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Protein
Submitted name:

Alanine racemase

Gene

Cycma_1700

Organism
Cyclobacterium marinum (strain ATCC 25205 / DSM 745) (Flectobacillus marinus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei590 – 5901SubstrateUniRule annotation
Binding sitei767 – 7671Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCMAR880070:GHDK-1710-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Alanine racemaseImported
Gene namesi
Ordered Locus Names:Cycma_1700Imported
OrganismiCyclobacterium marinum (strain ATCC 25205 / DSM 745) (Flectobacillus marinus)Imported
Taxonomic identifieri880070 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCyclobacteriaceaeCyclobacterium
Proteomesi
  • UP000001635 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei493 – 4931N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi880070.Cycma_1700.

Structurei

3D structure databases

ProteinModelPortaliG0IUR2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini697 – 821125Ala_racemase_CInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105CJ4. Bacteria.
COG0770. LUCA.
COG0787. LUCA.
KOiK01775.
OMAiMVKAFAY.
OrthoDBiPOG091H022F.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.1190.10. 1 hit.
3.40.1390.10. 1 hit.
3.90.190.20. 1 hit.
HAMAPiMF_01201. Ala_racemase. 1 hit.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
SSF63418. SSF63418. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

G0IUR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQINFSQFA SNQSSLFIPG TPDESILFAV IDSRKIHSGK ETLFIALQGS
60 70 80 90 100
RHAGWEFATD AYAKGVRNFI LPKICPSSLL KKLANANILL SISPLKELQQ
110 120 130 140 150
LAQINREAFR GAVIGITGSN GKTIVKEWLA QVLSAQFNLW KSPKSYNSQI
160 170 180 190 200
GVALSALGIN PQHQLAILEA GISAPDEMKA LQEIIQPQLG IFTNIGSAHD
210 220 230 240 250
ENFKDTTSKI IEKCLLFKDV KFLVYNKDQE LVSNYLASSF DPSVRISWSD
260 270 280 290 300
KPGADYVLSV KPHRNGTKIY MMGKDLRTFT FYTSFRDKAS LENLRHVITA
310 320 330 340 350
ALSLGMEPLM IQQGLELLHA VDMRLTLKSG LNGCKLIDDS YNNDLAGLEL
360 370 380 390 400
ALEFMHQQVT TSGRKILILS EIQQDGDITA TFKKIAWLLG QYDIDLFIGV
410 420 430 440 450
GKGFEESKAL FPCESRCFED TDSLLKGMET LSLSNDLILI KGARVYKFER
460 470 480 490 500
IVQKLEALAH ETILEINLNA LRHNFMHYRQ KLKVGTKIMV MVKAFAYGGG
510 520 530 540 550
AAEIGNYLQE IGADYLSVAY TDEGIFLRNN GISLPIMVMN PGSFHLDLLQ
560 570 580 590 600
THALEPVVYN LQQLRTLSAS IDDYSGELPV HLEFDTGMRR LGMTEEDLDE
610 620 630 640 650
VIEILLHNKK IKVAGIFTHL AGADEAIHKD YTLSQLASFE IWSKKLMDNT
660 670 680 690 700
GCRPLRHCLN SAGIIRYPEY AHDMVRLGIG LYGIEVNKME QNKLEPAMVL
710 720 730 740 750
KTVVSQVKTL AKGATVGYGR VGKMKTEGEV ATLAIGYADG YDRRFSNGNA
760 770 780 790 800
KVLIKGKLVP ILGNVCMDMC MADVTGLNVC VGDEAILFGE QPSIIDLADK
810 820
IGTIPYELLT GIGPRVKRQY VLD
Length:823
Mass (Da):91,253
Last modified:October 19, 2011 - v1
Checksum:i85365B6FC40B9279
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002955 Genomic DNA. Translation: AEL25454.1.
RefSeqiWP_014019749.1. NC_015914.1.

Genome annotation databases

EnsemblBacteriaiAEL25454; AEL25454; Cycma_1700.
KEGGicmr:Cycma_1700.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002955 Genomic DNA. Translation: AEL25454.1.
RefSeqiWP_014019749.1. NC_015914.1.

3D structure databases

ProteinModelPortaliG0IUR2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi880070.Cycma_1700.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEL25454; AEL25454; Cycma_1700.
KEGGicmr:Cycma_1700.

Phylogenomic databases

eggNOGiENOG4105CJ4. Bacteria.
COG0770. LUCA.
COG0787. LUCA.
KOiK01775.
OMAiMVKAFAY.
OrthoDBiPOG091H022F.

Enzyme and pathway databases

BioCyciCMAR880070:GHDK-1710-MONOMER.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.1190.10. 1 hit.
3.40.1390.10. 1 hit.
3.90.190.20. 1 hit.
HAMAPiMF_01201. Ala_racemase. 1 hit.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
SSF63418. SSF63418. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiG0IUR2_CYCMS
AccessioniPrimary (citable) accession number: G0IUR2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: September 7, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.