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G0TGK8 (G0TGK8_MYCCP) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339

Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339 EMBL CCC45364.1
Ordered Locus Names:MCAN_30331 EMBL CCC45364.1
OrganismMycobacterium canettii (strain CIPT 140010059) [Complete proteome] [HAMAP] EMBL CCC45364.1
Taxonomic identifier1048245 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. HAMAP-Rule MF_00339

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. HAMAP-Rule MF_00339

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00339.

Sequence similarities

Belongs to the phosphofructokinase family. HAMAP-Rule MF_00339

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding20 – 245ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding155 – 1595ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding172 – 18817ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1281Proton acceptor By similarity HAMAP-Rule MF_00339
Binding site1631Substrate By similarity HAMAP-Rule MF_00339
Binding site2671Substrate By similarity HAMAP-Rule MF_00339
Binding site2731Substrate By similarity HAMAP-Rule MF_00339
Binding site2761Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
G0TGK8 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: 827E85916A6ECABA

FASTA34336,880
        10         20         30         40         50         60 
MRIGVLTGGG DCPGLNAVIR AVVRTCHARY GSSVVGFQNG FRGLLENRRV QLHNDDRNDR 

        70         80         90        100        110        120 
LLAKGGTMLG TARVHPDKLR AGLPQIMQTL DDNGIDVLIP IGGEGTLTAA SWLSEENVPV 

       130        140        150        160        170        180 
VGVPKTIDND IDCTDVTFGH DTALTVATEA IDRLHSTAES HERVMLVEVM GRHAGWIALN 

       190        200        210        220        230        240 
AGLASGAHMT LIPEQPFDIE EVCRLVKGRF QRGDSHFICV VAEGAKPAPG TIMLREGGLD 

       250        260        270        280        290        300 
EFGHERFTGV AAQLAVEVEK RINKDVRVTV LGHIQRGGTP TAYDRVLATR FGVNAADAAH 

       310        320        330        340 
AGEYGQMVTL RGQDIGRVPL ADAVRQLKLV PQSRYDDAAA FFG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HE572590 Genomic DNA. Translation: CCC45364.1.
RefSeqYP_004746452.1. NC_015848.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCC45364; CCC45364; MCAN_30331.
GeneID10986107.
KEGGmce:MCAN_30331.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00850.
OMAWVGLMED.

Enzyme and pathway databases

BioCycMCAN1048245:GJCJ-3063-MONOMER.
UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012829. PFK.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. SSF53784. 1 hit.
TIGRFAMsTIGR02483. PFK_mixed. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0TGK8_MYCCP
AccessionPrimary (citable) accession number: G0TGK8
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: April 16, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)