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G0LLH9 (G0LLH9_HALWC) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
DNA ligase HAMAP-Rule MF_00407 RuleBase RU000617

EC=6.5.1.1 HAMAP-Rule MF_00407 RuleBase RU000617
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:ligB2 EMBL CCC40785.1
Synonyms:lig HAMAP-Rule MF_00407
Ordered Locus Names:Hqrw_2987 EMBL CCC40785.1
OrganismHaloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23) [Complete proteome] [HAMAP] EMBL CCC40785.1
Taxonomic identifier768065 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloquadratum

Protein attributes

Sequence length618 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407 RuleBase RU000617

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site3141N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site3121ATP By similarity HAMAP-Rule MF_00407
Binding site3191ATP By similarity HAMAP-Rule MF_00407
Binding site3341ATP By similarity HAMAP-Rule MF_00407
Binding site3631ATP By similarity HAMAP-Rule MF_00407
Binding site4031ATP By similarity HAMAP-Rule MF_00407
Binding site4761ATP By similarity HAMAP-Rule MF_00407
Binding site4821ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
G0LLH9 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: 024B04FA96F60CED

FASTA61867,028
        10         20         30         40         50         60 
MQFDDFANHV ITIEAESADL EITSLVSKLL TTAGNMDDKT LSIVVRFIKG TVFPAWSSQT 

        70         80         90        100        110        120 
LDIGPALLHT TIAQAAGPNV DSADVENRLA EYGEIGAVAA SYDLNGQQGL SAFTPSTPDS 

       130        140        150        160        170        180 
LTVGHVDKTL RAVASASGDG SESRRRNLLF GLFSQASSSE ARVLARLILG EMRIGVGTGT 

       190        200        210        220        230        240 
VRDAIISGFI EPAADADKKT LESREDAESV PPASQPEMTN KISGDTSPNT SESVQTKESD 

       250        260        270        280        290        300 
PDTSSNVDPS AVVERALQVS NDYGMVATIA RNQGQAGLID ISLEVGRPIQ AMLAQAADGV 

       310        320        330        340        350        360 
DAVDTWDAVA IETKFDGARV QIHTDGESVS LYSRNMEDVT DPLPEIVEFI SQKVTVPAIL 

       370        380        390        400        410        420 
DAEVVAVSDD DDPLAFQEVL RRFRRKYDID AMRESVNLNV YVFDCLHIDD ADLLDIPLRE 

       430        440        450        460        470        480 
RRERLRELFN TTDALSPFQL TTDPNVIAQA RSKALSNGHE GVMLKDPDST YNPGSRGQHW 

       490        500        510        520        530        540 
LKHKPDVETL DLVVTGAEWG EGRRANVFGT FVVSARTTAD EQQFNSLGKV ATGLTDDQLT 

       550        560        570        580        590        600 
TLTEQLRPHV RSEDGQTVMI EPAIVVEVGY EEIQRSPTYD SGFALRFPRV VGIRHDKAIS 

       610 
DVDSLSRIKH LTTGESPD 

« Hide

References

[1]"Haloquadratum walsbyi: limited diversity in a global pond."
Dyall-Smith M., Pfeiffer F., Klee K., Palm P., Gross K., Schuster S.C., Rampp M., Oesterhelt D.
PLoS ONE 6:E20968-E20968(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 16854 / JCM 12705 / C23.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FR746099 Genomic DNA. Translation: CCC40785.1.
RefSeqYP_005840430.1. NC_017459.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCC40785; CCC40785; Hqrw_2987.
GeneID12447762.
KEGGhwc:Hqrw_2987.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK10747.
OMAGRPRPFQ.

Enzyme and pathway databases

BioCycHWAL768065:GLDV-2161-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0LLH9_HALWC
AccessionPrimary (citable) accession number: G0LLH9
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: February 19, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)