SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

G0VA57

- G0VA57_NAUCC

UniProt

G0VA57 - G0VA57_NAUCC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Histone-lysine N-methyltransferase, H3 lysine-4 specific
Gene
NCAS0B07030, NCAS_0B07030
Organism
Naumovozyma castellii (strain ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].UniRule annotationSAAS annotations

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, MethyltransferaseUniRule annotationSAAS annotations, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferase, H3 lysine-4 specificUniRule annotation (EC:2.1.1.43UniRule annotation)
Gene namesi
Name:NCAS0B07030Imported
Ordered Locus Names:NCAS_0B07030Imported
OrganismiNaumovozyma castellii (strain ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii)Imported
Taxonomic identifieri1064592 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNaumovozyma
ProteomesiUP000001640: Chromosome 2

Subcellular locationi

Nucleus By similarity UniRule annotation

GO - Cellular componenti

  1. Set1C/COMPASS complex Source: InterPro
  2. chromosome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeUniRule annotation, NucleusUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Component of the COMPASS (Set1C) complex By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotations
Contains post-SET domain.SAAS annotations

Phylogenomic databases

KOiK11422.
OrthoDBiEOG7P8PH3.

Family and domain databases

InterProiIPR024657. COMPASS_Set1_N-SET.
IPR017111. Hist_H3-K4_MeTrfase_1_fun.
IPR003616. Post-SET_dom.
IPR024636. SET_assoc.
IPR001214. SET_dom.
[Graphical view]
PfamiPF11764. N-SET. 1 hit.
PF00856. SET. 1 hit.
PF11767. SET_assoc. 1 hit.
[Graphical view]
PIRSFiPIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS51572. SAM_MT43_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0VA57-1 [UniParc]FASTAAdd to Basket

« Hide

MSGYHRRSYP RPPSSSHRPH GSAPNHQGPP YQEEREPSRS RYNNDGQGSF     50
QETRYSGERE SIGHRYQQPP SRVYKDQKHP DSGRVPYAAR SIRRAIDEHA 100
NTRPQPFFPT RDSRYSQGNS SPTAHVPLKI AKSVSSAGKP VRSLHSRPAP 150
IIRYSEVTNL TAKYHYFDPV SKKLIHKDEM STWNQKGKYP ITGFVTILDS 200
EQHPMIQARN PEIKSIDPRK LTSPTASISH RKLRNNLTNV ARIVYDKYSV 250
GPPPPCAIIV SPTSIINNTM IQDISIKNYF KKFGVISHFE SFNDPNSALP 300
LHIYLIKYTA PNGKLSNLDI PVKSAYQAVK EFKEKGCFIM GSNFNVALNK 350
EKLLEDIKTT LVEENIKKAK QLSAVAISTE KKDRAPIAKN QKITMERPKR 400
SIPYDLARAV NNKPCLFVSR VFMALHGFRT EDFKYKLRRY RYSKFLDHIT 450
GLYIVFGDLL ECKKCFELES GKMTLVSRSR RIPIEIRFVL IPPVDQLPTR 500
FGGFGKSTNL SPSTSSASHV KVYKTKDELI NATVKYILKD LKSILDTDIR 550
KRLIGPTVFD TLNPTNFPEL MSKKESKERA KQNAIETAAV EQKKLRESTN 600
QDFDIFNLYG GYTRKAIKKR RTSELSDISE SISLKKKKLA RPMAHLLNED 650
IGSKENTPTL ESATPFDEFD NDHDLLSSTS SSEAEDGFID DKQKVLTNES 700
PVTTPETPQD DSLLFSSSKP PKVDVTADLY KPSATEFPET VYKEDLSILK 750
LSTPLSIVDL QNMVRDDEDL FLLKELVAYK EPNTVNAADE CLEYAIWKLR 800
EWKKNDTLIK ENQLKLNEVP FAPALKIKNG PFKAENIRKV PDRLKNCYLP 850
HRRKLHQPLN TVNQHNTESV DKENSPEKLS KREDTVKPEP SESVVAQEIS 900
SSRDNRASNR RFQQNIEAQR AAIGTESELL SLNQLNKRKK PVTFARSAIH 950
NWGLYALEPI AAREMIIEYV GESIRQPVAE MRERRYLKSG IGSSYLFRVD 1000
ENNVIDATKK GGIARFINHC CDPSCTAKII KVGGKRRIVI YALRDIAANE 1050
ELTYDYKFER ELDAEERLPC YCGSVNCKGF LN 1082
Length:1,082
Mass (Da):123,202
Last modified:October 19, 2011 - v1
Checksum:i8DBDE110CD02CA53
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE576753 Genomic DNA. Translation: CCC68787.1.
RefSeqiXP_003675158.1. XM_003675110.1.

Genome annotation databases

GeneIDi11525032.
KEGGincs:NCAS_0B07030.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE576753 Genomic DNA. Translation: CCC68787.1 .
RefSeqi XP_003675158.1. XM_003675110.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 11525032.
KEGGi ncs:NCAS_0B07030.

Phylogenomic databases

KOi K11422.
OrthoDBi EOG7P8PH3.

Family and domain databases

InterProi IPR024657. COMPASS_Set1_N-SET.
IPR017111. Hist_H3-K4_MeTrfase_1_fun.
IPR003616. Post-SET_dom.
IPR024636. SET_assoc.
IPR001214. SET_dom.
[Graphical view ]
Pfami PF11764. N-SET. 1 hit.
PF00856. SET. 1 hit.
PF11767. SET_assoc. 1 hit.
[Graphical view ]
PIRSFi PIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
SMARTi SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
PROSITEi PS50868. POST_SET. 1 hit.
PS51572. SAM_MT43_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Evolutionary erosion of yeast sex chromosomes by mating-type switching accidents."
    Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P., Wolfe K.H.
    Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL Y-12630.
  2. "Genome sequence of Naumovozyma castellii."
    Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P., Wolfe K.H.
    Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Type strain:CBS 4309.

Entry informationi

Entry nameiG0VA57_NAUCC
AccessioniPrimary (citable) accession number: G0VA57
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: May 14, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi