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G0THN8

- G0THN8_MYCCP

UniProt

G0THN8 - G0THN8_MYCCP

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Protein
2-phospho-L-lactate transferase
Gene
fbiA, cofD, MCAN_32801
Organism
Mycobacterium canettii (strain CIPT 140010059)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP By similarity.UniRule annotation

Catalytic activityi

(2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = guanosine 5'-phosphate + coenzyme F420-0.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. phosphotransferase activity, for other substituted phosphate groups Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. cofactor biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation

Enzyme and pathway databases

BioCyciMCAN1048245:GJCJ-3313-MONOMER.
UniPathwayiUPA00071.

Names & Taxonomyi

Protein namesi
Recommended name:
2-phospho-L-lactate transferaseUniRule annotation (EC:2.7.8.28UniRule annotation)
Alternative name(s):
LPPG:FO 2-phospho-L-lactate transferase
Gene namesi
Name:fbiAImported
Synonyms:cofDUniRule annotation
Ordered Locus Names:MCAN_32801Imported
OrganismiMycobacterium canettii (strain CIPT 140010059)Imported
Taxonomic identifieri1048245 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000008896: Chromosome

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliG0THN8.
SMRiG0THN8. Positions 5-297.

Family & Domainsi

Sequence similaritiesi

Belongs to the CofD family.UniRule annotation

Phylogenomic databases

KOiK11212.
OMAiWWVRHRA.

Family and domain databases

HAMAPiMF_01257. CofD.
InterProiIPR002882. CofD/UPF0052.
IPR010115. LPPG-Fo_P-lactate_Trfase.
[Graphical view]
PfamiPF01933. UPF0052. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01819. F420_cofD. 1 hit.

Sequencei

Sequence statusi: Complete.

G0THN8-1 [UniParc]FASTAAdd to Basket

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MKVTVLAGGV GGARFLLGVQ QLLGLGQFAA NSAHSDADHQ LSAVVNVGDD    50
AWIHGLRVCP DLDTCMYTLG GGVDPQRGWG QRDETWHAMQ ELVRYGVQPD 100
WFELGDRDLA THLVRTQMLQ AGYPLSQITE ALCDRWQPGA RLLPATDDRC 150
ETHVVITDPV DESRKAIHFQ EWWVRYRAQV PTHSFAFVGA EKSSAATEAI 200
AALADADIIM LAPSNPVVSI GAILAVPGIR AALREATAPI VGYSPIIGEK 250
PLRGMADTCL SVIGVDSTAA AVGRHYGARC ATGILDCWLV HDGDHAEIDG 300
VTVRSVPLLM TDPNATAEMV RAGCDLAGVV A 331
Length:331
Mass (Da):35,335
Last modified:October 19, 2011 - v1
Checksum:i4D144F9A17F792C6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE572590 Genomic DNA. Translation: CCC45611.1.
RefSeqiYP_004746691.1. NC_015848.1.

Genome annotation databases

EnsemblBacteriaiCCC45611; CCC45611; MCAN_32801.
GeneIDi10987268.
KEGGimce:MCAN_32801.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE572590 Genomic DNA. Translation: CCC45611.1 .
RefSeqi YP_004746691.1. NC_015848.1.

3D structure databases

ProteinModelPortali G0THN8.
SMRi G0THN8. Positions 5-297.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCC45611 ; CCC45611 ; MCAN_32801 .
GeneIDi 10987268.
KEGGi mce:MCAN_32801.

Phylogenomic databases

KOi K11212.
OMAi WWVRHRA.

Enzyme and pathway databases

UniPathwayi UPA00071 .
BioCyci MCAN1048245:GJCJ-3313-MONOMER.

Family and domain databases

HAMAPi MF_01257. CofD.
InterProi IPR002882. CofD/UPF0052.
IPR010115. LPPG-Fo_P-lactate_Trfase.
[Graphical view ]
Pfami PF01933. UPF0052. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01819. F420_cofD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CIPT 140010059Imported.

Entry informationi

Entry nameiG0THN8_MYCCP
AccessioniPrimary (citable) accession number: G0THN8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 11, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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