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G0VQJ7 (G0VQJ7_MEGEL) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase RuleBase RU000608 HAMAP-Rule MF_01201
EC=5.1.1.1 RuleBase RU000608 HAMAP-Rule MF_01201
Gene names
ORF Names:MELS_1476 EMBL CCC73697.1
OrganismMegasphaera elsdenii DSM 20460 EMBL CCC73697.1
Taxonomic identifier1064535 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Negativicutes › Selenomonadales › Veillonellaceae › Megasphaera ›

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU000608 HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000608 HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 HAMAP-Rule MF_01201 SAAS SAAS020622

Sequence similarities

Belongs to the alanine racemase family. RuleBase RU004188 HAMAP-Rule MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site461Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2761Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1451Substrate By similarity HAMAP-Rule MF_01201
Binding site3241Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue461N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
G0VQJ7 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: 62E05F70386760BB

FASTA39944,739
        10         20         30         40         50         60 
MNAYESTMNF TRRAVWAQID LDAAAHNMRQ IRKHVGPDVK IAAVVKANAY GHGSVELAKT 

        70         80         90        100        110        120 
FAENGADCFA VSSLDEAVEL RRYAHIDKEI FILGHTDARR TEELLTYDIE PAVFNLKNAE 

       130        140        150        160        170        180 
FFSQEAQRLG KTLRVHIAVD TGMSRVGFQV NEFSVSEIKA IAALPNIEIR GMFTHFAVSD 

       190        200        210        220        230        240 
IKDKTFTREQ YGHFRWMCKR MEEEGIHIAL RHCCNSAAAL ELPEYYCDMV RPGIIMYGCE 

       250        260        270        280        290        300 
PSPDVDIKPY DLRPVMSLRC CIAHVKLIDA GATVSYGRHY TAPSRRKIAT LPVGYADGYS 

       310        320        330        340        350        360 
RILSGKVDVL YHGHRVPQVG AICMDQCMID VSGEANVHAG DEVVLFGRQG DSFIPIEEIA 

       370        380        390 
AACGTINYEI MCDISRRVPR VYMKNGKVVG REEYLFDKP

« Hide

References

[1]"Genome sequence of the ruminal bacterium Megasphaera elsdenii."
Marx H., Graf A.B., Tatto N., Thallinger G.G., Mattanovich D., Sauer M.
J. Bacteriol. 193:5578-5579(2011)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DSM 20460 EMBL CCC73697.1.
[2]Graf A.
Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DSM 20460 EMBL CCC73697.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		HE576794 Genomic DNA. Translation: CCC73697.1.
RefSeqYP_004766524.1. NC_015873.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCC73697; CCC73697; MELS_1476.
GeneID11183414.
KEGGmed:MELS_1476.

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0VQJ7_MEGEL
AccessionPrimary (citable) accession number: G0VQJ7
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: May 29, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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