Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

G0JJY6

- G0JJY6_YERPE

UniProt

G0JJY6 - G0JJY6_YERPE

Protein

Isocitrate dehydrogenase [NADP]

Gene

A1122_17675

Organism
Yersinia pestis A1122
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 19 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciYPES1035377:GLMV-3534-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    ORF Names:A1122_17675Imported
    OrganismiYersinia pestis A1122Imported
    Taxonomic identifieri1035377 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000002491: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliG0JJY6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    KOiK00031.
    OMAiCLRPIRY.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G0JJY6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MESKVVVPAE GKKITVDAQG KLVVPHNPII PFIEGDGIGV DVTPAMINVV    50
    DAAVKKAYNG ERKISWMEIY TGEKSTHVYG KDVWLPEETL DLIRDYRVAI 100
    KGPLTTPVGG GIRSLNVALR QQLDLYVCLR PVRYYEGTPS PVKHPELTNM 150
    VIFRENAEDI YAGIEWKAGS PEAEKVIKFL REEMGVKKIR FPEQCGIGVK 200
    PCSEEGTKRL VRAAIEYAIT NDRESVTLVH KGNIMKFTEG AFKDWGYQLA 250
    REEFGGELID GGPWVKIKNP NNGKEIIVKD VIADAFLQQI LLRPAEYDVI 300
    ACMNLNGDYI SDALAAQVGG IGIAPGANIG DDCALFEATH GTAPKYAGQD 350
    KVNPGSIILS AEMMLRHMGW FEAADLIIKG TEGAIQAKTV TYDFERLMEG 400
    AKLLKCSEFG DAIIKHM 417
    Length:417
    Mass (Da):45,868
    Last modified:October 19, 2011 - v1
    Checksum:iF908FB962F0F4932
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002956 Genomic DNA. Translation: AEL74152.1.
    RefSeqiYP_005523172.1. NC_017168.1.

    Genome annotation databases

    EnsemblBacteriaiAEL74152; AEL74152; A1122_17675.
    GeneIDi12112174.
    KEGGiypt:A1122_17675.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002956 Genomic DNA. Translation: AEL74152.1 .
    RefSeqi YP_005523172.1. NC_017168.1.

    3D structure databases

    ProteinModelPortali G0JJY6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEL74152 ; AEL74152 ; A1122_17675 .
    GeneIDi 12112174.
    KEGGi ypt:A1122_17675.

    Phylogenomic databases

    KOi K00031.
    OMAi CLRPIRY.

    Enzyme and pathway databases

    BioCyci YPES1035377:GLMV-3534-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Finished sequence of Yersinia pestis A1122."
      Doggett N., Munk A.C., Bruce D.C., Detter J.C., Johnson S.L., Han C.
      Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: A1122Imported.

    Entry informationi

    Entry nameiG0JJY6_YERPE
    AccessioniPrimary (citable) accession number: G0JJY6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3