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Protein

RuvB-like helicase

Gene

RUVBL1

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationSAAS annotation, Hydrolase
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, Transcription, Transcription regulationUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RuvB-like helicaseUniRule annotation (EC:3.6.4.12UniRule annotation)
Gene namesi
Name:RUVBL1Imported
OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
Taxonomic identifieri28377 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
Proteomesi
  • UP000001646 Componenti: Chromosome 2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSACAG00000007201.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi28377.ENSACAP00000007077.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 365AAAInterPro annotationAdd BLAST304

Sequence similaritiesi

Belongs to the RuvB family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1942. Eukaryota.
COG1224. LUCA.
GeneTreeiENSGT00890000139499.
InParanoidiG1KGA7.
KOiK04499.
OrthoDBiEOG091G07C9.
TreeFamiTF300457.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR027238. RuvB-like.
IPR037938. RUVBL1.
IPR010339. TIP49_C.
PANTHERiPTHR11093. PTHR11093. 1 hit.
PTHR11093:SF6. PTHR11093:SF6. 1 hit.
PfamiView protein in Pfam
PF06068. TIP49. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.

Sequencei

Sequence statusi: Complete.

G1KGA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIEEVKSTS KTQRIAAHSH VKGLGLDEGG AAKAAAAGLV GQENAREACG
60 70 80 90 100
VIVELIKSKK MAGRAVLLAG PPGTGKTALA LAIAQELGSK VPFCPMVGSE
110 120 130 140 150
VYSTEIKKTE VLMENFRRAI GLRIKETKEV YEGEVTELTP CETENPMGGY
160 170 180 190 200
GKTISHVIIG LKTAKGTKQL KLDPSIFESL QKERVEAGDV IYIEANSGAV
210 220 230 240 250
KRQGRCDTYA TEFDLEAEEY VPLPKGDVHK KKEIIQDVTL HDLDVANARP
260 270 280 290 300
QGGQDILSMM GQLMKPKKTE ITDKLRGEIN KVVNKYIDQG IAELVPGVLF
310 320 330 340 350
VDEVHMLDIE CFTYLHRALE SSIAPIVIFA SNRGNCVIRG TEDIISPHGI
360 370 380 390 400
PLDLLDRVMI IRTMLYTPQE MKQIIKLRAQ TESINISEEA LNHLGEIGTK
410 420 430 440 450
TTLRYAVQLL TPANLLAKIN GKDSIEKEHV EEINELFYDA KSSAKILADQ

QEKYMK
Length:456
Mass (Da):50,120
Last modified:June 26, 2013 - v2
Checksum:iDE2AA6D3CA8DB100
GO

Sequence databases

RefSeqiXP_003217773.1. XM_003217725.3.

Genome annotation databases

EnsembliENSACAT00000007229; ENSACAP00000007077; ENSACAG00000007201.
GeneIDi100567576.
KEGGiacs:100567576.

Similar proteinsi

Entry informationi

Entry nameiG1KGA7_ANOCA
AccessioniPrimary (citable) accession number: G1KGA7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: March 28, 2018
This is version 50 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported