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G0L1J5 (G0L1J5_ZOBGA) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddlA EMBL CAZ94749.1
Synonyms:ddl HAMAP-Rule MF_00047
Ordered Locus Names:zobellia_683 EMBL CAZ94749.1
OrganismZobellia galactanivorans (strain DSM 12802 / CIP 106680 / NCIMB 13871 / Dsij) [Complete proteome] [HAMAP] EMBL CAZ94749.1
Taxonomic identifier63186 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeZobellia

Protein attributes

Sequence length326 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain121 – 320200ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding149 – 20456ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2751Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2871Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2871Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2891Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
G0L1J5 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: E60DDC927C363F69

FASTA32636,821
        10         20         30         40         50         60 
MKKNIAIIMG GYSSEYKISL NSGNVVHRYL NKERFNTYRI HIFKEKWVYV DANEKEHPVN 

        70         80         90        100        110        120 
KADFTVNTDQ GHVAFDCVFN AIHGTPGEDG LMQAYFELLG IPQTSCDYYQ SALTFNKRDL 

       130        140        150        160        170        180 
LSVLKPYGIK SAPSYYLNLG DPIDEEAIIA KVGLPCFVKA NKAGSSFGIS KVHEKENLRS 

       190        200        210        220        230        240 
AIDKAYQEDD EIIIEGFLDG TEVSVGVITY KGETKVLPIT EIVSENDFFD YEAKYQGKSQ 

       250        260        270        280        290        300 
EITPARISKI QRDKVEEMAK RAYEVLKMKG YSRSEFIFIE DEPYMLEMNT TPGLTTESIL 

       310        320 
PQQAEKAGIS LEELFTSAVD EALNQK 

« Hide

References

[1]"Complete genome sequence of Zobellia galactanivorans Dsij."
Genoscope - CEA
Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 12802 / CIP 106680 / NCIMB 13871 / Dsij.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FP476056 Genomic DNA. Translation: CAZ94749.1.
RefSeqYP_004735140.1. NC_015844.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10977252.
KEGGzga:zobellia_683.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycZGAL63186:GJN9-684-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0L1J5_ZOBGA
AccessionPrimary (citable) accession number: G0L1J5
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 11, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)