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Protein

DNA ligase

Gene

NDAI0A01940

Organism
Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639) (Saccharomyces dairenensis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:NDAI0A01940Imported
Ordered Locus Names:NDAI_0A01940Imported
OrganismiNaumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639) (Saccharomyces dairenensis)Imported
Taxonomic identifieri1071378 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNaumovozyma
ProteomesiUP000000689 Componenti: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi1071378.XP_003667595.1.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0W3G4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRQLGTTRI LLPNLRPIRY ITMPPATPSS SSSSSSSSAR ENNVSKGRKQ
60 70 80 90 100
QATLGRFFSS INHKKPTKDT ALKNESKEET KEENKDDSDS IPRKKIRLST
110 120 130 140 150
SSSSPSIMAE SKPKSPIKLN TERSSSPASA SASTTPTPIV ADHTLDPKTA
160 170 180 190 200
VSKPFLCAIP YKEVCQLFQE IETTSSRLSI IKLCSDFLIK IMKQDPQNLI
210 220 230 240 250
PVTYLFINKL GPDYEPGLEL GLGEGLLMKT ISESCGKSLT QIRAQYRELG
260 270 280 290 300
DLGQIALEAR NVQPTMFKPK PLTVGEVFNN LKMIAKAAGK DSQTKKIKLI
310 320 330 340 350
KRMLTACEDG VEAKFLIRSL ESKLRIGLAE KTVLISLSKA LLVKEFDANK
360 370 380 390 400
DFDMELLETA EGKIRDAFCQ VPNYEIVINS CLQYGIMNLN EHCSLRPGIP
410 420 430 440 450
LKPMLAKPTK AINEILDRFQ GETFTSEYKY DGERAQVHLL EDGTMRIYSR
460 470 480 490 500
NGENMTERYP EIHIGDFVKD RNETKTLILD CEAVAWDKEQ QKILPFQVLS
510 520 530 540 550
TRKRKDVLAK DVKVRVCLFA FDILCHNSNK LINYSLKERR EILHRVTTPA
560 570 580 590 600
PGEFQYATEL TTSNLDELQK FLDQSVNDSC EGLMVKMLEG EESHYEPSKR
610 620 630 640 650
SRNWLKLKKD YLEGIGDSLD LCVLGAYYGR GKRTGTYGGF LLGCYNDNTG
660 670 680 690 700
EFETCCKIGT GFSDEMLQQL HEKLKATVID GPKATYIYDS SAEPDVWFEP
710 720 730 740 750
SLLFEVLTAD LSLSPIYKAG SSAYDKGVSL RFPRFIRIRE DKGVEDATSS
760
EQIIELYENQ SHRSS
Length:765
Mass (Da):85,961
Last modified:October 19, 2011 - v1
Checksum:iB2183F7D9EE8185B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE580267 Genomic DNA. Translation: CCD22352.1.
RefSeqiXP_003667595.1. XM_003667547.1.

Genome annotation databases

GeneIDi11494225.
KEGGindi:NDAI_0A01940.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE580267 Genomic DNA. Translation: CCD22352.1.
RefSeqiXP_003667595.1. XM_003667547.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1071378.XP_003667595.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11494225.
KEGGindi:NDAI_0A01940.

Phylogenomic databases

KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolutionary erosion of yeast sex chromosomes by mating-type switching accidents."
    Gordon J.L., Armisen D., Proux-Wera E., Oheigeartaigh S.S., Byrne K.P., Wolfe K.H.
    Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639Imported.

Entry informationi

Entry nameiG0W3G4_NAUDC
AccessioniPrimary (citable) accession number: G0W3G4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 24, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.