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Protein
Submitted name:

Optineurin

Gene

OPTN

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
OptineurinImported
Gene namesi
Name:OPTNImported
OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
Taxonomic identifieri28377 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
Proteomesi
  • UP000001646 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSACAG00000001364

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi28377.ENSACAP00000001260

Structurei

3D structure databases

ProteinModelPortaliG1K9C2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini518 – 548CCHC NOA-typeInterPro annotationAdd BLAST31

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili37 – 67Sequence analysisAdd BLAST31
Coiled coili76 – 124Sequence analysisAdd BLAST49
Coiled coili129 – 170Sequence analysisAdd BLAST42
Coiled coili176 – 196Sequence analysisAdd BLAST21
Coiled coili224 – 258Sequence analysisAdd BLAST35
Coiled coili293 – 320Sequence analysisAdd BLAST28
Coiled coili331 – 358Sequence analysisAdd BLAST28
Coiled coili403 – 444Sequence analysisAdd BLAST42

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IE97 Eukaryota
ENOG410Z0DF LUCA
GeneTreeiENSGT00530000063808
InParanoidiG1K9C2
KOiK19946
OrthoDBiEOG091G0576
TreeFamiTF326608

Family and domain databases

InterProiView protein in InterPro
IPR032419 CC2-LZ_dom
IPR021063 NEMO_N
IPR034735 NEMO_ZF
IPR032939 Optineurin
PANTHERiPTHR31553:SF2 PTHR31553:SF2, 1 hit
PfamiView protein in Pfam
PF16516 CC2-LZ, 1 hit
PF11577 NEMO, 1 hit
PROSITEiView protein in PROSITE
PS51801 ZF_CCHC_NOA, 1 hit

Sequencei

Sequence statusi: Complete.

G1K9C2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSRPLNGLA ENGQHQETEV GNGHPNVPPP VPGAATVEEM VQQMKELITE
60 70 80 90 100
NNELKEAVRQ HNQAMKDRFE NLSEWSEKLK EEREFYEIKF KEARQCLASK
110 120 130 140 150
CVENETLKKQ LQTFEEKGED LTNGCTVSKK EMAQELEQLK MQVTKLQAEK
160 170 180 190 200
ADLVAIISEL QLKLNSATAE DSFVEIRMHE EEVNGALKEN QDLSDKRMGD
210 220 230 240 250
TPTYVRSRSV DEAKKYLQTE ELTVSQLLHS LRNETQKREA LEKEVQELKD
260 270 280 290 300
RALRMEYTTD EKGSQTEHEE EEAKMGDEVE TLSLQVSALF KELQDTHAKL
310 320 330 340 350
KEAEVIQKKL QEKCQVLEHQ QSANAGDQDE KQQLLYTIKK LELQVESMQS
360 370 380 390 400
EIRLEQAKTS DEKAKYNKLQ DIYNKLLPEL TNAKQTVEEL KMKEAESVDK
410 420 430 440 450
TVADKLIHKL DLAEKALATK QSQIDEMKQT IAKQEEELET VAVLRAQMEV
460 470 480 490 500
YCSDFHAERA AREKIHEEKE QLAVQLTYLL TEKQQHEGPG RNSLAEMQTR
510 520 530 540
HGTRLPSGTE SEDWQQQQRN IPAQSCPKCG MILPDIDTLQ IHVMDCII
Length:548
Mass (Da):62,915
Last modified:June 26, 2013 - v2
Checksum:i041513DC111E80B3
GO

Sequence databases

RefSeqiXP_008109659.1, XM_008111452.2

Genome annotation databases

EnsembliENSACAT00000001293; ENSACAP00000001260; ENSACAG00000001364
GeneIDi100560322
KEGGiacs:100560322

Similar proteinsi

Entry informationi

Entry nameiG1K9C2_ANOCA
AccessioniPrimary (citable) accession number: G1K9C2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: April 25, 2018
This is version 46 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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