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G0I6R8 (G0I6R8_STRES) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 10. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
EC=3.6.1.27 HAMAP-Rule MF_01006
Alternative name(s):
Bacitracin resistance protein HAMAP-Rule MF_01006
Undecaprenyl pyrophosphate phosphatase HAMAP-Rule MF_01006
Gene names
Name:uppP HAMAP-Rule MF_01006
Ordered Locus Names:SPPN_02820 EMBL AEL10004.1
OrganismStreptococcus pseudopneumoniae (strain IS7493) [Complete proteome] [HAMAP] EMBL AEL10004.1
Taxonomic identifier1054460 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus ›

Protein attributes

Sequence length281 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006 SAAS SAAS003824

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available By similarity. HAMAP-Rule MF_01006

Sequence similarities

Belongs to the UppP family. HAMAP-Rule MF_01006

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane4 – 2421Helical; By similarity HAMAP-Rule MF_01006
Transmembrane45 – 6521Helical; By similarity HAMAP-Rule MF_01006
Transmembrane89 – 10921Helical; By similarity HAMAP-Rule MF_01006
Transmembrane113 – 13321Helical; By similarity HAMAP-Rule MF_01006
Transmembrane152 – 17221Helical; By similarity HAMAP-Rule MF_01006
Transmembrane190 – 21021Helical; By similarity HAMAP-Rule MF_01006
Transmembrane225 – 24521Helical; By similarity HAMAP-Rule MF_01006
Transmembrane257 – 27721Helical; By similarity HAMAP-Rule MF_01006

Sequences

Sequence LengthMass (Da)Tools
G0I6R8 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: 75F6B5E1E22F4EF6

FASTA28131,833
        10         20         30         40         50         60 
MYLIEILKSI FFGIVEGITE WLPISSTGHL ILAEEFIQYQ NQNEAFISMF NVVIQLGAIL 

        70         80         90        100        110        120 
AVMVIYFNKL NPFKPTKDKQ EVRKTWRLWL KVLIATLPLL AVFKFDDWFD THFHNMVSVA 

       130        140        150        160        170        180 
LMLIIYGIAF IYLEKRNKAR AIEPSVTELD KLPYTTAFYI GLFQVLALLP GTSRSGATIV 

       190        200        210        220        230        240 
GGLLNGTSRS VVTEFTFYLG IPVMFGASAL KIFKFLKAGQ LLSFGQLFLL LVAMGVAFAV 

       250        260        270        280 
SMVAIRFLTS YVKKHDFTLF GKYRIVLGSV LLLYSFVRLF V

« Hide

References

[1]"Whole-Genome Sequence of Streptococcus pseudopneumoniae Isolate IS7493."
Shahinas D., Tamber G.S., Arya G., Wong A., Lau R., Jamieson F., Ma J.H., Alexander D.C., Low D.E., Pillai D.R.
J. Bacteriol. 193:6102-6103(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IS7493 EMBL AEL10004.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002925 Genomic DNA. Translation: AEL10004.1.
RefSeqYP_004767864.1. NC_015875.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEL10004; AEL10004; SPPN_02820.
GeneID11028073.
KEGGstd:SPPN_02820.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK06153.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. Bacitracin-R_BacA.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0I6R8_STRES
AccessionPrimary (citable) accession number: G0I6R8
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: April 3, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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