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G0JQJ6 (G0JQJ6_9GAMM) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
NADH-quinone oxidoreductase subunit H HAMAP-Rule MF_01350

EC=1.6.99.5 HAMAP-Rule MF_01350
Alternative name(s):
NADH dehydrogenase I subunit H HAMAP-Rule MF_01350
NDH-1 subunit H HAMAP-Rule MF_01350
Gene names
Name:nuoH HAMAP-Rule MF_01350
ORF Names:Acife_2547 EMBL AEM48635.1
OrganismAcidithiobacillus ferrivorans SS3 [Complete proteome] EMBL AEM48635.1
Taxonomic identifier743299 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus

Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone By similarity. HAMAP-Rule MF_01350

Catalytic activity

NADH + quinone = NAD+ + quinol. HAMAP-Rule MF_01350

Subunit structure

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex By similarity. HAMAP-Rule MF_01350

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01350.

Membrane; Multi-pass membrane protein By similarity RuleBase RU000471.

Sequence similarities

Belongs to the complex I subunit 1 family. RuleBase RU000471 HAMAP-Rule MF_01350

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane10 – 3021Helical; By similarity HAMAP-Rule MF_01350
Transmembrane82 – 10221Helical; By similarity HAMAP-Rule MF_01350
Transmembrane117 – 13721Helical; By similarity HAMAP-Rule MF_01350
Transmembrane151 – 17121Helical; By similarity HAMAP-Rule MF_01350
Transmembrane189 – 20921Helical; By similarity HAMAP-Rule MF_01350
Transmembrane247 – 26923Helical; By similarity HAMAP-Rule MF_01350
Transmembrane277 – 29721Helical; By similarity HAMAP-Rule MF_01350
Transmembrane312 – 33221Helical; By similarity HAMAP-Rule MF_01350

Sequences

Sequence LengthMass (Da)Tools
G0JQJ6 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: F352A5A8FEB8DC9B

FASTA34137,811
        10         20         30         40         50         60 
MHDFQNTAWW AILWSLIKIV IVVVPLLLGV AYLTLAERKV IGYMQVRLGP NRVGFKGSLQ 

        70         80         90        100        110        120 
PIADAIKLMF KEVIIPTNAN RFLFLAAPVL AFVPALLVWA AIPFGPGVAI SNMNAGLLYV 

       130        140        150        160        170        180 
LAIAGLGVYG IIVAGWASNS KYAFLGAMRA AAQLVAYEIA MGFALVGVLM LAQTLNLSKI 

       190        200        210        220        230        240 
VEAQAGGGFW SWYWLPLFPF FLVYFISGIA ETNRAPFDVA EGESEIVAGF HVEYSGMAFA 

       250        260        270        280        290        300 
LFFLAEYANM IFVSLLTTVL FLGGWYAPIN TPLLTWIPGI VWLLLKTAFL LYVFLWIRAT 

       310        320        330        340 
FPRYRYDQIM RLGWKVFIPV TIAWIVIVGV ALETPLRAIL R 

« Hide

References

[1]"Draft Genome of the Psychrotolerant Acidophile Acidithiobacillus ferrivorans SS3."
Liljeqvist M., Valdes J., Holmes D.S., Dopson M.
J. Bacteriol. 193:4304-4305(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: SS3 EMBL AEM48635.1.
[2]US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Liljeqvist M. expand/collapse author list , Valdes J., Holmes D., Dopson M., Woyke T.
Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: SS3 EMBL AEM48635.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002985 Genomic DNA. Translation: AEM48635.1.
RefSeqYP_004784961.1. NC_015942.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEM48635; AEM48635; Acife_2547.
GeneID11043310.
KEGGafi:Acife_2547.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00337.

Enzyme and pathway databases

BioCycAFER743299:GH39-2586-MONOMER.

Family and domain databases

HAMAPMF_01350. NDH1_NuoH.
InterProIPR001694. NADH_UbQ_OxRdtase_su1/FPO.
IPR018086. NADH_UbQ_OxRdtase_su1_CS.
[Graphical view]
PANTHERPTHR11432. PTHR11432. 1 hit.
PfamPF00146. NADHdh. 1 hit.
[Graphical view]
PROSITEPS00667. COMPLEX1_ND1_1. 1 hit.
PS00668. COMPLEX1_ND1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0JQJ6_9GAMM
AccessionPrimary (citable) accession number: G0JQJ6
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: February 19, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)