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Protein

Riboflavin biosynthesis protein

Gene

ribF

Organism
Mycobacterium canettii (strain CIPT 140010059)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + FMN = diphosphate + FAD.UniRule annotation
ATP + riboflavin = ADP + FMN.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. FMN adenylyltransferase activity Source: UniProtKB-EC
  3. riboflavin kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. FAD biosynthetic process Source: UniProtKB-UniPathway
  2. FMN biosynthetic process Source: UniProtKB-UniPathway
  3. riboflavin biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, NucleotidyltransferaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, FADUniRule annotation, Flavoprotein, FMNUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMCAN1048245:GJCJ-2842-MONOMER.
UniPathwayiUPA00276; UER00406.
UPA00277; UER00407.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin biosynthesis proteinUniRule annotation (EC:2.7.1.26UniRule annotation, EC:2.7.7.2UniRule annotation)
Gene namesi
Name:ribFImported
Ordered Locus Names:MCAN_28141Imported
OrganismiMycobacterium canettii (strain CIPT 140010059)Imported
Taxonomic identifieri1048245 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000008896 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the ribF family.UniRule annotation

Phylogenomic databases

KOiK11753.
OMAiFHFGRGR.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
3.40.50.620. 1 hit.
InterProiIPR015864. FAD_synthase.
IPR023468. Riboflavin_kinase.
IPR002606. Riboflavin_kinase_bac.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF06574. FAD_syn. 1 hit.
PF01687. Flavokinase. 1 hit.
[Graphical view]
PIRSFiPIRSF004491. FAD_Synth. 1 hit.
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.
TIGRFAMsiTIGR00083. ribF. 1 hit.

Sequencei

Sequence statusi: Complete.

G0TF93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRRLAIVQR WRGQDEIPTD WGRCVLTIGV FDGVHRGHAE LIAHAVKAGR
60 70 80 90 100
ARGVPAVLMT FDPHPMEVVY PGSHPAQLTT LTRRAELVQD LGIEVFLVMP
110 120 130 140 150
FTTDFMKLTP DRFIHELLVE HLHVVEVVVG ENFTFGKKAA GNVDTLRRAG
160 170 180 190 200
ERFGFAVESM SLVSEHHSNE TVTFSSTYIR SCVDAGDMVA AMEALGRPHR
210 220 230 240 250
VEGVVVRGEG RGAELGFPTA NVAPPMYSAI PADGVYAAWF TVLGHGPVTG
260 270 280 290 300
TVVPGERYQA AVSVGTNPTF SGRTRTVEAF VLDTTADLYG QHVALDFVGR
310 320 330
IRGQKKFESV RQLVAAMGAD TERARDLLSR G
Length:331
Mass (Da):36,145
Last modified:October 19, 2011 - v1
Checksum:i64C0D82716B255BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE572590 Genomic DNA. Translation: CCC45145.1.
RefSeqiWP_014001418.1. NC_015848.1.
YP_004746240.1. NC_015848.1.

Genome annotation databases

EnsemblBacteriaiCCC45145; CCC45145; MCAN_28141.
KEGGimce:MCAN_28141.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE572590 Genomic DNA. Translation: CCC45145.1.
RefSeqiWP_014001418.1. NC_015848.1.
YP_004746240.1. NC_015848.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCC45145; CCC45145; MCAN_28141.
KEGGimce:MCAN_28141.

Phylogenomic databases

KOiK11753.
OMAiFHFGRGR.

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406.
UPA00277; UER00407.
BioCyciMCAN1048245:GJCJ-2842-MONOMER.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
3.40.50.620. 1 hit.
InterProiIPR015864. FAD_synthase.
IPR023468. Riboflavin_kinase.
IPR002606. Riboflavin_kinase_bac.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF06574. FAD_syn. 1 hit.
PF01687. Flavokinase. 1 hit.
[Graphical view]
PIRSFiPIRSF004491. FAD_Synth. 1 hit.
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.
TIGRFAMsiTIGR00083. ribF. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The Genome of Mycobacterium Africanum West African 2 Reveals a Lineage-Specific Locus and Genome Erosion Common to the M. tuberculosis Complex."
    Bentley S.D., Comas I., Bryant J.M., Walker D., Smith N.H., Harris S.R., Thurston S., Gagneux S., Wood J., Antonio M., Quail M.A., Gehre F., Adegbola R.A., Parkhill J., de Jong B.C.
    PLoS Negl. Trop. Dis. 6:e1552-e1552(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CIPT 140010059Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CIPT 140010059Imported.

Entry informationi

Entry nameiG0TF93_MYCCP
AccessioniPrimary (citable) accession number: G0TF93
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: April 29, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.