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Protein
Submitted name:

Enhancer of zeste 2 polycomb repressive complex 2 subunit

Gene

EZH2

Organism
Ailuropoda melanoleuca (Giant panda)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Enhancer of zeste 2 polycomb repressive complex 2 subunitImported
Gene namesi
Name:EZH2Imported
OrganismiAiluropoda melanoleuca (Giant panda)Imported
Taxonomic identifieri9646 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeAiluropoda
Proteomesi
  • UP000008912 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi9646.ENSAMEP00000003001

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini508 – 610CXCInterPro annotationAdd BLAST103
Domaini617 – 732SETInterPro annotationAdd BLAST116

Phylogenomic databases

eggNOGiKOG1079 Eukaryota
COG2940 LUCA
GeneTreeiENSGT00780000121845
InParanoidiG1L7Y5
OMAiIKEAWIK
OrthoDBiEOG091G09L0
TreeFamiTF314509

Family and domain databases

CDDicd00167 SANT, 1 hit
InterProiView protein in InterPro
IPR026489 CXC_dom
IPR021654 EZH1/EZH2
IPR001005 SANT/Myb
IPR001214 SET_dom
IPR033467 Tesmin/TSO1-like_CXC
PfamiView protein in Pfam
PF11616 EZH2_WD-Binding, 1 hit
PF00856 SET, 1 hit
SMARTiView protein in SMART
SM01114 CXC, 1 hit
SM00717 SANT, 2 hits
SM00317 SET, 1 hit
PROSITEiView protein in PROSITE
PS51633 CXC, 1 hit
PS50280 SET, 1 hit

Sequencei

Sequence statusi: Complete.

G1L7Y5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKS MFSSNRQKIL
60 70 80 90 100
ERTEILNQEW KQRRIQPVHI LTSVSSLRGT RECSVTSDLD FPTQVIPLKT
110 120 130 140 150
LNAVASVPIM YSWSPLQQNF MVEDETVLHN IPYMGDEVLD QDGTFIEELI
160 170 180 190 200
KNYDGKVHGD RECGFINDEI FVELVNALGQ YNDDDDDDDG DDPDEREEKQ
210 220 230 240 250
KDLEENRDDK ESRPPRKFPS DKIFEAISSM FPDKGTAEEL KEKYKELTEQ
260 270 280 290 300
QLPGALPPEC TPNIDGPNAK SVQREQSLHS FHTLFCRRCF KYDCFLHRKC
310 320 330 340 350
NYSFHATPNT YKRKNTETAL DNKPCGPQCY QHLEGAKEFA AALTAERIKT
360 370 380 390 400
PPKRPGGRRR GRLPNNSSRP STPTINVLES KDTDSDREAG TETGGENNDK
410 420 430 440 450
EEEEKKDETS SSSEANSRCQ TPIKMKPNIE PPENVEWSGA EASMFRVLIG
460 470 480 490 500
TYYDNFCAIA RLIGTKTCRQ VYEFRVKESS IIAPAPAEDV DTPPRKKKRK
510 520 530 540 550
HRLWAAHCRK IQLKKDGSSN HVYNYQPCDH PRQPCDSSCP CVIAQNFCEK
560 570 580 590 600
FCQCSSECQN RFPGCRCKAQ CNTKQCPCYL AVRECDPDLC LTCGAADHWD
610 620 630 640 650
SKNVSCKNCS IQRGSKKHLL LAPSDVAGWG IFIKDPVQKN EFISEYCGEI
660 670 680 690 700
ISQDEADRRG KVYDKYMCSF LFNLNNDFVV DATRKGNKIR FANHSVNPNC
710 720 730 740 750
YAKVMMVNGD HRIGIFAKRA IQTGEELFFD YRYSQADALK YVGIEREMEI

P
Length:751
Mass (Da):85,995
Last modified:October 19, 2011 - v1
Checksum:i956B9F59D4088AED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACTA01090061 Genomic DNA No translation available.
ACTA01098061 Genomic DNA No translation available.
ACTA01106061 Genomic DNA No translation available.
RefSeqiXP_019659943.1, XM_019804384.1

Genome annotation databases

EnsembliENSAMET00000003127; ENSAMEP00000003001; ENSAMEG00000002791
GeneIDi100466177

Similar proteinsi

Entry informationi

Entry nameiG1L7Y5_AILME
AccessioniPrimary (citable) accession number: G1L7Y5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: March 28, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported