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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus pseudopneumoniae (strain IS7493)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei561 – 5611UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSPSE1054460:GHLA-1025-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:SPPN_05165Imported
OrganismiStreptococcus pseudopneumoniae (strain IS7493)Imported
Taxonomic identifieri1054460 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001637 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi1054460.SPPN_05165.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0I954-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLQKLENYS NKSVVQEEVL ILTELLEDIT KNMLAPETFE KIMQLKELST
60 70 80 90 100
QEDYQGLNRL VTSLSNDEMV YISRYFSILP LLINISEDVD LAYEINHQNN
110 120 130 140 150
IDQDYLGKLS TTIKMVAEKE NAAEILEHLN VVPVLTAHPT QVQRKSMLDL
160 170 180 190 200
TNHIHSLLRK YRDVKLGLIN KEKWHNDLRR YIEIIMQTDM IREKKLKVTN
210 220 230 240 250
EITNAMEYYN SSFLKAVPHL TTEYKRLAQA HGLNLKQAKP ITMGMWIGGD
260 270 280 290 300
RDGNPFVTAE TLKQSALTQC EVIMNYYDEK IYQLYREFSL STSIVNVSKQ
310 320 330 340 350
VREMARQSKD NSIYREKELY RRALFDIQSK IQATKTYLIE DKEVGTRYET
360 370 380 390 400
ANDFYKDLIA IRDSLLENKG ESLISGDFVE LLQAVEIFGF YLASIDMRQD
410 420 430 440 450
SSVYEACVAE LLKSAGIHSR YSELSEEEKC DLLLKELEED PRILSATHAE
460 470 480 490 500
KSELLAKELA IFKTARVLKD KLGDDVIRQT IISHATSLSD MLELAILLKE
510 520 530 540 550
VGLVDTERAR VQIVPLFETI EDLDHSEETM RKYLSLSLAK KWIASRNNYQ
560 570 580 590 600
EIMLGYSDSN KDGGYLSSCW TLYKAQQQLT AIGDEFGVKV TFFHGRGGTV
610 620 630 640 650
GRGGGPTYEA ITSQPLKSIK DRIRLTEQGE VIGNKYGNKD AAYYNLEMLV
660 670 680 690 700
SAAINRMITQ KKSDTNTSNR YEAIMDQVVD RSYDIYRDLV FGNEHFYDYF
710 720 730 740 750
FESSPIKAIS SFNIGSRPAA RKTITEIGGL RAIPWVFSWS QSRVMFPGWY
760 770 780 790 800
GVGSSFKEFI DKNPENIAIL RDMYQNWPFF QSLLSNVDMV LSKSNMNIAF
810 820 830 840 850
EYAKLCEDEQ VKVIYETILN EWQVTKNVIL AIEGHDELLA DNPYLKASLD
860 870 880 890
YRMPYFNILN YIQLELIKRQ RRGELSSDQE RLIHITINGI ATGLRNSG
Length:898
Mass (Da):103,257
Last modified:October 19, 2011 - v1
Checksum:i71945010F5AE4330
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002925 Genomic DNA. Translation: AEL10469.1.
RefSeqiWP_000058211.1. NC_015875.1.

Genome annotation databases

EnsemblBacteriaiAEL10469; AEL10469; SPPN_05165.
KEGGistd:SPPN_05165.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002925 Genomic DNA. Translation: AEL10469.1.
RefSeqiWP_000058211.1. NC_015875.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1054460.SPPN_05165.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEL10469; AEL10469; SPPN_05165.
KEGGistd:SPPN_05165.

Phylogenomic databases

KOiK01595.
OMAiFTSNWEL.

Enzyme and pathway databases

BioCyciSPSE1054460:GHLA-1025-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Whole-genome sequence of Streptococcus pseudopneumoniae isolate IS7493."
    Shahinas D., Tamber G.S., Arya G., Wong A., Lau R., Jamieson F., Ma J.H., Alexander D.C., Low D.E., Pillai D.R.
    J. Bacteriol. 193:6102-6103(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IS7493Imported.

Entry informationi

Entry nameiG0I954_STRES
AccessioniPrimary (citable) accession number: G0I954
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: July 22, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.