Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

G0LKX0

- G0LKX0_HALWC

UniProt

G0LKX0 - G0LKX0_HALWC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

DNA ligase

Gene

ligB1

Organism
Haloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

Cofactori

Note: Divalent metal cations.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei272 – 2721ATPUniRule annotation
Active sitei274 – 2741N6-AMP-lysine intermediateUniRule annotation
Binding sitei279 – 2791ATPUniRule annotation
Binding sitei294 – 2941ATPUniRule annotation
Binding sitei324 – 3241ATPUniRule annotation
Binding sitei367 – 3671ATPUniRule annotation
Binding sitei472 – 4721ATPUniRule annotation
Binding sitei478 – 4781ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
  4. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. DNA biosynthetic process Source: InterPro
  4. DNA ligation involved in DNA repair Source: InterPro
  5. DNA recombination Source: UniProtKB-HAMAP
  6. DNA replication Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

Cell cycle, Cell divisionUniRule annotation, DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHWAL768065:GLDV-1693-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]UniRule annotation
Gene namesi
Name:ligB1Imported
Synonyms:ligUniRule annotation
Ordered Locus Names:Hqrw_2571Imported
OrganismiHaloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23)Imported
Taxonomic identifieri768065 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloquadratum
ProteomesiUP000007954: Chromosome

Structurei

3D structure databases

ProteinModelPortaliG0LKX0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747.
OMAiKSASTHN.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPiMF_00407. DNA_ligase.
InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0LKX0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKYSELAEVY TDVAATSATT QKGTLLADCF LDVYNNTEKS LLPVTVRLVQ
60 70 80 90 100
GRVFARWEAA EIGVSTAGAA DAISKATGVE SEQIETWWRE EGDLGDAAAY
110 120 130 140 150
AVDDRVQQTL TATPLTVTRV YETLREVASY AGSGSQQKQR DEIAGLISDA
160 170 180 190 200
SPLAARYIVR TVTGSMRLGV GEGIVRNALA SAFLDMSDDA ADAVQRAIDL
210 220 230 240 250
TNDVAVVAQR VAEQGQPGLD DVDLELFRPI KPMLAKQAES IQTAVDELAA
260 270 280 290 300
DPKHIERNHN IELSHSGAVL IEFKYDGIRA KIHRDGDEIR VYTRRLSDVT
310 320 330 340 350
EQFPDVVSAA RDHIDAEHYI IEAELVGYDP QSNDDTPVTF QTLAQRIQRT
360 370 380 390 400
DNVATIAKSI PVTTYVFDLL ALNGESLLTD TLEMRLERLN TILSTKATSD
410 420 430 440 450
SKSASTHNAH SSTSVTTVSN DQYQSSSSLR RAQCTWATTQ TTATEFYEDA
460 470 480 490 500
LAAGHEGVMI KNPTRPYQPG SRVGYQRKIK PTMEPLDLVV TRAKWSEGRK
510 520 530 540 550
SDFLGRPYLA CRTADGNLAE VGRMHTGFTD DQLETFTNRV EPLIEHVEGR
560 570 580 590 600
EATLTPAVVL AVEYEEIQIS STYDSGYALR FPRLKQIRHD CDPSQADSLE
610
RVERLYEQQS LDESQTSV
Length:618
Mass (Da):68,156
Last modified:October 19, 2011 - v1
Checksum:i9A541CF94B3C8A1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR746099 Genomic DNA. Translation: CCC40410.1.
RefSeqiWP_014556038.1. NC_017459.1.
YP_005840086.1. NC_017459.1.

Genome annotation databases

EnsemblBacteriaiCCC40410; CCC40410; Hqrw_2571.
GeneIDi12447293.
KEGGihwc:Hqrw_2571.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR746099 Genomic DNA. Translation: CCC40410.1 .
RefSeqi WP_014556038.1. NC_017459.1.
YP_005840086.1. NC_017459.1.

3D structure databases

ProteinModelPortali G0LKX0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCC40410 ; CCC40410 ; Hqrw_2571 .
GeneIDi 12447293.
KEGGi hwc:Hqrw_2571.

Phylogenomic databases

KOi K10747.
OMAi KSASTHN.

Enzyme and pathway databases

BioCyci HWAL768065:GLDV-1693-MONOMER.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPi MF_00407. DNA_ligase.
InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16854 / JCM 12705 / C23Imported.

Entry informationi

Entry nameiG0LKX0_HALWC
AccessioniPrimary (citable) accession number: G0LKX0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 26, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3