NVVEPDMSAG FCPDHKAAMV LFLDRVYGIE VQDFLLHLLE VGFLPDLRAA
2410 2420 2430 2440 2450
ASLDTAALSA TDMALALNRY LCTAVLPLLT RCAPLFAGTE HHASLIDSLL
2460 2470 2480 2490 2500
HTVYRLSKGC SLTKAQRDAI EICLLSICGQ LRPSMMQHLL RRLVFDVPLL
2510 2520 2530 2540 2550
NEHAKMPLKL LTNHYERCWK YYCLPGGWGN FGAASEEELH LSRKLFWGIF
2560 2570 2580 2590 2600
DALSQKKYEQ ELFKLALPCL SAVAGALPPD YMESNYVSMM EKQSSMDSEG
2610 2620 2630 2640 2650
NFNPQPVDTS NITIPEKLEY FINKYAEHSH DKWSMDKLAN GWIYGEIYSD
2660 2670 2680 2690 2700
SSKVQPLMKP YKLLSEKEKE IYRWPIKESL KTMLAWGWRI ERTREGDSMA
2710 2720 2730 2740 2750
LYNRTRRISQ TSQVSVDAAH GYSPRAIDMS NVTLSRDLHA MAEMMAENYH
2760 2770 2780 2790 2800
NIWAKKKKME LESKGGGNHP LLVPYDTLTA KEKAKDREKA QDILKFLQIN
2810 2820 2830 2840 2850
GYAVSSFRGF KDLELDTPSI EKRFAYSFLQ QLIRYVDEAH QYILEFDGGS
2860 2870 2880 2890 2900
RSKGEHFPYE QEIKFFAKVV LPLIDQYFKN HRLYFLSAAS RPLCSGGHAS
2910 2920 2930 2940 2950
NKEKEMVTSL FCKLGVLVRH RISLFGNDAT SIVNCLHILG QTLDARTVMK
2960 2970 2980 2990 3000
TGLESVKSAL RAFLDNAAED LEKTMENLKQ GQFTHTRNQP RGVTQIINYT
3010 3020 3030 3040 3050
TVALLPMLSS LFEHIGQHQF GEDLILEDVQ VSCYRILTSL YALGTSKSIY
3060 3070 3080 3090 3100
VERQRSALGE CLAAFAGAFP VAFLETHLDK HNVYSIYNTK SSRERAALNL
3110 3120 3130 3140 3150
PTNVEDVCPN IPSLEKLMEE IVELAESGIR YTQMPHVMEV ILPMLCSYMS
3160 3170 3180 3190 3200
RWWEHGPENN PERAEMCCTA LSSEHMNTLL GNILKIIYNN LGIDEGAWMK
3210 3220 3230 3240 3250
RLAVFSQPII NKVKPQLLKT HFLPLMEKLK KKAAMVVSEE DHLKAEARGD
3260 3270 3280 3290 3300
MSEAELLILD EFTTLARDLY AFYPLLIRFV DYNRAKWLKE PNPEAEDLFR
3310 3320 3330 3340 3350
MVAEVFIYWS KSHNFKREEQ NFVVQNEINN MSFLITDTKS KMSKAAVSDQ
3360 3370 3380 3390 3400
ERKKMKRRGD RYSMQTSLIV AALKRLLPIG LNICAPGDQE LIALAKNRFS
3410 3420 3430 3440 3450
MKDTEDEVRD IIRSNIHLQG KLEDPAIRWQ MALYKDLPNR TEDTSDPEKT
3460 3470 3480 3490 3500
VERVLDIANV LFHLEQKSTC MRRRYYSLVE HPQRSKKAVW HKLLSKQRKR
3510 3520 3530 3540 3550
AVVACFRMAP LYNLPRHRAV NLFLQGYEKS WIETEEHYFE DKLIEDLAKP
3560 3570 3580 3590 3600
GANPPEEEEG TKRVDPLHQL ILLFSRTALT EKCKLEEDFL YMAYADIMAK
3610
SCHDEEDDDG EEEVKSFE
Length:3,618
Mass (Da):409,630
Last modified:October 19, 2011 - v1
Checksum:iF836C9C64195B3B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACTA01002487 Genomic DNA. No translation available.
ACTA01010487 Genomic DNA. No translation available.
ACTA01018487 Genomic DNA. No translation available.
ACTA01026487 Genomic DNA. No translation available.
ACTA01034487 Genomic DNA. No translation available.
ACTA01042486 Genomic DNA. No translation available.
ACTA01170480 Genomic DNA. No translation available.
ACTA01178478 Genomic DNA. No translation available.
ACTA01186476 Genomic DNA. No translation available.
ACTA01194474 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSAMET00000003212; ENSAMEP00000003085; ENSAMEG00000002582.

Similar proteinsi

Entry informationi

Entry nameiG1L869_AILME
AccessioniPrimary (citable) accession number: G1L869
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 22, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported