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G0LLH9

- G0LLH9_HALWC

UniProt

G0LLH9 - G0LLH9_HALWC

Protein

DNA ligase

Gene

ligB2

Organism
Haloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    Cofactori

    Divalent metal cations.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei312 – 3121ATPUniRule annotation
    Active sitei314 – 3141N6-AMP-lysine intermediateUniRule annotation
    Binding sitei319 – 3191ATPUniRule annotation
    Binding sitei334 – 3341ATPUniRule annotation
    Binding sitei363 – 3631ATPUniRule annotation
    Binding sitei403 – 4031ATPUniRule annotation
    Binding sitei476 – 4761ATPUniRule annotation
    Binding sitei482 – 4821ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
    4. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. DNA ligation involved in DNA repair Source: InterPro
    4. DNA recombination Source: UniProtKB-HAMAP
    5. DNA replication Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    Cell cycle, Cell divisionUniRule annotation, DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciHWAL768065:GLDV-2161-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Alternative name(s):
    Polydeoxyribonucleotide synthase [ATP]UniRule annotation
    Gene namesi
    Name:ligB2Imported
    Synonyms:ligUniRule annotation
    Ordered Locus Names:Hqrw_2987Imported
    OrganismiHaloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23)Imported
    Taxonomic identifieri768065 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloquadratum
    ProteomesiUP000007954: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK10747.
    OMAiARVQVHK.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPiMF_00407. DNA_ligase.
    InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G0LLH9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQFDDFANHV ITIEAESADL EITSLVSKLL TTAGNMDDKT LSIVVRFIKG    50
    TVFPAWSSQT LDIGPALLHT TIAQAAGPNV DSADVENRLA EYGEIGAVAA 100
    SYDLNGQQGL SAFTPSTPDS LTVGHVDKTL RAVASASGDG SESRRRNLLF 150
    GLFSQASSSE ARVLARLILG EMRIGVGTGT VRDAIISGFI EPAADADKKT 200
    LESREDAESV PPASQPEMTN KISGDTSPNT SESVQTKESD PDTSSNVDPS 250
    AVVERALQVS NDYGMVATIA RNQGQAGLID ISLEVGRPIQ AMLAQAADGV 300
    DAVDTWDAVA IETKFDGARV QIHTDGESVS LYSRNMEDVT DPLPEIVEFI 350
    SQKVTVPAIL DAEVVAVSDD DDPLAFQEVL RRFRRKYDID AMRESVNLNV 400
    YVFDCLHIDD ADLLDIPLRE RRERLRELFN TTDALSPFQL TTDPNVIAQA 450
    RSKALSNGHE GVMLKDPDST YNPGSRGQHW LKHKPDVETL DLVVTGAEWG 500
    EGRRANVFGT FVVSARTTAD EQQFNSLGKV ATGLTDDQLT TLTEQLRPHV 550
    RSEDGQTVMI EPAIVVEVGY EEIQRSPTYD SGFALRFPRV VGIRHDKAIS 600
    DVDSLSRIKH LTTGESPD 618
    Length:618
    Mass (Da):67,028
    Last modified:October 19, 2011 - v1
    Checksum:i024B04FA96F60CED
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FR746099 Genomic DNA. Translation: CCC40785.1.
    RefSeqiWP_014556319.1. NC_017459.1.
    YP_005840430.1. NC_017459.1.

    Genome annotation databases

    EnsemblBacteriaiCCC40785; CCC40785; Hqrw_2987.
    GeneIDi12447762.
    KEGGihwc:Hqrw_2987.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FR746099 Genomic DNA. Translation: CCC40785.1 .
    RefSeqi WP_014556319.1. NC_017459.1.
    YP_005840430.1. NC_017459.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CCC40785 ; CCC40785 ; Hqrw_2987 .
    GeneIDi 12447762.
    KEGGi hwc:Hqrw_2987.

    Phylogenomic databases

    KOi K10747.
    OMAi ARVQVHK.

    Enzyme and pathway databases

    BioCyci HWAL768065:GLDV-2161-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPi MF_00407. DNA_ligase.
    InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 16854 / JCM 12705 / C23Imported.

    Entry informationi

    Entry nameiG0LLH9_HALWC
    AccessioniPrimary (citable) accession number: G0LLH9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3