G1L7Y5 (G1L7Y5_AILME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSAMEP00000003001

Gene names

Name:

EZH2 Ensembl ENSAMEP00000003001

Organism

Ailuropoda melanoleuca (Giant panda) [Reference proteome] Ensembl ENSAMEP00000003001

Taxonomic identifier

9646 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Carnivora › Caniformia › Ursidae › Ailuropoda

Protein attributes

Sequence length	751 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 1 SET domain. RuleBase RU004538 SAAS SAAS001214
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSAMEP00000003001

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	G1 to G0 transition Inferred from electronic annotation. Source: Compara S phase of mitotic cell cycle Inferred from electronic annotation. Source: Compara cerebellar cortex development Inferred from electronic annotation. Source: Compara histone H3-K27 methylation Inferred from electronic annotation. Source: Compara negative regulation of epidermal cell differentiation Inferred from electronic annotation. Source: Compara negative regulation of retinoic acid receptor signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of striated muscle cell differentiation Inferred from electronic annotation. Source: Compara negative regulation of transcription elongation from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara negative regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: Compara regulation of cell proliferation Inferred from electronic annotation. Source: Compara regulation of gliogenesis Inferred from electronic annotation. Source: Compara regulation of protein phosphorylation Inferred from electronic annotation. Source: Compara
Cellular_component	ESC/E(Z) complex Inferred from electronic annotation. Source: Compara pronucleus Inferred from electronic annotation. Source: Compara
Molecular_function	chromatin binding Inferred from electronic annotation. Source: Compara core promoter binding Inferred from electronic annotation. Source: Compara histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G1L7Y5 [UniParc]. Last modified October 19, 2011. Version 1. Checksum: 956B9F59D4088AED	FASTA	751	85,995
	10 20 30 40 50 60 MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKS MFSSNRQKIL ERTEILNQEW 70 80 90 100 110 120 KQRRIQPVHI LTSVSSLRGT RECSVTSDLD FPTQVIPLKT LNAVASVPIM YSWSPLQQNF 130 140 150 160 170 180 MVEDETVLHN IPYMGDEVLD QDGTFIEELI KNYDGKVHGD RECGFINDEI FVELVNALGQ 190 200 210 220 230 240 YNDDDDDDDG DDPDEREEKQ KDLEENRDDK ESRPPRKFPS DKIFEAISSM FPDKGTAEEL 250 260 270 280 290 300 KEKYKELTEQ QLPGALPPEC TPNIDGPNAK SVQREQSLHS FHTLFCRRCF KYDCFLHRKC 310 320 330 340 350 360 NYSFHATPNT YKRKNTETAL DNKPCGPQCY QHLEGAKEFA AALTAERIKT PPKRPGGRRR 370 380 390 400 410 420 GRLPNNSSRP STPTINVLES KDTDSDREAG TETGGENNDK EEEEKKDETS SSSEANSRCQ 430 440 450 460 470 480 TPIKMKPNIE PPENVEWSGA EASMFRVLIG TYYDNFCAIA RLIGTKTCRQ VYEFRVKESS 490 500 510 520 530 540 IIAPAPAEDV DTPPRKKKRK HRLWAAHCRK IQLKKDGSSN HVYNYQPCDH PRQPCDSSCP 550 560 570 580 590 600 CVIAQNFCEK FCQCSSECQN RFPGCRCKAQ CNTKQCPCYL AVRECDPDLC LTCGAADHWD 610 620 630 640 650 660 SKNVSCKNCS IQRGSKKHLL LAPSDVAGWG IFIKDPVQKN EFISEYCGEI ISQDEADRRG 670 680 690 700 710 720 KVYDKYMCSF LFNLNNDFVV DATRKGNKIR FANHSVNPNC YAKVMMVNGD HRIGIFAKRA 730 740 750 IQTGEELFFD YRYSQADALK YVGIEREMEI P

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence and de novo assembly of the giant panda genome." Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J. , Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L., Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J., Wang J. Nature 463:311-317(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (SEP-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ACTA01090061 Genomic DNA. No translation available. ACTA01098061 Genomic DNA. No translation available. ACTA01106061 Genomic DNA. No translation available.
RefSeq	XP_002923814.1. XM_002923768.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSAMET00000003127; ENSAMEP00000003001; ENSAMEG00000002791.
GeneID	100466177.
KEGG	aml:100466177.
Organism-specific databases
CTD	2146.
Phylogenomic databases
GeneTree	ENSGT00700000104213.
KO	K11430.
OMA	NRDDKES.
Family and domain databases
InterPro	IPR026489. CXC_dom. IPR021654. EZH2_WD-Binding. IPR001005. SANT/Myb. IPR001214. SET_dom. [Graphical view]
Pfam	PF11616. EZH2_WD-Binding. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00717. SANT. 2 hits. SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS51633. CXC. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G1L7Y5_AILME

Accession

Primary (citable) accession number: G1L7Y5

Entry history

Integrated into UniProtKB/TrEMBL:	October 19, 2011
Last sequence update:	October 19, 2011
Last modified:	March 6, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)