ID   G0J490_CYCMS            Unreviewed;       385 AA.
AC   G0J490;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   OrderedLocusNames=Cycma_3805 {ECO:0000313|EMBL:AEL27516.1};
OS   Cyclobacterium marinum (strain ATCC 25205 / DSM 745 / LMG 13164 / NCIMB
OS   1802) (Flectobacillus marinus).
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC   Cyclobacterium.
OX   NCBI_TaxID=880070 {ECO:0000313|EMBL:AEL27516.1, ECO:0000313|Proteomes:UP000001635};
RN   [1] {ECO:0000313|Proteomes:UP000001635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25205 / DSM 745 / LMG 13164 / NCIMB 1802
RC   {ECO:0000313|Proteomes:UP000001635};
RA   Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Chertkov O.,
RA   Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA   Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B., Schuetze A.,
RA   Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Cyclobacterium marinum DSM 745.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002955; AEL27516.1; -; Genomic_DNA.
DR   RefSeq; WP_014021801.1; NC_015914.1.
DR   AlphaFoldDB; G0J490; -.
DR   STRING; 880070.Cycma_3805; -.
DR   KEGG; cmr:Cycma_3805; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_024620_1_0_10; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000001635; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AEL27516.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001635};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          55..359
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   385 AA;  42628 MW;  67E89E2401564C97 CRC64;
     MLNLLFYFIS LYLSTLLQIY VPERFNQIVE QDLFVAGEGG YHTYRIPSLL VTGNGTVLAF
     VEGRKSGQGD TGDIDLLMKK STDGGRTWSK QVVIWDDGES VCGNPNPVLD EVTGDIHLLL
     TWNRGDDHEG DIITKKSKDI RRVFVMKSSD NGDSWSAPVD ITKTTKNPLW GWYATGPGMG
     IQIKHGPNKG RLVIPANHSY DDPNGEVRGG PFEYGAHVIF SDDHGVTWEL GGSIRPKMNE
     SQLIEMADGK GTLLMNMRSY YGKNRRALSV SKDGGETWSD PVEATSLIEP VCQAAFIRYS
     WPDEKGKDLV LFSNPSSTKR ENMTIKLSKD SGKTWIASKV LNQGPSAYSA LAALPNGDIL
     CLYEKGEKNP YEKLVLSHLS LDNMQ
//