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G0JJY6

- G0JJY6_YERPE

UniProt

G0JJY6 - G0JJY6_YERPE

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Protein
Isocitrate dehydrogenase [NADP]
Gene
A1122_17675
Organism
Yersinia pestis A1122
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  3. magnesium ion binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciYPES1035377:GLMV-3534-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
ORF Names:A1122_17675Imported
OrganismiYersinia pestis A1122Imported
Taxonomic identifieri1035377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000002491: Chromosome

Structurei

3D structure databases

ProteinModelPortaliG0JJY6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00031.
OMAiCLRPIRY.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0JJY6-1 [UniParc]FASTAAdd to Basket

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MESKVVVPAE GKKITVDAQG KLVVPHNPII PFIEGDGIGV DVTPAMINVV    50
DAAVKKAYNG ERKISWMEIY TGEKSTHVYG KDVWLPEETL DLIRDYRVAI 100
KGPLTTPVGG GIRSLNVALR QQLDLYVCLR PVRYYEGTPS PVKHPELTNM 150
VIFRENAEDI YAGIEWKAGS PEAEKVIKFL REEMGVKKIR FPEQCGIGVK 200
PCSEEGTKRL VRAAIEYAIT NDRESVTLVH KGNIMKFTEG AFKDWGYQLA 250
REEFGGELID GGPWVKIKNP NNGKEIIVKD VIADAFLQQI LLRPAEYDVI 300
ACMNLNGDYI SDALAAQVGG IGIAPGANIG DDCALFEATH GTAPKYAGQD 350
KVNPGSIILS AEMMLRHMGW FEAADLIIKG TEGAIQAKTV TYDFERLMEG 400
AKLLKCSEFG DAIIKHM 417
Length:417
Mass (Da):45,868
Last modified:October 19, 2011 - v1
Checksum:iF908FB962F0F4932
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002956 Genomic DNA. Translation: AEL74152.1.
RefSeqiYP_005523172.1. NC_017168.1.

Genome annotation databases

EnsemblBacteriaiAEL74152; AEL74152; A1122_17675.
GeneIDi12112174.
KEGGiypt:A1122_17675.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002956 Genomic DNA. Translation: AEL74152.1 .
RefSeqi YP_005523172.1. NC_017168.1.

3D structure databases

ProteinModelPortali G0JJY6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEL74152 ; AEL74152 ; A1122_17675 .
GeneIDi 12112174.
KEGGi ypt:A1122_17675.

Phylogenomic databases

KOi K00031.
OMAi CLRPIRY.

Enzyme and pathway databases

BioCyci YPES1035377:GLMV-3534-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Finished sequence of Yersinia pestis A1122."
    Doggett N., Munk A.C., Bruce D.C., Detter J.C., Johnson S.L., Han C.
    Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A1122Imported.

Entry informationi

Entry nameiG0JJY6_YERPE
AccessioniPrimary (citable) accession number: G0JJY6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: May 14, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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