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Protein

Ribonucleoside-diphosphate reductase

Gene

BurJV3_0201

Organism
Stenotrophomonas maltophilia JV3
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.UniRule annotation

Catalytic activityi

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.UniRule annotation

Pathway:iDNA replication

This protein is involved in the pathway DNA replication, which is part of Genetic information processing.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway DNA replication and in Genetic information processing.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSMAL868597:GHCG-201-MONOMER.
UniPathwayiUPA00326.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonucleoside-diphosphate reductaseUniRule annotation (EC:1.17.4.1UniRule annotation)
Gene namesi
ORF Names:BurJV3_0201Imported
OrganismiStenotrophomonas maltophilia JV3Imported
Taxonomic identifieri868597 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeStenotrophomonasStenotrophomonas maltophilia group
ProteomesiUP000000700 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the ribonucleoside diphosphate reductase large chain family.UniRule annotation

Phylogenomic databases

KOiK00525.

Family and domain databases

InterProiIPR005144. ATP-cone.
IPR013346. NrdE_NrdA.
IPR000788. RNR_lg_C.
IPR013509. RNR_lsu_N.
IPR008926. RNR_R1-su_N.
[Graphical view]
PfamiPF03477. ATP-cone. 1 hit.
PF02867. Ribonuc_red_lgC. 1 hit.
PF00317. Ribonuc_red_lgN. 1 hit.
[Graphical view]
PRINTSiPR01183. RIBORDTASEM1.
SUPFAMiSSF48168. SSF48168. 1 hit.
TIGRFAMsiTIGR02506. NrdE_NrdA. 1 hit.
PROSITEiPS51161. ATP_CONE. 1 hit.
PS00089. RIBORED_LARGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0K4I3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTESSATIE KESEFLLTSP PTANAMSVTK RNGTTELVDL NKIVRAVQRS
60 70 80 90 100
SEGLHAVDPM RVATRTISGL YNGATTRELD ELSIRTAALL IGEEPEYGRL
110 120 130 140 150
AARLLANYIA KEVSGQEIYA FSQSVSRGHE VGLINDRLLN FVQTNARKLN
160 170 180 190 200
DAIDGALDLN FDYFGLRTLY DRYLLRHPHT RKVIETPQQF FLRIASALSE
210 220 230 240 250
DVSETLALYK RMGNLDYLPS SPTLFNSGTT HEQLSSCFLL DSPQDSLESI
260 270 280 290 300
YSKYGDIAQL SKFSGGIGVS YTRVRSRGSL IKSTNGHSNG IVPWLKTMDS
310 320 330 340 350
SVAAVNQGGK RKGAACVYLE TWHADIEDFL ELRDNTGDEA RRAHNLNLAN
360 370 380 390 400
WVPDLFMKRV EADQEWSLFD PRVVPEFTDL FGEAFEQAYL QAEAQGKANR
410 420 430 440 450
TISARKLYAR MMRTLAETGN GWMTFKDKCN RASNQTLRAG NVIHLSNLCT
460 470 480 490 500
EILEVTSNDE TAVCNLGSIN LGNHFDEHNE FDFEKLAETV RLAVRQLDRV
510 520 530 540 550
IDLNFYPIET ARRANLRWRP VGLGCMGLQD VFFRKRLPFD SAEARALSKK
560 570 580 590 600
IAEAIYFHAL ETSCELAQER GKHPSFNDTR AAGGELQFDA WNVVPEDTAR
610 620 630 640 650
WDALRARIKE HGLRNSLMIA IAPTATIASI AGCYECVEPQ VSNLFKRETL
660 670 680 690 700
SGDFLQVNRY LVNELKKLGL WTPEMRDAIK LAEGSIAGVA QIPETLREVY
710 720 730 740 750
RTAWELPMRS LIDMAAERGA FIDQSASLNL FMESPNIGAM SSMYMYAWKQ
760 770 780 790 800
GIKTTYYLRS RPATKIAKTT VSAAAPAKVF SPDEAIACSL ENPEACEACQ
Length:800
Mass (Da):89,339
Last modified:October 19, 2011 - v1
Checksum:i5BE9023C469C62EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002986 Genomic DNA. Translation: AEM49537.1.
RefSeqiWP_014035599.1. NC_015947.1.

Genome annotation databases

EnsemblBacteriaiAEM49537; AEM49537; BurJV3_0201.
KEGGibuj:BurJV3_0201.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002986 Genomic DNA. Translation: AEM49537.1.
RefSeqiWP_014035599.1. NC_015947.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEM49537; AEM49537; BurJV3_0201.
KEGGibuj:BurJV3_0201.

Phylogenomic databases

KOiK00525.

Enzyme and pathway databases

UniPathwayiUPA00326.
BioCyciSMAL868597:GHCG-201-MONOMER.

Family and domain databases

InterProiIPR005144. ATP-cone.
IPR013346. NrdE_NrdA.
IPR000788. RNR_lg_C.
IPR013509. RNR_lsu_N.
IPR008926. RNR_R1-su_N.
[Graphical view]
PfamiPF03477. ATP-cone. 1 hit.
PF02867. Ribonuc_red_lgC. 1 hit.
PF00317. Ribonuc_red_lgN. 1 hit.
[Graphical view]
PRINTSiPR01183. RIBORDTASEM1.
SUPFAMiSSF48168. SSF48168. 1 hit.
TIGRFAMsiTIGR02506. NrdE_NrdA. 1 hit.
PROSITEiPS51161. ATP_CONE. 1 hit.
PS00089. RIBORED_LARGE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: JV3Imported.

Entry informationi

Entry nameiG0K4I3_STEMA
AccessioniPrimary (citable) accession number: G0K4I3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: July 22, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.